PUBLICATION
Organogenesis--heart and blood formation from the zebrafish point of view
- Authors
- Thisse, C. and Zon, L.I.
- ID
- ZDB-PUB-020122-4
- Date
- 2002
- Source
- Science (New York, N.Y.) 295(5554): 457-462 (Review)
- Registered Authors
- Thisse, Christine, Zon, Leonard I.
- Keywords
- none
- MeSH Terms
-
- Heart/embryology*
- Heart/physiology
- Cell Differentiation/genetics
- Cell Lineage
- Body Patterning
- Mutation
- Humans
- Blood Vessels/embryology*
- Gene Expression Regulation, Developmental*
- Hematopoiesis*/genetics
- Stem Cells/physiology
- Zebrafish/embryology*
- Zebrafish/genetics*
- Zebrafish/metabolism
- Animals
- Morphogenesis/genetics
- PubMed
- 11799232 Full text @ Science
Citation
Thisse, C. and Zon, L.I. (2002) Organogenesis--heart and blood formation from the zebrafish point of view. Science (New York, N.Y.). 295(5554):457-462.
Abstract
Organs are specialized tissues used for enhanced physiology and environmental adaptation. The cells of the embryo are genetically programmed to establish organ form and function through conserved developmental modules. The zebrafish is a powerful model system that is poised to contribute to our basic understanding of vertebrate organogenesis. This review develops the theme of modules and illustrates how zebrafish have been particularly useful for understanding heart and blood formation.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping