PUBLICATION
Wiring the zebrafish: axon guidance and synaptogenesis
- Authors
- Hutson, L.D. and Chien, C.-B.
- ID
- ZDB-PUB-020227-5
- Date
- 2002
- Source
- Current opinion in neurobiology 12(1): 87-92 (Journal)
- Registered Authors
- Chien, Chi-Bin, Hutson, Lara
- Keywords
- none
- MeSH Terms
-
- Animals
- Axons/physiology*
- Nervous System/cytology*
- Nervous System/embryology*
- Neural Pathways/physiology
- Synapses/physiology*
- Zebrafish/embryology*
- PubMed
- 11861169 Full text @ Curr. Opin. Neurobiol.
Citation
Hutson, L.D. and Chien, C.-B. (2002) Wiring the zebrafish: axon guidance and synaptogenesis. Current opinion in neurobiology. 12(1):87-92.
Abstract
Many zebrafish mutants have specific defects in axon guidance or synaptogenesis, particularly in the retinotectal and motor systems. Several mutants have now been characterized in detail and/or cloned. A combination of genetic studies, in vivo imaging and new techniques for misexpressing genes or blocking their function promises to reveal the molecules and principles that govern wiring of the vertebrate nervous system.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping