ZFIN ID: ZDB-PUB-070806-28
It takes guts to make a single lumen
Belting, H.G., and Affolter, M.
Date: 2007
Source: Nature cell biology   9(8): 880-881 (Journal)
Registered Authors: Affolter, Markus, Belting, Heinz-Georg Paul (Henry)
Keywords: none
MeSH Terms:
  • Animals
  • Biological Transport/physiology
  • Claudins
  • Hepatocyte Nuclear Factor 1-beta/genetics
  • Hepatocyte Nuclear Factor 1-beta/metabolism
  • Intestines*/anatomy & histology
  • Intestines*/embryology
  • Membrane Proteins/genetics
  • Membrane Proteins/metabolism
  • Morphogenesis*
  • Zebrafish*/anatomy & histology
  • Zebrafish*/embryology
  • Zebrafish Proteins/genetics
  • Zebrafish Proteins/metabolism
PubMed: 17671457 Full text @ Nat. Cell Biol.
ABSTRACT
A new study of the zebrafish intestine has uncovered a transcriptional hierarchy controlling lumen formation and proposes a model for how transcellular and paracellular transport synergize to ensure that only a single lumen is produced.
ADDITIONAL INFORMATION No data available