ZFIN ID: ZDB-PERS-991129-2
Chen, Mark Hung-Chih
Email: zohcchen@gate.sinica.edu.tw
Affiliation: Jen-Leih Wu Lab
Address: Laboratory of Marine Molecular Biology and Biotechnology Institute of Zoology Academia Sinica Nankang Taipei, 11529 Taiwan
Country: Taiwan
Phone: 886-2-2789-9534
Fax: 886-2-2785-8059


Laboratory of Marine Molecular Biology and Biotechnology
Institute of Zoology
Academia Sinica
Taipei 11529
Taiwan ROC


B.Sc., 1991, Biology, Fu-Jen Catholic University, Taipei, Taiwan.

M.Sc., 1994, Marine Biology, National Taiwan Ocean University, Taipei, Taiwan.

Ph.D. Candidate, Graduate Institute of Life Science, National Defense Medical Center, Taipei, Taiwan.


The role of Insulin-like growth factor (IGF) in zebrafish.

Chen, M.H., Hsu, L.C., Wu, J.L., Yeh, C.W., Tsai, J.N., Hseu, Y.C., and Hsu, L.S. (2014) Exposure to benzidine caused apoptosis and malformation of telencephalon region in zebrafish. Environmental toxicology. 29(12):1428-36
Li, Y.H., Chen, M.H., Gong, H.Y., Hu, S.Y., Li, Y.W., Lin, G.H., Lin, C.C., Liu, W., and Wu, J.L. (2010) Progranulin A-mediated MET signaling is essential for liver morphogenesis in zebrafish. The Journal of biological chemistry. 285(52):41001-41009
Hu, S.Y., Chen, M.H., Lin, Y.C., Lin, G.H., Gong, H.Y., and Wu, J.L. (2008) Cloning and functional analysis of the proximal promoter region of the three GnRH genes from the silver sea bream (Sparus sarba). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 151(4):373-380
Hu, M.C., Gong, H.Y., Lin, G.H., Hu, S.Y., Chen, M.H., Huang, S.J., Liao, C.F., and Wu, J.L. (2007) XBP-1, a key regulator of unfolded protein response, activates transcription of IGF1 and Akt phosphorylation in zebrafish embryonic cell line. Biochemical and Biophysical Research Communications. 359(3):778-783
Gong, H.Y., Lin, C.J., Chen, M.H., Hu, M.C., Lin, G.H., Zhou, Y., Zon, L.I., and Wu, J.L. (2004) Two distinct teleost hepatocyte nuclear factor 1 genes, hnf1alpha/tcf1 and hnf1beta/tcf2, abundantly expressed in liver, pancreas, gut and kidney of zebrafish. Gene. 338(1):35-46
Huang, W.T., Gong, H.Y., Lin, C.J., Weng, C.F., Chen, M.H., and Wu, J.L. (2001) Hepatocyte nuclear factors-1alpha, -1beta, and -3beta expressed in the gonad of tilapia (Oreochromis mossambicus). Biochemical and Biophysical Research Communications. 288(4):833-840
Chen, M.H., Lin, G., Gong, H., Weng, C., Chang, C., and Wu, J. (2001) The characterization of prepro-Insulin-like growth factor-1 Ea-2 expression and Insulin-like growth factor-1 genes (devoid 81 bp) in the zebrafish (Danio rerio). Gene. 268(1-2):67-75

1. Mark Hung-Chih Chen (1994) Cloning and Characterization of Insulin-like Growth Factor I cDNA from Black Seabream (Acanthopagrus schlegeli) M.S. Thesis. National Taiwan Ocean University, Taipei, Taiwan.
2. Chen MHC, Lin GH, Gong HY, Lee CY, Chang CY, Chen TT, Wu JL (1998) Cloning and characterization of insulin-like growth factor I cDNA from black seabream (Acathopagrus schlegeli). Zool Stud 37:213-221