ZFIN Person: Carl, Matthias

ZFIN ID: ZDB-PERS-970512-20

ZFIN ID: ZDB-PERS-970512-20

Carl, Matthias

Email:	matthias.carl@unitn.it
URL:	https://mcarl255.wixsite.com/mysite
Affiliation:	Matthias Carl Lab
Address:	Laboratory of Translational Neurogenetics University degli Studi di Trento Via Sommarive 9 38123 Trento-Povo https://www.cibio.unitn.it/744/laboratory-of-translational-neurogenetics
Country:
Phone:	39-0461-283931
Fax:	39-0461-283937
ORCID ID:	0000-0002-9936-5813

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Agostini, C., Bühler, A., Antico Calderone, A., Aadepu, N., Herder, C., Loosli, F., Carl, M. (2022) Conserved and diverged asymmetric gene expression in the brain of teleosts. Frontiers in cell and developmental biology. 10:1005776

Bühler, A., Carl, M. (2021) Zebrafish Tools for Deciphering Habenular Network-Linked Mental Disorders. Biomolecules. 11(2):

Albadri, S., Armant, O., Aljand-Geschwill, T., Del Bene, F., Carl, M., Strähle, U., Poggi, L. (2020) Expression of a Barhl1a reporter in subsets of retinal ganglion cells and commissural neurons of the developing zebrafish brain. Scientific Reports. 10:8814

Guglielmi, L., Bühler, A., Moro, E., Argenton, F., Poggi, L., Carl, M. (2020) Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry. Development (Cambridge, England). 147(6):

Imle, R., Wang, B.T., Stützenberger, N., Birkenhagen, J., Tandon, A., Carl, M., Himmelreich, N., Thiel, C., Gröne, H.J., Poschet, G., Völkers, M., Gülow, K., Schröder, A., Carillo, S., Mittermayr, S., Bones, J., Kamiński, M.M., Kölker, S., Sauer, S.W. (2019) ADP-dependent glucokinase regulates energy metabolism via ER-localized glucose sensing. Scientific Reports. 9:14248

Breuer, M., Guglielmi, L., Zielonka, M., Hemberger, V., Kölker, S., Okun, J.G., Hoffmann, G.F., Carl, M., Sauer, S.W., Opladen, T. (2019) QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis. PLoS One. 14:e0215162

Zielonka, M., Probst, J., Carl, M., Hoffmann, G.F., Kölker, S., Okun, J.G. (2019) Bioenergetic dysfunction in a zebrafish model of acute hyperammonemic decompensation. Experimental neurology. 314:91-99

Poggi, L., Casarosa, S., Carl, M. (2018) An Eye on the Wnt Inhibitory Factor Wif1. Frontiers in cell and developmental biology. 6:167

Roussigné, M., Wei, L., Tsingos, E., Kuchling, F., Alkobtawi, M., Tsalavouta, M., Wittbrodt, J., Carl, M., Blader, P., Wilson, S.W. (2018) Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells. Proceedings of the National Academy of Sciences of the United States of America. 115(42):E9812-E9821

Zielonka, M., Breuer, M., Okun, J.G., Carl, M., Hoffmann, G.F., Kölker, S. (2018) Pharmacologic rescue of hyperammonemia-induced toxicity in zebrafish by inhibition of ornithine aminotransferase. PLoS One. 13:e0203707

Dimitrov, B., Himmelreich, N., Hipgrave Ederveen, AL., Lüchtenborg, C., Okun, J.G., Breuer, M., Hutter, A.M., Carl, M., Guglielmi, L., Hellwig, A., Thiemann, K.C., Jost, M., Peters, V., Staufner, C., Hoffmann, G.F., Hackenberg, A., Paramasivam, N., Wiemann, S., Eils, R., Schlesner, M., Strahl, S., Brügger, B., Wuhrer, M., Christoph Korenke, G., and Thiel, C. (2018) Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolism as additional symptoms in a new patient with ATP6AP1-CDG. Molecular genetics and metabolism. 123(3):364-374

Choi, J.H., Jeong, Y.M., Kim, S., Lee, B., Ariyasiri, K., Kim, H.T., Jung, S.H., Hwang, K.S., Choi, T.I., Park, C.O., Huh, W.K., Carl, M., Rosenfeld, J.A., Raskin, S., Ma, A., Gecz, J., Kim, H.G., Kim, J.S., Shin, H.C., Park, D.S., Gerlai, R., Jamieson, B.B., Kim, J.S., Iremonger, K.J., Lee, S.H., Shin, H.S., Kim, C.H. (2018) Targeted knockout of a chemokine-like gene increases anxiety and fear responses. Proceedings of the National Academy of Sciences of the United States of America. 115(5):E1041-E1050

Beretta, C.A., Dross, N., Guglielmi, L., Bankhead, P., Soulika, M., Gutierrez-Triana, J.A., Paolini, A., Poggi, L., Falk, J., Ryu, S., Kapsimali, M., Engel, U., Carl, M. (2017) Early Commissural Diencephalic Neurons Control Habenular Axon Extension and Targeting. Current biology : CB. 27(2):270–278

Cepero Malo, M., Duchemin, A.L., Guglielmi, L., Patzel, E., Sel, S., Auffarth, G.U., Carl, M., Poggi, L. (2017) The Zebrafish Anillin-eGFP Reporter Marks Late Dividing Retinal Precursors and Stem Cells Entering Neuronal Lineages. PLoS One. 12:e0170356

Kopajtich, R., Murayama, K., Janecke, A.R., Haack, T.B., Breuer, M., Knisely, A.S., Harting, I., Ohashi, T., Okazaki, Y., Watanabe, D., Tokuzawa, Y., Kotzaeridou, U., Kölker, S., Sauer, S., Carl, M., Straub, S., Entenmann, A., Gizewski, E., Feichtinger, R.G., Mayr, J.A., Lackner, K., Strom, T.M., Meitinger, T., Müller, T., Ohtake, A., Hoffmann, G.F., Prokisch, H., Staufner, C. (2016) Biallelic IARS Mutations Cause Growth Retardation with Prenatal Onset, Intellectual Disability, Muscular Hypotonia, and Infantile Hepatopathy. American journal of human genetics. 99(2):414-22

Beretta, C.A., Dross, N., Engel, U., Carl, M. (2016) Tracking Cells in GFP-transgenic Zebrafish Using the Photoconvertible PSmOrange System. Journal of visualized experiments : JoVE. (108):e53604

Hüsken, U., Stickney, H.L., Gestri, G., Bianco, I.H., Faro, A., Young, R.M., Roussigne, M., Hawkins, T.A., Beretta, C.A., Brinkmann, I., Paolini, A., Jacinto, R., Albadri, S., Dreosti, E., Tsalavouta, M., Schwarz, Q., Cavodeassi, F., Barth, A.K., Wen, L., Zhang, B., Blader, P., Yaksi, E., Poggi, L., Zigman, M., Lin, S., Wilson, S.W., Carl, M. (2014) Tcf7l2 Is Required for Left-Right Asymmetric Differentiation of Habenular Neurons. Current biology : CB. 24(19):2217-27

Dreosti, E., Vendrell Llopis, N., Carl, M., Yaksi, E., and Wilson, S.W. (2014) Left-right asymmetry is required for the habenulae to respond to both visual and olfactory stimuli. Current biology : CB. 24(4):440-445

Mwafi, N., Beretta, C.A., Paolini, A., and Carl, M. (2014) Divergent Wnt8a gene expression in teleosts. PLoS One. 9(1):e85303

Demir, K., Kirsch, N., Beretta, C.A., Erdmann, G., Ingelfinger, D., Moro, E., Argenton, F., Carl, M., Niehrs, C., and Boutros, M. (2013) RAB8B is required for activity and caveolar endocytosis of LRP6. Cell Reports. 4(6):1224-1234

Beretta, C.A., Dross, N., Bankhead, P., and Carl, M. (2013) The ventral habenulae of zebrafish develop in prosomere 2 dependent on Tcf7l2 function. Neural Development. 8(1):19

Hüsken, U., and Carl, M. (2013) The Wnt/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality. Mechanisms of Development. 130(6-8):330-5

McNabb, A., Scott, K., Ochsenstein, E.V., Seufert, K., and Carl, M. (2012) Don't be afraid to set up your fish facility. Zebrafish. 9(3):120-125

Beretta, C.A., Dross, N., Guiterrez-Triana, J.A., Ryu, S., and Carl, M. (2012) Habenula circuit development: past, present, and future. Frontiers in Neurogenesis. 6:51

Berns, N., Woichansky, I., Kraft, N., Hüsken, U., Carl, M., and Riechmann, V. (2012) "Vacuum-assisted staining": a simple and efficient method for screening in Drosophila. Development genes and evolution. 222(2):113-118

Beretta, C.A., Brinkmann, I., and Carl, M. (2011) All four zebrafish Wnt7 genes are expressed during early brain development. Gene expression patterns : GEP. 11(3-4):277-84

Wilkinson, C.J., Carl, M., and Harris, W.A. (2009) Cep70 and Cep131 contribute to ciliogenesis in zebrafish embryos. BMC Cell Biology. 10:17

Bianco, I.H., Carl, M., Russell, C., Clarke, J.D., and Wilson, S.W. (2008) Brain asymmetry is encoded at the level of axon terminal morphology. Neural Development. 3:9

Carl, M., Bianco, I.H., Bajoghli, B., Aghaallaei, N., Czerny, T., and Wilson, S.W. (2007) Wnt/Axin1/beta-Catenin Signaling Regulates Asymmetric Nodal Activation, Elaboration, and Concordance of CNS Asymmetries. Neuron. 55(3):393-405

Yokoi, H., Shimada, A., Carl, M., Takashima, S., Kobayashi, D., Narita, T., Jindo, T., Kimura, T., Kitagawa, T., Kage, T., Sawada, A., Naruse, K., Asakawa, S., Shimizu, N., Mitani, H., Shima, A., Tsutsumi, M., Hori, H., Wittbrodt, J., Saga, Y., Ishikawa, Y., Araki, K., and Takeda, H. (2007) Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships. Developmental Biology. 304(1):326-337

Gestri, G., Carl, M., Appolloni, I., Wilson, S.W., Barsacchi, G., and Andreazzoli, M. (2005) Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression. Development (Cambridge, England). 132(10):2401-2413

NON-ZEBRAFISH PUBLICATIONS
Hochmann, S., Aghaallaei, N., Bajoghli, B., Soroldoni, D., Carl, M., and Czerny, T. (2007) Expression of marker genes during early ear development in medaka. Gene Expr. Patterns. 7(3):355-362

Watanabe, T., Asaka, S., Kitagawa, D., Saito, K., Kurashige, R., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Henrich, T., Hirose, Y., Yasuoka, A., Yoda, H., Deguchi, T., Iwanami, N., Kunimatsu, S., Osakada, M., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Wittbrodt, J., Abe, K., Takahama, Y., Takahashi, K., Katada, T., Nishina, H., Kondoh, H., and Furutani-Seiki, M. (2004) Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria. Mech. Dev.. 121(7-8):791-802

Loosli, F., Bene, F.D., Quiring, R., Rembold, M., Martinez-Morales, J.R., Carl, M., Grabher, C., Iquel, C., Krone, A., Wittbrodt, B., Winkler, S., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Henrich, T., Deguchi, T., Hirose, Y., Iwanami, N., Kunimatsu, S., Osakada, M., Watanabe, T., Yasuoka, A., Yoda, H., Winkler, C., Elmasri, H., Kondoh, H., Furutani-Seiki, M., and Wittbrodt, J. (2004) Mutations affecting retina development in Medaka. Mech. Dev.. 121(7-8):703-714

Kitagawa, D., Watanabe, T., Saito, K., Asaka, S., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Yasuoka, A., Deguchi, T., Yoda, H., Hirose, Y., Henrich, T., Iwanami, N., Kunimatsu, S., Osakada, M., Winkler, C., Elmasri, H., Wittbrodt, J., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Momoi, A., Katada, T., Nishina, H., Kondoh, H., and Furutani-Seiki, M. (2004) Genetic dissection of the formation of the forebrain in Medaka, Oryzias latipes. Mech. Dev.. 121(7-8):673-685

Elmasri, H., Winkler, C., Liedtke, D., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Henrich, T., Hirose, Y., Yasuoka, A., Yoda, H., Watanabe, T., Deguchi, T., Iwanami, N., Kunimatsu, S., Osakada, M., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Wittbrodt, J., Abe, K., Takahama, Y., Takahashi, K., Katada, T., Nishina, H., Kondoh, H., and Furutani-Seiki, M. (2004) Mutations affecting somite formation in the Medaka (Oryzias latipes). Mech. Dev.. 121(7-8):659-671

Furutani-Seiki, M., Sasado, T., Morinaga, C., Suwa, H., Niwa, K., Yoda, H., Deguchi, T., Hirose, Y., Yasuoka, A., Henrich, T., Watanabe, T., Iwanami, N., Kitagawa, D., Saito, K., Asaka, S., Osakada, M., Kunimatsu, S., Momoi, A., Elmasri, H., Winkler, C., Ramialison, M., Loosli, F., Quiring, R., Carl, M., Grabher, C., Winkler, S., Del Bene, F., Shinomiya, A., Kota, Y., Yamanaka, T., Okamoto, Y., Takahashi, K., Todo, T., Abe, K., Takahama, Y., Tanaka, M., Mitani, H., Katada, T., Nishina, H., Nakajima, N., Wittbrodt, J., and Kondoh, H. (2004) A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech. Dev.. 121(7-8):647-658

Carl, M., Loosli, F., Wittbrodt, J. (2002). Six3 inactivation reveals its essential role for the formation and patterning of the vertebrate eye. Development, 129, 4057-4063.

Poggi, L., Carl, M., Vignali, R., Barsacchi, G., Wittbrodt, J. (2002). Expression of a medaka (Oryzias latipes) Bar homologue in the differentiating central nervous system and retina. Mech. Dev., 114, 193-196.

Loosli, F., Winkler, S., Burgtorf, C., Wurmbach, E., Ansorge, W., Henrich, T., Grabher, C., Arendt, D., Carl, M., Krone, A., Grzebisz, E., and Wittbrodt, J. (2001) Medaka eyeless is the key factor linking retinal determination and eye growth. Development. 128(20):4035-4044

Loosli, F., Köster, R. W., Carl, M., Kühnlein, R., Henrich, H., Mücke, M., Krone, A., Wittbrodt, J. (2000). A genetic screen for mutations affecting embryonic development in medaka fish (Oryzias latipes). Mech. Dev., 97, 133-139.

Carl, M., and Wittbrodt, J. (1999) Graded interference with FGF signalling reveals its dorsoventral asymmetry at the mid-hindbrain boundary. Development. 126(24):5659-5667

Ristoratore, F., Carl, M., Deschet, K., Richard-Parpaillon, L., Boujard, D., Wittbrodt, J., Chourrout, D., Bourrat, F., and Joly, J.S. (1999) The midbrain-hindbrain boundary genetic cascade is activated ectopically in the diencephalon in response to the widespread expression of one of its components, the medaka gene Ol-eng2. Development. 126(17):3769-3779

Loosli, F., Köster, R.W., Carl, M., Krone, A., Wittbrodt, J. (1998). Six3, a medaka homologue of the Drosophila homeobox gene sine oculis is expressed in the anterior embryonic shield and the developing eye. Mech. Dev., 74, 159-164.