PUBLICATION

Sequence and embryonic expression of collagen XVIII NC1 domain (endostatin) in the zebrafish

Authors
Haftek, Z., Morvan-Dubois, G., Thisse, B., Thisse, C., Garrone, R., and Le Guellec, D.
ID
ZDB-PUB-030716-15
Date
2003
Source
Gene expression patterns : GEP   3(3): 351-354 (Journal)
Registered Authors
Le Guellec, Dominique, Thisse, Bernard, Thisse, Christine
Keywords
none
MeSH Terms
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Endostatins/biosynthesis
  • Endostatins/genetics*
  • In Situ Hybridization
  • Molecular Sequence Data
  • Zebrafish/embryology*
  • Zebrafish/metabolism
PubMed
12799084 Full text @ Gene Expr. Patterns
Abstract
Endostatin, located in the NC1 domain of the collagen XVIII, is believed to inhibit the migration and proliferation of endothelial cells (Fed. Am. Soc. Exp. Biol. J. 15 (2001) 1044) and to play a role in axon guidance in Caenorhabditis elegans (J. Cell Biol. 152 (2001) 1219). Zebrafish is an attractive vertebrate model to determine the role of endostatin and the entire molecule of collagen XVIII during vertebrate development. Therefore, we have investigated the expression pattern of COL18A1 in zebrafish embryos from the segmentation to the hatching period stages.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes