PUBLICATION
Primordial germ cell development in zebrafish
- Authors
- Raz, E.
- ID
- ZDB-PUB-021210-1
- Date
- 2002
- Source
- Seminars in cell & developmental biology 13: 489-495 (Review)
- Registered Authors
- Raz, Erez
- Keywords
- primordial germ cells; PGC; cell migration; germ plasm; zebrafish
- MeSH Terms
-
- Animals
- Cell Movement
- Embryonic and Fetal Development
- Germ Cells/cytology
- Germ Cells/growth & development*
- Totipotent Stem Cells/cytology
- Totipotent Stem Cells/physiology
- Zebrafish/embryology*
- PubMed
- 12468252 Full text @ Sem. Cell Dev. Biol.
Citation
Raz, E. (2002) Primordial germ cell development in zebrafish. Seminars in cell & developmental biology. 13:489-495.
Abstract
In sexually reproducing organisms, primordial germ cells (PGCs) give rise to gametes that are responsible for the development of a new organism in the next generation. These cells follow a characteristic developmental path that is manifested in specialized regulation of basic cell functions and behavior making them an attractive system for studying cell fate specification, differentiation and migration. This review summarizes studies aimed at understanding the development of this cell population in zebrafish and compares these results with those obtained in other model organisms.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping