ZFIN ID: ZDB-PUB-011214-13
Sequence and expression pattern of ziro7, a novel, divergent zebrafish iroquois homeobox gene
Lecaudey, V., Thisse, C., Thisse, B., and Schneider-Maunoury, S.
Date: 2001
Source: Mechanisms of Development   109(2): 383-388 (Journal)
Registered Authors: Lecaudey, Virginie, Thisse, Bernard, Thisse, Christine
Keywords: Iroquois, homeobox, transcription factor, embryo, development, zebrafish, epiboly, gastrulation, neurulation, central nervous system, neural plate, hindbrain, midbrain, diencephalon, rhombomere, midbrain-hindbrain, Goosecoid expression, Xenopus homolog, Drosophila eye, neural plate, complex, identification, specification, neurogenesis, organization, boundaries boundary, mid-diencephalic boundary, pharyngeal arch
MeSH Terms:
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Embryo, Nonmammalian/metabolism
  • Homeodomain Proteins/biosynthesis*
  • Homeodomain Proteins/genetics*
  • In Situ Hybridization
  • Molecular Sequence Data
  • Neural Crest/embryology
  • Sequence Homology, Amino Acid
  • Time Factors
  • Tissue Distribution
  • Transcription Factors/biosynthesis*
  • Transcription Factors/genetics*
  • Zebrafish
  • Zebrafish Proteins*
PubMed: 11731254 Full text @ Mech. Dev.
We have isolated the zebrafish ziro7 gene, a novel, divergent member of the Iroquois family. ziro7 is expressed at early epiboly stages in the dorsal half of the zebrafish embryo, with a higher level in the dorso-lateral margin. From mid-gastrulation stages onward, ziro7 is expressed in a large transversal stripe in the future neural plate, which subsequently divides into thinner stripes located in the diencephalon, midbrain and hindbrain.