ZFIN ID: ZDB-PERS-971016-18
Liao, Eric
Email: liaoce@chop.edu
URL: https://www.chopcranio.org/overview
Affiliation: Eric Liao Lab
Address: Colket Translational Research Center 11th floor. 3501 Civic Center Blvd. Philadelphia, PA. 19104
Country: United States
Phone: 215-590-3096


Murali, H., Wang, P., Liao, E.C., Wang, K. (2024) Genetic variant classification by predicted protein structure: A case study on IRF6. Computational and structural biotechnology journal. 23:892904892-904
Yoon, B., Yeung, P., Santistevan, N., Bluhm, L., Kawasaki, K., Kueper, J., Dubielzig, R., Vanoudenhove, J., Cotney, J., Liao, E.C., Grinblat, Y. (2022) Zebrafish models of Alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye. Biology Open. 11(5):
Alhazmi, N., Carroll, S.H., Kawasaki, K., Woronowicz, K.C., Hallett, S.A., Macias Trevino, C., Li, E.B., Baron, R., Gori, F., Yelick, P.C., Harris, M.P., Liao, E.C. (2021) Synergistic roles of Wnt modulators R-spondin2 and R-spondin3 in craniofacial morphogenesis and dental development. Scientific Reports. 11:5871
Carroll, S.H., Macias Trevino, C., Li, E.B., Kawasaki, K., Myers, N., Hallett, S.A., Alhazmi, N., Cotney, J., Carstens, R.P., Liao, E.C. (2020) An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates. Development (Cambridge, England). 147(24):
Pini, J., Kueper, J., Hu, Y.D., Kawasaki, K., Yeung, P., Tsimbal, C., Yoon, B., Carmichael, N., Maas, R.L., Cotney, J., Grinblat, Y., Liao, E.C. (2020) ALX1-related frontonasal dysplasia results from defective neural crest cell development and migration. EMBO Molecular Medicine. 12(10):e12013
Yang, X., Jounaidi, Y., Mukherjee, K., Fantasia, R.J., Liao, E.C., Yu, B., Forman, S.A. (2019) Drug-selective Anesthetic Insensitivity of Zebrafish Lacking γ-Aminobutyric Acid Type A Receptor β3 Subunits. Anesthesiology. 131(6):1276-1291
Mukherjee, K., Liao, E.C. (2018) Generation and characterization of a zebrafish muscle specific inducible Cre line. Transgenic Research. 27(6):559-569
Ishii, K., Mukherjee, K., Okada, T., Liao, E.C. (2018) Genetic Requirement of talin1 for Proliferation of Cranial Neural Crest Cells during Palate Development.. Plastic and reconstructive surgery. Global open. 6:e1633
Duncan, K., Mukherjee, K., Cornell, R.A., Liao, E.C. (2017) Zebrafish models of orofacial clefts. Developmental Dynamics : an official publication of the American Association of Anatomists. 246(11):897-914
Li, E.B., Truong, D., Hallett, S.A., Mukherjee, K., Schutte, B.C., Liao, E.C. (2017) Rapid functional analysis of computationally complex rare human IRF6 gene variants using a novel zebrafish model. PLoS Genetics. 13:e1007009
Ciarlo, C., Kaufman, C.K., Kinikoglu, B., Michael, J., Yang, S., D Amato, C., Blokzijl-Franke, S., den Hertog, J., Schlaeger, T.M., Zhou, Y., Liao, E., Zon, L.I. (2017) A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development. eLIFE. 6
Shaw, N.D., Brand, H., Kupchinsky, Z.A., Bengani, H., Plummer, L., Jones, T.I., Erdin, S., Williamson, K.A., Rainger, J., Stortchevoi, A., Samocha, K., Currall, B.B., Dunican, D.S., Collins, R.L., Willer, J.R., Lek, A., Lek, M., Nassan, M., Pereira, S., Kammin, T., Lucente, D., Silva, A., Seabra, C.M., Chiang, C., An, Y., Ansari, M., Rainger, J.K., Joss, S., Smith, J.C., Lippincott, M.F., Singh, S.S., Patel, N., Jing, J.W., Law, J.R., Ferraro, N., Verloes, A., Rauch, A., Steindl, K., Zweier, M., Scheer, I., Sato, D., Okamoto, N., Jacobsen, C., Tryggestad, J., Chernausek, S., Schimmenti, L.A., Brasseur, B., Cesaretti, C., García-Ortiz, J.E., Buitrago, T.P., Silva, O.P., Hoffman, J.D., Mühlbauer, W., Ruprecht, K.W., Loeys, B.L., Shino, M., Kaindl, A.M., Cho, C.H., Morton, C.C., Meehan, R.R., van Heyningen, V., Liao, E.C., Balasubramanian, R., Hall, J.E., Seminara, S.B., Macarthur, D., Moore, S.A., Yoshiura, K.I., Gusella, J.F., Marsh, J.A., Graham, J.M., Lin, A.E., Katsanis, N., Jones, P.L., Crowley, W.F., Davis, E.E., FitzPatrick, D.R., Talkowski, M.E. (2017) SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nature Genetics. 49(2):238-248
Ling, I.T., Rochard, L., Liao, E.C. (2017) Distinct requirements of wls, wnt9a, wnt5b and gpc4 in regulating chondrocyte maturation and timing of endochondral ossification. Developmental Biology. 421(2):219-232
Rochard, L., Monica, S.D., Ling, I.T., Kong, Y., Roberson, S., Harland, R., Halpern, M., Liao, E.C. (2016) Roles of Wnt pathway genes wls, wnt9a, wnt5b, frzb and gpc4 in regulating convergent-extension during zebrafish palate morphogenesis. Development (Cambridge, England). 143:2541-7
Mukherjee, K., Ishii, K., Pillalamarri, V., Kammin, T., Atkin, J.F., Hickey, S.E., Xi, Q.J., Gusella, J.F., Talkowski, M.E., Morton, C.C., Maas, R.L., Liao, E.C. (2016) Actin capping protein CAPZB regulates cell morphology, differentiation, and neural crest migration in craniofacial morphogenesis. Human molecular genetics. 25(7):1255-70
Kaufman, C.K., Mosimann, C., Fan, Z.P., Yang, S., Thomas, A.J., Ablain, J., Tan, J.L., Fogley, R.D., van Rooijen, E., Hagedorn, E.J., Ciarlo, C., White, R.M., Matos, D.A , Puller, A.C., Santoriello, C., Liao, E.C., Young, R.A., and Zon, L.I. (2016) A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation. Science (New York, N.Y.). 351(6272):aad2197
Rochard, L.J., Ling, I.T., Kong, Y., Liao, E.C. (2015) Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel's Cartilage. Journal of visualized experiments : JoVE. (105):e52935
Gfrerer, L., Shubinets, V., Hoyos, T., Kong, Y., Nguyen, C., Pietschmann, P., Morton, C.C., Maas, R.L., Liao, E.C. (2014) Functional Analysis of SPECC1L in Craniofacial Development and Oblique Facial Cleft Pathogenesis. Plastic and reconstructive surgery. 134:748-759
Kinikoglu, B., Kong, Y., and Liao, E.C. (2014) Characterization of cultured multipotent zebrafish neural crest cells. Experimental Biology and Medicine. 239(2):159-68
Gfrerer, L., Dougherty, M., and Liao, E.C. (2013) Visualization of Craniofacial Development in the sox10: kaede Transgenic Zebrafish Line Using Time-lapse Confocal Microscopy. Journal of visualized experiments : JoVE. (79):e50525
Kamel, G., Hoyos, T., Rochard, L., Dougherty, M., Tse, W., Shubinets, V., Grimaldi, M., and Liao, E.C. (2013) Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis. Developmental Biology. 381(2):423-33
Lindgren, A.M., Hoyos, T., Talkowski, M.E., Hanscom, C., Blumenthal, I., Chiang, C., Ernst, C., Pereira, S., Ordulu, Z., Clericuzio, C., Drautz, J.M., Rosenfeld, J.A., Shaffer, L.G., Velsher, L., Pynn, T., Vermeesch, J., Harris, D.J., Gusella, J.F., Liao, E.C., and Morton, C.C. (2013) Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate. Human genetics. 132(5):537-552
Dougherty, M., Kamel, G., Grimaldi, M., Gfrerer, L., Shubinets, V., Ethier, R., Hickey, G., Cornell, R.A., and Liao, E.C. (2013) Distinct requirements for wnt9a and irf6 in extension and integration mechanisms during zebrafish palate morphogenesis. Development (Cambridge, England). 140(1):76-81
Dougherty, M., Kamel, G., Shubinets, V., Hickey, G., Grimaldi, M., and Liao, E.C. (2012) Embryonic Fate Map of First Pharyngeal Arch Structures in the sox10: kaede Zebrafish Transgenic Model. The Journal of craniofacial surgery. 23(5):1333-1337
Curtin, E., Hickey, G., Kamel, G., Davidson, A.J., and Liao, E.C. (2011) Zebrafish wnt9a is expressed in pharyngeal ectoderm and is required for palate and lower jaw development. Mechanisms of Development. 128(1-2):104-115
Paw, B.H., Davidson, A.J., Zhou, Y., Li, R., Pratt, S.J., Lee, C., Trede, N.S., Brownlie, A., Donovan, A., Liao, E.C., Ziai, J.M., Drejer, A.H., Guo, W., Kim, C.H., Gwynn, B., Peters, L.L., Chernova, M.N., Alper, S.L., Zapata, A., Wickramasinghe, S.N., Lee, M.J., Lux, S.E., Fritz, A., Postlethwait, J.H., and Zon, L.I. (2003) Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency. Nature Genetics. 34(1):59-64
Shafizadeh, E., Paw, B.H., Foott, H., Liao, E.C., Barut, B.A., Cope, J.J., Zon, L.I., and Lin, S. (2002) Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency. Development (Cambridge, England). 129(18):4359-4370
Liao, E.C., Trede, N.S., Ransom, D., Zapata, A., Kieran, M., and Zon, L.I. (2002) Non-cell autonomous requirement for the bloodless gene in primitive hematopoiesis of zebrafish. Development (Cambridge, England). 129(3):649-659
Liao, E.C., Paw, B.H., Peters, L.L., Zapata, A., Pratt, S.J., Do, C.P., Lieschke, G., and Zon, L.I. (2000) Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid ß-spectrin structure, and function in red cell morphogenesis and membrane stability. Development (Cambridge, England). 127(23):5123-5132
Liao, E. (2000) Direct Submission of Mapping Data (Eric Liao). Direct Submission of Mapping Data.
Oates, A.C., Brownlie, A., Pratt, S.J., Irvine, D.V., Liao, E.C., Paw, B.H., Dorian, K.J., Johnson, S.L., Postlethwait, J.H., Zon, L.I., and Wilks, A.F. (1999) Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expresssion patterns: only jak2a is expressed during erythropoiesis. Blood. 94(8):2622-2636
Porcher, C., Liao, E.C., Fujiwara, Y., Zon, L.I., and Orkin, S.H. (1999) Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. Development (Cambridge, England). 126(20):4603-4615
Liao, E.C. and Zon, L.I. (1999) Simple sequence-length polymorphism analysis. In The Zebrafish: Genetics and Genomics, H.W. Detrich, III, M. Westerfield, and L.I. Zon, eds., San Diego, CA: Academic Press, Methods Cell Biol.. 60:181-183
Postlethwait, J.H, Yan, Y.-L., Gates, M.A., Horne, S., Amores, A., Brownlie, A., Donovan, A., Egan, E.S., Force, A., Gong, Z., Goutel, C., Fritz, A., Kelsh, R., Knapik, E., Liao, E., Paw, B., Ransom, D., Singer, A., Thomson, M., Abduljabbar, T.S., Yelick, P., Beier, D., Joly, J.-S., Larhammar, D., Rosa, F., Westerfield, M., Zon, L.I., Johnson, S.L., and Talbot, W.S. (1998) Vertebrate genome evolution and the zebrafish gene map. Nature Genetics. 18:345-349
Liao, E.C., Paw, B.H., Oates, A.C., Pratt, S.J., Postlethwait, J.H., and Zon, L.I. (1998) SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes & Development. 12:621-626