PUBLICATION
Morphogen gradients: nodal enters the stage
- Authors
- Kodjabachian, L.
- ID
- ZDB-PUB-010905-5
- Date
- 2001
- Source
- Current biology : CB 11(16): R655-R658 (Review)
- Registered Authors
- Kodjabachian, Laurent
- Keywords
- none
- MeSH Terms
-
- Animals
- Epidermal Growth Factor/metabolism
- Homeodomain Proteins/genetics
- Homeodomain Proteins/metabolism
- Mesoderm/chemistry
- Mesoderm/physiology*
- Morphogenesis/physiology*
- Nodal Signaling Ligands
- Signal Transduction/physiology*
- Transcription Factors/genetics
- Transcription Factors/metabolism
- Transforming Growth Factor beta/genetics
- Transforming Growth Factor beta/metabolism*
- Zebrafish/genetics
- Zebrafish/physiology
- Zebrafish Proteins*
- PubMed
- 11525759 Full text @ Curr. Biol.
Citation
Kodjabachian, L. (2001) Morphogen gradients: nodal enters the stage. Current biology : CB. 11(16):R655-R658.
Abstract
Morphogen gradients are proposed to organise cell fates during development via the long-range activity of secreted molecules. Their existence in vertebrates, however, has been debated. A recent study has identified the Nodal-related protein Squint as a bona fide morphogen in vertebrate mesoderm.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping