ZFIN Person: Leung, Tin Chung

ZFIN ID: ZDB-PERS-970313-41

Leung, Tin Chung

Email:	tleung@nccu.edu
URL:
Affiliation:
Address:	Julius L. Chambers Biomedical Biotechnology Research Institute North Carolina Central University North Carolina Research Campus Rm 4302, Nutrition Research Center 500 Laureate Way Kannapolis, NC 28081
Country:
Phone:	(704) 250-5728
Fax:	(704) 250-5727
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Gadi, S., Niture, S., Hoang, H., Qi, Q., Hatcher, C., Huang, X., Haider, J., Norford, D.C., Leung, T., Levine, K.E., Kumar, D. (2023) Deficiency of spns1 Exacerbates Per- and Polyfluoroalkyl Substances Mediated Hepatic Toxicity and Steatosis in Zebrafish (Danio rerio). Toxicology. 499:153641

Onyenwoke, R.U., Leung, T., Huang, X., Parker, D., Shipman, J.G., Alhadyan, S.K., Sivaraman, V. (2022) An assessment of vaping-induced inflammation and toxicity: A feasibility study using a 2-stage zebrafish and mouse platform. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 163:112923

Dong, W., Han, X., Bao, C., Tai, S., Bai, Y., Xu, L., Yang, J., Leung, T., Ao, W., Dong, W. (2021) Inhibitory Effects of Euphorbia ebracteolata Hayata Extract ECB on Melanoma-Induced Hyperplasia of Blood Vessels in Zebrafish Embryos. Evidence-based complementary and alternative medicine : eCAM. 2021:5543259

Li, Y., Zhao, Y., Sang, S., Leung, T. (2019) Methylglyoxal-Induced Retinal Angiogenesis in Zebrafish Embryo: A Potential Animal Model of Neovascular Retinopathy. Journal of ophthalmology. 2019:2746735

Ferri-Lagneau, K.F., Haider, J., Sang, S., Leung, T. (2019) Rescue of hematopoietic stem/progenitor cells formation in plcg1 zebrafish mutant. Scientific Reports. 9:244

Zhou, R., Curry, J.M., Roy, L.D., Grover, P., Haider, J., Moore, L.J., Wu, S.T., Kamesh, A., Yazdanifar, M., Ahrens, W.A., Leung, T., Mukherjee, P. (2016) A novel association of neuropilin-1 and MUC1 in pancreatic ductal adenocarcinoma: role in induction of VEGF signaling and angiogenesis. Oncogene. 35(43):5608-5618

Zhu, Y., Wang, P., Zhao, Y., Yang, C., Clark, A., Leung, T., Chen, X., Sang, S. (2016) Synthesis, Evaluation, and Metabolism of Novel [6]-Shogaol Derivatives as Potent Nrf2 Activators. Free radical biology & medicine. 95:243-54

Chen, H., Soroka, D.N., Haider, J., Ferri-Lagneau, K.F., Leung, T., and Sang, S. (2013) [10]-Gingerdiols as the Major Metabolites of [10]-Gingerol in Zebrafish Embryos and in Humans and Their Hematopoietic Effects in Zebrafish Embryos. Journal of Agricultural and Food Chemistry. 61(22):5353-60

Ferri-Lagneau, K.F., Moshal, K.S., Grimes, M., Zahora, B., Lv, L., Sang, S., and Leung, T. (2012) Ginger Stimulates Hematopoiesis via Bmp Pathway in Zebrafish. PLoS One. 7(6):e39327

Moshal, K.S., Ferri-Lagneau, K.F., Haider, J., Pardhanani, P., and Leung, T. (2011) Discriminating Different Cancer Cells Using a Zebrafish in Vivo Assay. Cancers. 3(4):4102–4113

Leung, T., Humbert, J.E., Stauffer, A.M., Giger, K.E., Chen, H., Tsai, H.J., Wang, C., Mirshahi, T., and Robishaw, J.D. (2008) The orphan G protein-coupled receptor 161 is required for left-right patterning. Developmental Biology. 323(1):31-40

Chen, H., Leung, T., Giger, K.E., Stauffer, A.M., Humbert, J.E., Sinha, S., Horstick, E.J., Hansen, C.A., and Robishaw, J.D. (2007) Expression of the G protein gammaT1 subunit during zebrafish development. Gene expression patterns : GEP. 7(5):574-583

Leung, T., Chen, H., Stauffer, A.M., Giger, K.E., Sinha, S., Horstick, E.J., Humbert, J.E., Hansen, C.A., and Robishaw, J.D. (2006) Zebrafish G protein γ2 is required for VEGF signaling during angiogenesis. Blood. 108(1):160-166

Leung, T., Söll, I., Arnold, S.J., Kemler, R., and Driever, W. (2003) Direct binding of Lef1 to sites in the boz promoter may mediate pre-midblastula-transition activation of boz expression. Developmental Dynamics : an official publication of the American Association of Anatomists. 228(3):424-432

Leung, T., Bischof, J., Söll, I., Niessing, D., Zhang, D., Ma, J., Jäckle, H., and Driever, W. (2003) bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish. Development (Cambridge, England). 130(16):3639-3649

Doitsidou, M., Reichman-Fried, M., Stebler, J., Köprunner, M., Dörries, J., Meyer, D., Esguerra, C.V., Leung, T., and Raz, E. (2002) Guidance of primordial germ cell migration by the chemokine SDF-1. Cell. 111(5):647-659

Fekany, K., Yamanaka, Y., Leung, T., Sirotkin, H.I., Topczewski, J., Gates, M.A., Hibi, M., Renucci, A., Stemple, D., Radbill, A., Schier, A.F., Driever, W., Hirano, T., Talbot, W.S., and Solnica-Krezel, L. (1999) The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development (Cambridge, England). 126:1427-1438

NON-ZEBRAFISH PUBLICATIONS