PUBLICATION
Linkage mapping of the [pro2]somatostatin-14 gene in zebrafish: evolutionary perspectives
- Authors
- Tostivint, H., Joly, L., Lihrmann, I., Conlon, J.M., Ekker, M., and Vaudry, H.
- ID
- ZDB-PUB-050518-12
- Date
- 2005
- Source
- Annals of the New York Academy of Sciences 1040: 486-489 (Journal)
- Registered Authors
- Ekker, Marc, Joly, Lucille, Tostivint, Hervé
- Keywords
- somatostatin; cortistatin; zebrafish; radiation hybrid mapping; comparative genomics; evolution
- MeSH Terms
-
- Zebrafish Proteins/genetics*
- Zebrafish/genetics*
- Humans
- Somatostatin/analogs & derivatives
- Somatostatin/genetics*
- Chromosome Mapping/methods*
- Evolution, Molecular*
- Animals
- PubMed
- 15891097 Full text @ Ann N Y Acad Sci
Citation
Tostivint, H., Joly, L., Lihrmann, I., Conlon, J.M., Ekker, M., and Vaudry, H. (2005) Linkage mapping of the [pro2]somatostatin-14 gene in zebrafish: evolutionary perspectives. Annals of the New York Academy of Sciences. 1040:486-489.
Abstract
Radiation hybrid mapping assigned the zebrafish [Pro(2)]somatostatin-14 (also termed somatostatin 2; SS2) gene to linkage group 23 of the zebrafish genome, close to the marker nadl1.2. Comparative genomic analysis revealed conserved syntenies of the SS2 gene locus with part of the human 1p36 region, where the cortistatin gene is located. This observation strongly suggests that the SS2 gene in nonmammalian species and the cortistatin gene in mammals are orthologous.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping