ZFIN ID: ZDB-PUB-050518-12
Linkage mapping of the [pro2]somatostatin-14 gene in zebrafish: evolutionary perspectives
Tostivint, H., Joly, L., Lihrmann, I., Conlon, J.M., Ekker, M., and Vaudry, H.
Date: 2005
Source: Annals of the New York Academy of Sciences   1040: 486-489 (Journal)
Registered Authors: Ekker, Marc, Joly, Lucille, Tostivint, Hervé
Keywords: somatostatin; cortistatin; zebrafish; radiation hybrid mapping; comparative genomics; evolution
MeSH Terms:
  • Animals
  • Chromosome Mapping/methods*
  • Evolution, Molecular*
  • Humans
  • Somatostatin/analogs & derivatives
  • Somatostatin/genetics*
  • Zebrafish/genetics*
  • Zebrafish Proteins/genetics*
PubMed: 15891097 Full text @ Ann N Y Acad Sci
Radiation hybrid mapping assigned the zebrafish [Pro(2)]somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.