PUBLICATION
Studying vascular development in the zebrafish
- Authors
- Vogel, A.M. and Weinstein, B.M.
- ID
- ZDB-PUB-010601-10
- Date
- 2000
- Source
- Trends in cardiovascular medicine 10(8): 352-360 (Review)
- Registered Authors
- Vogel, Andreas M., Weinstein, Brant M.
- Keywords
- none
- MeSH Terms
-
- Animals
- Arteries/anatomy & histology
- Arteries/embryology
- Arteries/growth & development
- Blood Vessels/anatomy & histology
- Blood Vessels/embryology*
- Blood Vessels/growth & development
- Body Patterning/physiology*
- Embryonic Development
- Endothelial Growth Factors/physiology
- Models, Animal*
- Morphogenesis
- Neovascularization, Physiologic*
- Signal Transduction
- Zebrafish/embryology*
- Zebrafish/genetics
- PubMed
- 11369262 Full text @ Trends Cardiovasc. Med.
Citation
Vogel, A.M. and Weinstein, B.M. (2000) Studying vascular development in the zebrafish. Trends in cardiovascular medicine. 10(8):352-360.
Abstract
The zebrafish, a genetically accessible vertebrate with an externally developing, optically clear embryo, is ideally suited for in vivo functional dissection of the embryonic development of the circulatory system. Here, we review the advantages of the zebrafish as a model system for studying vascular development, and describe genetic and experimental tools, methods and resources that have been developed to exploit these advantages. We also discuss briefly how some of these tools and methods can be brought to bear on problems of relevance to human health.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping