PUBLICATION

Signaling networks that regulate muscle development: lessons from zebrafish

Authors
Ochi, H., and Westerfield, M.
ID
ZDB-PUB-070210-7
Date
2007
Source
Development, growth & differentiation   49(1): 1-11 (Review)
Registered Authors
Ochi, Haruki, Westerfield, Monte
Keywords
none
MeSH Terms
  • Animals
  • Gastrula/cytology
  • Gastrula/physiology
  • Mesoderm/cytology
  • Mesoderm/physiology*
  • Muscle Development
  • Muscle, Skeletal/embryology*
  • Myogenic Regulatory Factors/genetics
  • Myogenic Regulatory Factors/metabolism*
  • Signal Transduction/physiology*
  • Stem Cells/cytology
  • Stem Cells/physiology*
  • Zebrafish/embryology*
  • Zebrafish/genetics
PubMed
17227340 Full text @ Dev. Growth Diff.
Abstract
Locomotion mediated by skeletal muscle provides a basis for the behavioral repertoire of most animals. Embryological and genetic studies of mouse, bird, fish and frog embryos are providing insights into the functions of the myogenic regulatory factors (MRFs) and the signaling molecules that regulate activity of MRFs. Nevertheless, our understanding of muscle development remains somewhat limited. Fundamental goals are to elucidate how mesodermal cells are induced during gastrulation to form muscle precursor cells and how muscle precursor cells acquire specific cell fates, such as slow and fast muscle cells. In this review, we focus on studies of zebrafish muscle development that have advanced our understanding of the molecular genetics of muscle cell induction and specification.
Genes / Markers
Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes