PUBLICATION
The fates of zebrafish Hox gene duplicates
- Authors
- Jozefowicz, C., McClintock, J., and Prince, V.
- ID
- ZDB-PUB-030707-6
- Date
- 2003
- Source
- Journal of structural and functional genomics 3(1-4): 185-194 (Review)
- Registered Authors
- McClintock, James, Prince, Victoria E.
- Keywords
- none
- MeSH Terms
-
- Animals
- Chordata, Nonvertebrate/genetics
- Evolution, Molecular*
- Gene Duplication*
- Genes, Homeobox*
- Multigene Family
- Phylogeny
- Zebrafish/genetics*
- PubMed
- 12836697 Full text @ J. Struct. Funct. Genom.
Citation
Jozefowicz, C., McClintock, J., and Prince, V. (2003) The fates of zebrafish Hox gene duplicates. Journal of structural and functional genomics. 3(1-4):185-194.
Abstract
In his 1970 book, Susumu Ohno stressed the importance of gene duplication in the evolution of the vertebrate genome and body plan. He elaborated the idea that duplication events provide novel genetic material on which evolution may act. Data are accumulating to show that extensive duplication events, perhaps incorporating the duplication of entire genomes, occurred in the lineage leading to teleost fishes. These duplications may have been pivotal in the explosive radiation of this highly successful vertebrate group. Thus, the teleosts provide us with an ideal opportunity to investigate the fates and functions of duplicated genes. A convenient system for these studies is the zebrafish, Danio rerio, which has become a popular genetic and embryological model.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping