PUBLICATION
Neural induction
- Authors
- Harland, R.
- ID
- ZDB-PUB-000825-3
- Date
- 2000
- Source
- Current opinion in genetics & development 10(4): 357-362 (Review)
- Registered Authors
- Harland, Richard
- Keywords
- none
- MeSH Terms
-
- Animals
- Bone Morphogenetic Proteins/antagonists & inhibitors
- Cytoskeletal Proteins/metabolism
- Ectoderm/physiology
- Embryonic Induction/physiology*
- Mesoderm/physiology
- Mice
- Organizers, Embryonic/physiology
- Proto-Oncogene Proteins/metabolism
- Signal Transduction/physiology*
- Trans-Activators*
- Wnt Proteins
- Zebrafish Proteins*
- beta Catenin
- PubMed
- 10889069 Full text @ Curr. Opin. Genet. Dev.
Citation
Harland, R. (2000) Neural induction. Current opinion in genetics & development. 10(4):357-362.
Abstract
Development of neural fates from ectoderm is accompanied by the blockage of BMP signals at both protein and mRNA levels. Recent work has employed zebrafish, chick and mouse in addition to amphibians as models. Genetics has supplemented experimental embryology in enriching the understanding of the mechanism of neural induction and in posing new questions.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping