ZFIN ID: ZDB-PERS-970908-9
Lane, Mary Ellen
Email: Mary.E.Lane@uth.tmc.edu
Address: Assistant Dean of Admission The University of Texas Graduate School of Biomedical Sciences @Houston 6767 Bertner, BSRB 3.8467 Houston, TX 77030 USA
Phone: 713-500-9860
Fax: 713-500-9877

My research interests include the specification of axial pattern in the developing central nervous system. I am using a combination of genetics molecular biology and experimental embryology to dissect the earliest events involved in induction and patterning of the CNS, with a particular focus on posterior neuroectoderm.

Dalle Nogare, D.E., Pauerstein, P.T., and Lane, M.E. (2009) G2 acquisition by transcription-independent mechanism at the zebrafish midblastula transition. Developmental Biology. 326(1):131-142
Swindell, E.C., Zilinski, C.A., Hashimoto, R., Shah, R., Lane, M.E., and Jamrich, M. (2008) Regulation and function of foxe3 during early zebrafish development. Genesis (New York, N.Y. : 2000). 46(3):177-183
Nogare, D.E., Arguello, A., Sazer, S., and Lane, M.E. (2007) Zebrafish cdc25a is expressed during early development and limiting for post-blastoderm cell cycle progression. Developmental dynamics : an official publication of the American Association of Anatomists. 236(12):3427-3435
McCollum, C.W., Amin, S.R., Pauerstein, P., and Lane, M.E. (2007) A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3. Developmental Biology. 309(2):373-385
Zilinski, C.A., Shah, R., Lane, M.E., and Jamrich, M. (2005) Modulation of zebrafish pitx3 expression in the primordia of the pituitary, lens, olfactory epithelium and cranial ganglia by hedgehog and nodal signaling. Genesis (New York, N.Y. : 2000). 41(1):33-40
Lane, M.E., Runko, A.P., Roy, N.M., and Sagerström, C.G. (2002) Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4. Mechanisms of Development. (Suppl.) 119:S185-S189
Sagerström, C.G., Kao, B.A., Lane, M.E., and Sive, H. (2001) Isolation and characterization of posteriorly restricted genes in the zebrafish gastrula. Developmental dynamics : an official publication of the American Association of Anatomists. 220(4):402-408
Grinblat, Y., Lane, M.E., Sagerström, C., and Sive, H. (1999) Analysis of zebrafish development using explant culture assays. In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.. 59:127-156

Original Reports

Lane, M.E., and Kalderon, D. 1993. Genetic investigation of cAMP-dependent protein kinase function in Drosophila development. Genes and Dev. 7, 1229-1243.

Lane, M.E., and Kalderon, D. 1994. RNA localization along the anteroposterior axis of the Drosophila oocyte requires PKA-mediated signal transduction to direct normal microtubule organization. Genes and Dev. 8, 2986-2995.

Lane, M.E., and Kalderon, D. 1995. Localization and function of protein kinase A during Drosophila oogenesis. Mech. of Dev. 49, 191-200.

Li, W., Ohlmeyer, J.T., Lane, M.E., and Kalderon, D. 1995. Function of protein kinase A in hedgehog signal transduction and Drosophila imiginal disc development. Cell 80, 553-562.

Lane, M.E., Sauer, K., Wallace, K., Jan, Y.N., Lehner, C.F., and Vaessin, H. 1996. DACAPO, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development. Cell 87, 1225-1235.

Thomas, B.J., Zavitz, K.H., Dong, X., Lane, M.E., Weigmann, K., Finley, R.L. Jr., Brent, R., Lehner, C.F. and Zipursky, S.L. 1997. roughex down-regulates G2 cyclins in G1. Genes and Dev. 11, 1289-1298.


Lehner, C.F., and Lane, M.E. Cell cycle regulators in Drosophila: Downstream and part of developmental decisions. J. Cell Sci. 110, 523-528.