PUBLICATION
Gastrulation dynamics: cells move into focus
- Authors
- Montero, J.A., and Heisenberg, C.P.
- ID
- ZDB-PUB-041104-4
- Date
- 2004
- Source
- Trends in cell biology 14(11): 620-627 (Review)
- Registered Authors
- Heisenberg, Carl-Philipp, Montero-Simon, Juan-Antonio
- Keywords
- none
- MeSH Terms
-
- Animals
- Cell Movement/physiology
- Gastrula/cytology*
- Signal Transduction
- Zebrafish/embryology*
- Zebrafish/genetics
- PubMed
- 15519851 Full text @ Trends Cell Biol.
Citation
Montero, J.A., and Heisenberg, C.P. (2004) Gastrulation dynamics: cells move into focus. Trends in cell biology. 14(11):620-627.
Abstract
During vertebrate gastrulation, a relatively limited number of blastodermal cells undergoes a stereotypical set of cellular movements that leads to formation of the three germ layers: ectoderm, mesoderm and endoderm. Gastrulation, therefore, provides a unique developmental system in which to study cell movements in vivo in a fairly simple cellular context. Recent advances have been made in elucidating the cellular and molecular mechanisms that underlie cell movements during zebrafish gastrulation. These findings can be compared with observations made in other model systems to identify potential general mechanisms of cell migration during development.
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