ZFIN ID: ZDB-PUB-030103-3
Cell-lineage specific expression in transgenic zebrafish
Lin, S.
Date: 2002
Source: U.S. Patent: (Medical College of Georgia Research Institute, Inc.) : (Other)
Registered Authors: Lin, Shuo
Keywords: Patents; Genetic engineering; transgenic fish; Danio rerio
MeSH Terms: none
PubMed: none
Disclosed are transgenic fish, and a method of making transgenic fish, which express transgenes in stable and predictable tissue- or developmentally-specific patterns. The transgenic fish contain transgene constructs with homologous expression sequences. Also disclosed are methods of using such transgenic fish. Such expression of transgenes allow the study of developmental processes, the relationship of cell lineages, the assessment of the effect of specific genes and compounds on the development or maintenance of specific tissues or cell lineages, and the maintenance of lines of fish bearing mutant genes.