PUBLICATION
Gastrulation in zebrafish - all just about adhesion?
- Authors
- Solnica-Krezel, L.
- ID
- ZDB-PUB-060703-5
- Date
- 2006
- Source
- Current opinion in genetics & development 16(4): 433-441 (Review)
- Registered Authors
- Solnica-Krezel, Lilianna
- Keywords
- none
- MeSH Terms
-
- Animals
- Cadherins/physiology
- Cell Adhesion
- Cell Movement/genetics
- Cytoskeleton/physiology
- Gastrula/cytology*
- Gastrula/physiology*
- Gene Expression Regulation, Developmental
- Mesoderm/cytology
- Zebrafish/embryology*
- PubMed
- 16797963 Full text @ Curr. Opin. Genet. Dev.
Citation
Solnica-Krezel, L. (2006) Gastrulation in zebrafish - all just about adhesion?. Current opinion in genetics & development. 16(4):433-441.
Abstract
During vertebrate gastrulation, the evolutionarily conserved morphogenetic movements of epiboly, internalization, convergence and extension cooperate to generate germ layers and to sculpt the body plan. In zebrafish, these movements are driven by a variety of cell behaviors, including slow and fast directed migration, radial and mediolateral intercalation, and cell shape changes. Whereas some signaling pathways are required for a subset of these behaviors, other molecules, such as E-cadherin or Galpha12 and Galpha13 proteins, appear to have a widespread role in different gastrulation cell behaviors.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping