PUBLICATION
Neurogenesis in the fish retina
- Authors
- Stenkamp, D.L.
- ID
- ZDB-PUB-070424-8
- Date
- 2007
- Source
- International review of cytology 259(1): 173-224 (Review)
- Registered Authors
- Stenkamp, Deborah L.
- Keywords
- none
- MeSH Terms
-
- Animals
- Nerve Regeneration*
- Organogenesis
- Photoreceptor Cells, Vertebrate/physiology
- Retina/embryology
- Retina/injuries
- Retina/physiology*
- Signal Transduction
- Stem Cells/physiology
- Visual Pathways/embryology
- Visual Pathways/physiology*
- Zebrafish/embryology
- Zebrafish/physiology*
- PubMed
- 17425942 Full text @ Int. Rev. Cytol.
Citation
Stenkamp, D.L. (2007) Neurogenesis in the fish retina. International review of cytology. 259(1):173-224.
Abstract
The retinas of teleost fish have long been of interest to developmental neurobiologists for their persistent plasticity during growth, life history changes, and response to injury. Because the vertebrate retina is a highly conserved tissue, the study of persistent plasticity in teleosts has provided insights into mechanisms for postembryonic retinal neurogenesis in mammals. In addition, in the past 10 years there has been an explosion in the use of teleost fish-zebrafish (Danio rerio) in particular-to understand the mechanisms of embryonic retinal neurogenesis in a model vertebrate with genetic resources. This review summarizes the key features of teleost retinal neurogenesis that make it a productive and interesting experimental system, and focuses on the contributions to our knowledge of retinal neurogenesis that uniquely required or significantly benefited from the use of a fish model system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping