ZFIN ID: ZDB-PERS-970313-8
Begemann, Gerrit
Email: gerrit.begemann@uni-bayreuth.de
URL: http://www.entwicklungsbiologie.uni-bayreuth.de/en/index.html
Affiliation: Begemann Lab
Address: Department of Animal Physiology University of Bayreuth Universitaetstrasse 30 Bayreuth, D-95440 Germany
Country: Germany
Phone: 49-921-552475
Fax: 49-921-552794
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Schleser, S.W., Köhler, L.H.F., Riethmüller, F., Reich, S., Fertig, R., Schlotte, L., Seib, J., Goller, A., Begemann, G., Kempe, R., Schobert, R. (2023) Anti-tumoural [NHC(thiolato)]Au(I) complexes derived from HIF-1α inhibitor AC1-004 target the mitochondrial redox system and show antiangiogenic effects in vivo. ChemPlusChem. 88(5):e202300167
Köhler, L.H.F., Reich, S., Yusenko, M., Klempnauer, K.H., Begemann, G., Schobert, R., Biersack, B. (2023) Multimodal 4-arylchromene derivatives with microtubule-destabilizing, anti-angiogenic, and MYB-inhibitory activities. Cancer drug resistance (Alhambra, Calif.). 6:597759-77
Zhouyao, H., Zimmer, A.M., Fehsenfeld, S., Liebenstein, T., Richter, D.O., Begemann, G., Eck, P., Perry, S.F., Weihrauch, D. (2022) Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio. The Journal of experimental biology. 225(20):
Schmitt, F., Kasparkova, J., Brabec, V., Begemann, G., Schobert, R., Biersack, B. (2018) New (arene)ruthenium(II) complexes of 4‑aryl‑4H‑naphthopyrans with anticancer and anti-vascular activities. Journal of inorganic biochemistry. 184:69-78
Schmitt, F., Gold, M., Begemann, G., Andronache, I., Biersack, B., Schobert, R. (2017) Fluoro and pentafluorothio analogs of the antitumoral curcuminoid EF24 with superior antiangiogenic and vascular-disruptive effects. Bioorganic & Medicinal Chemistry. 25(17):4894-4903
Draut, H., Rehm, T., Begemann, G., Schobert, R. (2017) Antiangiogenic and toxic effects of genistein, usnic acid, and their copper complexes in zebrafish embryos at different developmental stages. Chemistry & biodiversity. 14(3):e1600302
Blum, N., Begemann, G. (2015) Retinoic acid signaling spatially restricts osteoblasts and controls ray-interray organization during zebrafish fin regeneration. Development (Cambridge, England). 142(17):2888-93
Blum, N., Begemann, G. (2015) Osteoblast de- and redifferentiation is controlled by a dynamic response to retinoic acid during zebrafish fin regeneration. Development (Cambridge, England). 142(17):2894-903
Pittlik, S., and Begemann, G. (2012) New sources of retinoic acid synthesis revealed by live imaging of an Aldh1a2-GFP reporter fusion protein throughout zebrafish development. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(7):1205-1216
Blum, N., and Begemann, G. (2012) Retinoic acid signaling controls the formation, proliferation and survival of the blastema during adult zebrafish fin regeneration. Development (Cambridge, England). 139(1):107-16
Manousaki, T., Feiner, N., Begemann, G., Meyer, A., and Kuraku, S. (2011) Co-orthology of Pax4 and Pax6 to the fly eyeless gene: molecular phylogenetic, comparative genomic, and embryological analyses. Evolution & development. 13(5):448-459
Kikuchi, K., Holdway, J.E., Major, R.J., Blum, N., Dahn, R.D., Begemann, G., and Poss, K.D. (2011) Retinoic Acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. Developmental Cell. 20(3):397-404
Begemann, G. (2011) Literature review and commentary. Zebrafish. 8(1):35-38
Gibert, Y., Bernard, L., Debiais-Thibaud, M., Bourrat, F., Joly, J.S., Pottin, K., Meyer, A., Retaux, S., Stock, D.W., Jackman, W.R., Seritrakul, P., Begemann, G., and Laudet, V. (2010) Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(9):3298-3309
Begemann, G. (2010) Literature Review and Commentary. Zebrafish. 7(1):119-121
Feiner, N., Begemann, G., Renz, A.J., Meyer, A., and Kuraku, S. (2009) The origin of bmp16, a novel Bmp2/4 relative, retained in teleost fish genomes. BMC Evolutionary Biology. 9:277
Pittlik, S., Domingues, S., Meyer, A., and Begemann, G. (2008) Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts. Gene expression patterns : GEP. 8(3):141-147
Begemann, G. (2008) MicroRNAs and RNA interference in zebrafish development. Zebrafish. 5(2):111-119
Aleström, P., Begemann, G., Carvan, M.J. 3rd, Cheng, K.C., Crosier, K., Crosier, P., Ekker, S., Huttenlocher, A., Kawakami, K., Kelly, G., Korzh, V., Lieschke, G., Mione, M., Neely, M.N., Neuhauss, S., and Trede, N.S. (2008) Views on four key questions about zebrafish research. Zebrafish. 5(1):9-24
Gibert, Y., Gajewski, A., Meyer, A., and Begemann, G. (2006) Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling. Development (Cambridge, England). 133(14):2649-2659
Hamade, A., Deries, M., Begemann, G., Bally-Cuif, L., Genet, C., Sabatier, F., Bonnieu, A., and Cousin, X. (2006) Retinoic acid activates myogenesis in vivo through Fgf8 signalling. Developmental Biology. 289(1):127-140
Gu, W., Gibert, Y., Wirth, T., Elischer, A., Bloch, W., Meyer, A., Steinlein, O.K., and Begemann, G. (2005) Using Gene-History and Expression Analyses to Assess the Involvement of LGI Genes in Human Disorders. Mol. Biol. Evol.. 22(11):2209-2216
Gibert, Y., McMillan, D.R., Kayes-Wandover, K., Meyer, A., Begemann, G., and White, P.C. (2005) Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish. Gene. 353(2):200-206
Keegan, B.R., Feldman, J.L., Begemann, G., Ingham, P.W., and Yelon, D. (2005) Retinoic acid signaling restricts the cardiac progenitor pool. Science (New York, N.Y.). 307(5707):247-249
Begemann, G., Marx, M., Mebus, K., Meyer, A., and Bastmeyer, M. (2004) Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain. Developmental Biology. 271(1):119-129
Begemann, G., Gibert, Y., Meyer, A., and Ingham, P.W. (2002) Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development. Mechanisms of Development. 114(1-2):137
Begemann, G., Schilling, T.F., Rauch, G.J., Geisler, R., and Ingham, P.W. (2001) The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development (Cambridge, England). 128(16):3081-3094
Begemann, G. and Ingham, P.W. (2000) Developmental regulation of Tbx5 in zebrafish embryogenesis. Mechanisms of Development. 90(2):299-304

NON-ZEBRAFISH PUBLICATIONS
Zauner H, Begemann G, Mari-Beffa M, Meyer A. (2003) Differential regulation of msx genes in the development of the gonopodium, an intromittent organ, and of the "sword," a sexually selected trait of swordtail fishes (Xiphophorus). Evol Dev. 2003 Sep-Oct;5(5):466-77.

Begemann, G. and Meyer, A. (2001). Hindbrain patterning revisited: timing and effects of retinoic acid signalling. Bioessays 23:981-6. Review

Artero R, Prokop A, Paricio N, Begemann G, Pueyo I, Mlodzik M, Perez-Alonso M, Baylies MK(1998). The muscleblind gene participates in the organization of Z-bands and epidermal attachments of Drosophila muscles and is regulated by Dmef2. Dev Biol. 195:131-43.

Begemann G, Paricio N, Artero R, Kiss I, Perez-Alonso M, Mlodzik M. (1997). muscleblind, a gene required for photoreceptor differentiation in Drosophila, encodes novel nuclear Cys3His-type zinc-finger-containing proteins. Development 124:4321-31.

Begemann G, Michon AM, vd Voorn L, Wepf R, Mlodzik M. (1995). The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination. Development 121:225-35.