PUBLICATION

Spatial and temporal expression patterns of selenoprotein genes during embryogenesis in zebrafish

Authors
Thisse, C., Degrave, A., Kryukov, G.V., Gladyshev, V.N., Obrecht-Pflumio, S., Krol, A., Thisse, B., and Lescure, A.
ID
ZDB-PUB-030826-18
Date
2003
Source
Gene expression patterns : GEP   3(4): 525-532 (Journal)
Registered Authors
Degrave, Agnes, Gladyshev, Vadim, Krol, Alain, Kryukov, Gregory, Lescure, Alain, Obrecht-Pflumio, Sophie, Thisse, Bernard, Thisse, Christine
Keywords
none
MeSH Terms
  • Animals
  • Gene Expression Regulation, Developmental
  • In Situ Hybridization
  • Molecular Sequence Data
  • Proteins/genetics*
  • Proteins/metabolism
  • RNA Probes
  • RNA, Messenger/metabolism
  • Selenoproteins
  • Tissue Distribution
  • Zebrafish/embryology*
  • Zebrafish Proteins
PubMed
12915322 Full text @ Gene Expr. Patterns
Abstract
Selenium is important for embryogenesis in vertebrates but little is known about the expression patterns and biological functions of most selenoprotein genes. Taking advantage of the zebrafish model, systematic analysis of selenoprotein gene expression was performed by in situ hybridization on whole-mount embryos at different developmental stages. Twenty-one selenoprotein mRNAs were analyzed and all of them exhibited expression patterns restricted to specific tissues. Moreover, we demonstrated that highly similar selenoprotein paralogs were expressed within distinct territories. Therefore, tissue- and development-specific expression patterns provided new information for selenoproteins of unknown function.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes