ZFIN ID: ZDB-PUB-020219-7
Expression of the anti-dorsalizing morphogenetic protein gene in the zebrafish embryo
Dickmeis, T., Rastegar, S., Aanstad, P., Clark, M., Fischer, N., Korzh, V., and Strähle, U.
Date: 2001
Source: Development genes and evolution   211(11): 568-572 (Journal)
Registered Authors: Aanstad, Pia, Clark, Matthew D., Dickmeis, Thomas, Fischer, Nadine, Korzh, Vladimir, Rastegar, Sepand, Strähle, Uwe
Keywords: gastrulation; organizer; embryonic shield; zebrafish; prechordal plate
MeSH Terms:
  • Amino Acid Sequence
  • Animals
  • Bone Morphogenetic Proteins/genetics*
  • Bone Morphogenetic Proteins/physiology
  • Cloning, Molecular
  • Gene Expression
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Homology, Amino Acid
  • Zebrafish/embryology
  • Zebrafish/genetics*
  • Zebrafish Proteins
PubMed: 11862464 Full text @ Dev. Genes Evol.
The BMP3 related anti-dorsalizing morphogenetic protein (ADMP) has been proposed to function in the organizer of chick and Xenopus embryos. We report here the cloning and expression pattern of a zebrafish admp gene. The gene is expressed in involuting cells of the embryonic shield, but not in the noninvoluting forerunner cells. During gastrulation, admp transcripts are detected in the posterior prechordal plate, in the notochord primordium and in cells of the dorsal blastoderm margin. Expression is also detectable in the neuroectoderm overlying the posterior prechordal plate. Expression persists in the tail bud until the end of somitogenesis while expression in other areas disappears during early somitogenesis stages.