PUBLICATION

Organogenesis--heart and blood formation from the zebrafish point of view

Authors
Thisse, C. and Zon, L.I.
ID
ZDB-PUB-020122-4
Date
2002
Source
Science (New York, N.Y.)   295(5554): 457-462 (Review)
Registered Authors
Thisse, Christine, Zon, Leonard I.
Keywords
none
MeSH Terms
  • Animals
  • Blood Vessels/embryology*
  • Body Patterning
  • Cell Differentiation/genetics
  • Cell Lineage
  • Gene Expression Regulation, Developmental*
  • Heart/embryology*
  • Heart/physiology
  • Hematopoiesis*/genetics
  • Humans
  • Morphogenesis/genetics
  • Mutation
  • Stem Cells/physiology
  • Zebrafish/embryology*
  • Zebrafish/genetics*
  • Zebrafish/metabolism
PubMed
11799232 Full text @ Science
Abstract
Organs are specialized tissues used for enhanced physiology and environmental adaptation. The cells of the embryo are genetically programmed to establish organ form and function through conserved developmental modules. The zebrafish is a powerful model system that is poised to contribute to our basic understanding of vertebrate organogenesis. This review develops the theme of modules and illustrates how zebrafish have been particularly useful for understanding heart and blood formation.
Genes / Markers
Figures
Show all Figures
Expression
Phenotype
Mutation and Transgenics
Human Disease / Model Data
Sequence Targeting Reagents
Fish
Antibodies
Orthology
Engineered Foreign Genes
Mapping
Errata and Notes