ZFIN ID: ZDB-PUB-020912-10
Platelet-derived growth factor A (pdgf-a) expression during zebrafish embryonic development
Liu, L., Korzh, V., Balasubramaniyan, N.V., Ekker, M., and Ge, R.
Date: 2002
Source: Development genes and evolution   212(6): 298-301 (Journal)
Registered Authors: Balasubramaniyan, Nataraja, Ekker, Marc, Korzh, Vladimir, Liu, Lihui
Keywords: none
MeSH Terms:
  • Amino Acid Sequence
  • Animals
  • Conserved Sequence
  • Gene Expression Regulation, Developmental*
  • Humans
  • Molecular Sequence Data
  • Phylogeny
  • Platelet-Derived Growth Factor/chemistry
  • Platelet-Derived Growth Factor/genetics*
  • RNA, Messenger/genetics
  • RNA, Messenger/metabolism
  • Sequence Homology, Amino Acid
  • Zebrafish/embryology*
  • Zebrafish/genetics*
PubMed: 12211169 Full text @ Dev. Genes Evol.
Zebrafish pdgf-a gene was cloned and its expression pattern studied during zebrafish embryogenesis. Zebrafish pdgf-a mRNA was present at high levels in fertilized eggs as well as in all embryonic cells up to the end of gastrulation. Spatially restricted expression started after the onset of segmentation and was mainly localized in the developing pharyngeal arches. Transient expression was also detected in Kupffer's vesicle, a teleost-specific structure, and in lateral trunk and tail regions surrounding the neural keel, as well as areas of the developing pronephros.