ZFIN Person: Braunbeck, Thomas

ZFIN ID: ZDB-PERS-970303-2

Braunbeck, Thomas

Email:	braunbeck@urz.uni-heidelberg.de
URL:	https://www.cos.uni-heidelberg.de/index.php/t.braunbeck?l=_e
Affiliation:
Address:	Department of Zoology I University of Heidelberg Im Neuenheimer Feld 230 Heidelberg, D-69120 Germany
Country:
Phone:	49-6221-545668 or 49-6221-545656
Fax:	49-6221-546162
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Kämmer, N., Reimann, T., Braunbeck, T. (2024) Neurotoxic pesticides change respiratory parameters in early gill-breathing, but not in skin-breathing life-stages of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 267:106831106831

von Hellfeld, R., Gade, C., Baumann, L., Leist, M., Braunbeck, T. (2023) The sensitivity of the zebrafish embryo coiling assay for the detection of neurotoxicity by compounds with diverse modes of action. Environmental science and pollution research international. 30(30):75281-75299

Pannetier, P., Poulsen, R., Gölz, L., Coordes, S., Stegeman, H., Koegst, J., Reger, L., Braunbeck, T., Hansen, M., Baumann, L. (2023) Reversibility of thyroid hormone system-disrupting effects on eye and thyroid follicle development in zebrafish (Danio rerio) embryos. Environmental toxicology and chemistry. 42(6):1276-1292

Kämmer, N., Reimann, T., Ovcharova, V., Braunbeck, T. (2023) A novel automated method for the simultaneous detection of breathing frequency and amplitude in zebrafish (Danio rerio) embryos and larvae. Aquatic toxicology (Amsterdam, Netherlands). 258:106493106493

Kraft, M., Gölz, L., Rinderknecht, M., Koegst, J., Braunbeck, T., Baumann, L. (2022) Developmental exposure to triclosan and benzophenone-2 causes morphological alterations in zebrafish (Danio rerio) thyroid follicles and eyes. Environmental science and pollution research international. 30(12):33711-33724

Frese, L., Braunbeck, T. (2022) Adapting classic paradigms to analyze alterations of shoal-wide behavior in early-life stages of zebrafish (Danio rerio) - A case study with fluoxetine. Neurotoxicology and teratology. 95:107136

Gölz, L., Baumann, L., Pannetier, P., Braunbeck, T., Knapen, D., Vergauwen, L. (2022) AOP Report: Thyroperoxidase Inhibition Leading to Altered Visual Function in Fish via Altered Retinal Layer Structure. Environmental toxicology and chemistry. 41(11):2632-2648

Brotzmann, K., Escher, S.E., Walker, P., Braunbeck, T. (2022) Potential of the zebrafish (Danio rerio) embryo test to discriminate between chemicals of similar molecular structure-a study with valproic acid and 14 of its analogues. Archives of toxicology. 96(11):3033-3051

Kämmer, N., Erdinger, L., Braunbeck, T. (2022) The onset of active gill respiration in post-embryonic zebrafish (Danio rerio) larvae triggers an increased sensitivity to neurotoxic compounds. Aquatic toxicology (Amsterdam, Netherlands). 249:106240

Von Hellfeld, R., Ovcharova, V., Bevan, S., Lazaridi, M.A., Bauch, C., Walker, P., Hougaard Bennekou, S., Forsby, A., Braunbeck, T. (2022) Zebrafish embryo neonicotinoid developmental neurotoxicity in the FET test and behavioral assays. Altex. 39(3):367–387

Hanslik, L., Seiwert, B., Huppertsberg, S., Knepper, T.P., Reemtsma, T., Braunbeck, T. (2022) Biomarker responses in zebrafish (Danio rerio) following long-term exposure to microplastic-associated chlorpyrifos and benzo(k)fluoranthene. Aquatic toxicology (Amsterdam, Netherlands). 245:106120

Hanslik, L., Huppertsberg, S., Kämmer, N., Knepper, T.P., Braunbeck, T. (2021) Rethinking the relevance of microplastics as vector for anthropogenic contaminants: Adsorption of toxicants to microplastics during exposure in a highly polluted stream - Analytical quantification and assessment of toxic effects in zebrafish (Danio rerio). The Science of the total environment. 816:151640

von Hellfeld, R., Pannetier, P., Braunbeck, T. (2021) Specificity of time- and dose-dependent morphological endpoints in the fish embryo acute toxicity (FET) test for substances with diverse modes of action: the search for a "fingerprint". Environmental science and pollution research international. 29(11):16176-16192

Loerracher, A.K., Braunbeck, T. (2021) Cytochrome P450-dependent biotransformation capacities in embryonic, juvenile and adult stages of zebrafish (Danio rerio)-a state-of-the-art review. Archives of toxicology. 95(7):2299-2334

Teixeira, T.M., Arraes, I.G., Abreu, D.C., Oliveira, K.M., Correa, R.S., Batista, A.A., Braunbeck, T., de Paula Silveira Lacerda, E. (2021) Ruthenium complexes show promise when submitted to toxicological safety tests using alternative methodologies. European Journal of Medicinal Chemistry. 216:113262

Siméon, S., Beaudouin, R., Brotzmann, K., Braunbeck, T., Bois, F.Y. (2021) Multistate models of developmental toxicity: Application to valproic acid-induced malformations in the zebrafish embryo. Toxicology and applied pharmacology. 414:115424

Brotzmann, K., Wolterbeek, A., Kroese, D., Braunbeck, T. (2020) Neurotoxic effects in zebrafish embryos by valproic acid and nine of its analogues: the fish-mouse connection?. Archives of toxicology. 95(2):641-657

Cousin, X., Batel, A., Bringer, A., Hess, S., Bégout, M.L., Braunbeck, T. (2020) Microplastics and sorbed contaminants - Trophic exposure in fish sensitive early life stages. Marine Environmental Research. 161:105126

Hanslik, L., Sommer, C., Huppertsberg, S., Dittmar, S., Knepper, T.P., Braunbeck, T. (2020) Microplastic-associated trophic transfer of benzo(k)fluoranthene in a limnic food web: Effects in two freshwater invertebrates (Daphnia magna, Chironomus riparius) and zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 237:108849

Zindler, F., Stoll, S., Baumann, L., Knoll, S., Huhn, C., Braunbeck, T. (2020) Do environmentally relevant concentrations of fluoxetine and citalopram impair stress-related behavior in zebrafish (Danio rerio) embryos?. Chemosphere. 261:127753

Knoll, S., Jacob, S., Mieck, S., Triebskorn, R., Braunbeck, T., Huhn, C. (2020) Development of a capillary electrophoresis-mass spectrometry method for the analysis of metformin and its transformation product guanylurea in biota. Analytical and bioanalytical chemistry. 412(20):4985-4996

Loerracher, A.K., Braunbeck, T. (2020) Inducibility of cytochrome P450-mediated 7-methoxycoumarin-O-demethylase activity in zebrafish (Danio rerio) embryos. Aquatic toxicology (Amsterdam, Netherlands). 225:105540

Batel, A., Baumann, L., Carteny, C.C., Cormier, B., Keiter, S.H., Braunbeck, T. (2020) Histological, enzymatic and chemical analyses of the potential effects of differently sized microplastic particles upon long-term ingestion in zebrafish (Danio rerio). Marine pollution bulletin. 153:111022

Zindler, F., Tisler, S., Loerracher, A.K., Zwiener, C., Braunbeck, T. (2020) Norfluoxetine Is the Only Metabolite of Fluoxetine in Zebrafish (Danio rerio) Embryos That Accumulates at Environmentally Relevant Exposure Scenarios. Environmental science & technology. 54(7):4200-4209

Siméon, S., Brotzmann, K., Fisher, C., Gardner, I., Silvester, S., Maclennan, R., Walker, P., Braunbeck, T., Bois, F.Y. (2020) Development of a generic zebrafish embryo PBPK model and application to the developmental toxicity assessment of valproic acid analogs. Reproductive toxicology (Elmsford, N.Y.). 93:219-229

Loerracher, A.K., Grethlein, M., Braunbeck, T. (2020) In vivo fluorescence-based characterization of cytochrome P450 activity during embryonic development of zebrafish (Danio rerio). Ecotoxicology and environmental safety. 192:110330

Zindler, F., Beedgen, F., Brandt, D., Steiner, M., Stengel, D., Baumann, L., Braunbeck, T. (2019) Analysis of tail coiling activity of zebrafish (Danio rerio) embryos allows for the differentiation of neurotoxicants with different modes of action. Ecotoxicology and environmental safety. 186:109754

Baumann, L., Holbech, H., Schmidt-Posthaus, H., Moissl, A.P., Hennies, M., Tiedemann, J., Weltje, L., Segner, H., Braunbeck, T. (2019) Does hepatotoxicity interfere with endocrine activity in zebrafish (Danio rerio)?. Chemosphere. 238:124589

du Plessis, B., Regnier, T., Combrinck, S., Heinrich, P., Braunbeck, T. (2019) Effect of pH on the toxicity of fumonisins towards the RTL-W1 cell line and zebrafish (Danio rerio) embryos. Toxicology letters. 313:101-107

Zindler, F., Beedgen, F., Braunbeck, T. (2019) Time-course of coiling activity in zebrafish (Danio rerio) embryos exposed to ethanol as an endpoint for developmental neurotoxicity (DNT) - Hidden potential and underestimated challenges. Chemosphere. 235:12-20

Tisler, S., Zindler, F., Freeling, F., Nödler, K., Toelgyesi, L., Braunbeck, T., Zwiener, C. (2019) Transformation products of fluoxetine formed by photodegradation in water and biodegradation in zebrafish embryos (Danio rerio). Environmental science & technology. 53(13):7400-7409

Zhao, H., Di Mauro, G., Lungu-Mitea, S., Negrini, P., Guarino, A.M., Frigato, E., Braunbeck, T., Ma, H., Lamparter, T., Vallone, D., Bertolucci, C., Foulkes, N.S. (2018) Modulation of DNA Repair Systems in Blind Cavefish during Evolution in Constant Darkness. Current biology : CB. 28(20):3229-3243.e4

Heinrich, P., Braunbeck, T. (2018) Genetically engineered zebrafish liver (ZF-L) cells as an in vitro source for zebrafish acetylcholinesterase (zfAChE) for the use in AChE inhibition assays. Toxicology in vitro : an international journal published in association with BIBRA. 52:52-59

Batel, A., Borchert, F., Reinwald, H., Erdinger, L., Braunbeck, T. (2018) Microplastic accumulation patterns and transfer of benzo[a]pyrene to adult zebrafish (Danio rerio) gills and zebrafish embryos. Environmental pollution (Barking, Essex : 1987). 235:918-930

Rehberger, K., Baumann, L., Hecker, M., Braunbeck, T. (2018) Intrafollicular thyroid hormone staining in whole-mount zebrafish (Danio rerio) embryos for the detection of thyroid hormone synthesis disruption. Fish physiology and biochemistry. 44(3):997-1010

Kais, B., Ottermanns, R., Scheller, F., Braunbeck, T. (2018) Modification and quantification of in vivo EROD live-imaging with zebrafish (Danio rerio) embryos to detect both induction and inhibition of CYP1A. The Science of the total environment. 615:330-347

Boehler, S., Lörracher, A.K., Schubert, J., Braunbeck, T. (2017) Comparative live-imaging of in vivo EROD (ethoxyresorufin-O-deethylase) induction in zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) embryos after exposure to PAHs and river sediment extracts. The Science of the total environment. 621:827-838

Stengel, D., Wahby, S., Braunbeck, T. (2017) In search of a comprehensible set of endpoints for the routine monitoring of neurotoxicity in vertebrates: sensory perception and nerve transmission in zebrafish (Danio rerio) embryos. Environmental science and pollution research international. 25(5):4066-4084

Boehler, S., Strecker, R., Heinrich, P., Prochazka, E., Northcott, G.L., Ataria, J.M., Leusch, F.D., Braunbeck, T., Tremblay, L.A. (2017) Assessment of urban stream sediment pollutants entering estuaries using chemical analysis and multiple bioassays to characterise biological activities. The Science of the total environment. 593-594:498-507

Kais, B., Schiwy, S., Hollert, H., Keiter, S.H., Braunbeck, T. (2017) In vivo EROD assays with the zebrafish (Danio rerio) as rapid screening tools for the detection of dioxin-like activity. The Science of the total environment. 590-591:269-280

Schmidt, F., Wolf, R., Baumann, L., Braunbeck, T. (2017) Ultrastructural Alterations in Thyrocytes of Zebrafish ( Danio rerio) after Exposure to Propylthiouracil and Perchlorate. Toxicologic pathology. 45:649-662

Pelka, K.E., Henn, K., Keck, A., Sapel, B., Braunbeck, T. (2017) Size does matter - Determination of the critical molecular size for the uptake of chemicals across the chorion of zebrafish (Danio rerio) embryos. Aquatic toxicology (Amsterdam, Netherlands). 185:1-10

Stengel, D., Zindler, F., Braunbeck, T. (2017) An optimized method to assess ototoxic effects in the lateral line of zebrafish (Danio rerio) embryos. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 193:18-29

Batel, A., Linti, F., Scherer, M., Erdinger, L., Braunbeck, T. (2016) The transfer of benzo[a]pyrene from microplastics to Artemia nauplii and further to zebrafish via a trophic food web experiment - CYP1A induction and visual tracking of persistent organic pollutants. Environmental toxicology and chemistry. 35(7):1656-66

Keiter, S., Burkhard-Medicke, K., Wellner, P., Kais, B., Färber, H., Skutlarek, D., Engwall, M., Braunbeck, T., Keiter, S.H., Luckenbach, T. (2016) Does perfluorooctane sulfonate (PFOS) act as chemosensitizer in zebrafish embryos?. The Science of the total environment. 548-549:317-324

Baumann, L., Knörr, S., Keiter, S., Nagel, T., Segner, H., Braunbeck, T. (2015) Prochloraz causes irreversible masculinization of zebrafish (Danio rerio). Environmental science and pollution research international. 22(21):16417-22

Kais, B., Stengel, D., Batel, A., Braunbeck, T. (2015) Erratum to: Acetylcholinesterase in zebrafish embryos as a tool to identify neurotoxic effects in sediments. Environmental science and pollution research international. 22(21):16340

Kais, B., Stengel, D., Batel, A., Braunbeck, T. (2015) Acetylcholinesterase in zebrafish embryos as a tool to identify neurotoxic effects in sediments. Environmental science and pollution research international. 22(21):16329-39

Braunbeck, T., Kais, B., Lammer, E., Otte, J., Schneider, K., Stengel, D., Strecker, R. (2015) The fish embryo test (FET): origin, applications, and future. Environmental science and pollution research international. 22(21):16247-61

Schulze, T., Ulrich, M., Maier, D., Maier, M., Terytze, K., Braunbeck, T., Hollert, H. (2015) Evaluation of the hazard potentials of river suspended particulate matter and floodplain soils in the Rhine basin using chemical analysis and in vitro bioassays. Environmental science and pollution research international. 22(19):14606-20

Baumann, L., Knörr, S., Keiter, S., Nagel, T., Rehberger, K., Volz, S., Oberrauch, S., Schiller, V., Fenske, M., Holbech, H., Segner, H., Braunbeck, T. (2014) Persistence of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the androgen 17β-trenbolone. Environmental toxicology and chemistry. 33(11):2488-96

Seiler, T.B., Best, N., Fernqvist, M.M., Hercht, H., Smith, K.E., Braunbeck, T., Mayer, P., Hollert, H. (2014) PAH toxicity at aqueous solubility in the fish embryo test with Danio rerio using passive dosing. Chemosphere. 112C:77-84

Bluhm, K., Otte, J.C., Yang, L., Zinsmeister, C., Legradi, J., Keiter, S., Kosmehl, T., Braunbeck, T., Strähle, U., Hollert, H. (2014) Impacts of Different Exposure Scenarios on Transcript Abundances in Danio rerio Embryos when Investigating the Toxicological Burden of Riverine Sediments. PLoS One. 9:e106523

Baumann, L., Knörr, S., Keiter, S., Rehberger, K., Volz, S., Schiller, V., Fenske, M., Holbech, H., Segner, H., Braunbeck, T. (2014) Reversibility of endocrine disruption in zebrafish (Danio rerio) after discontinued exposure to the estrogen 17α-ethinylestradiol. Toxicology and applied pharmacology. 278(3):230-7

Busquet, F., Strecker, R., Rawlings, J.M., Belanger, S.E., Braunbeck, T., Carr, G.J., Cenijn, P., Fochtman, P., Gourmelon, A., Hübler, N., Kleensang, A., Knöbel, M., Kussatz, C., Legler, J., Lillicrap, A., Martínez-Jerónimo, F., Polleichtner, C., Rzodeczko, H., Salinas, E., Schneider, K.E., Scholz, S., Brandhof, E.J., van der Ven, L.T., Walter-Rohde, S., Weigt, S., Witters, H., Halder, M. (2014) OECD validation study to assess intra- and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing. Regulatory toxicology and pharmacology : RTP. 69(3):496-511

Vincze, K., Gehring, M., Braunbeck, T. (2014) (Eco)toxicological effects of 2,4,7,9-tetramethyl-5-decyne-4,7-diol (TMDD) in zebrafish (Danio rerio) and permanent fish cell cultures. Environmental science and pollution research international. 21(13):8233-41

Kais, B., Schneider, K.E., Keiter, S., Henn, K., Ackermann, C., and Braunbeck, T. (2013) DMSO modifies the permeability of the zebrafish (Danio rerio) chorion-Implications for the fish embryo test (FET). Aquatic toxicology (Amsterdam, Netherlands). 140-141C:229-238

Faßbender, C., and Braunbeck, T. (2013) Reproductive and genotoxic effects in zebrafish after chronic exposure to methyl methanesulfonate in a multigeneration study. Ecotoxicology (London, England). 22(5):825-37

Faßbender, C., and Braunbeck, T. (2013) Assessment of Genotoxicity in Gonads, Liver and Gills of Zebrafish (Danio rerio) by Use of the Comet Assay and Micronucleus Test after In Vivo Exposure to Methyl Methanesulfonate. Bulletin of environmental contamination and toxicology. 91(1):89-95

Strecker, R., Weigt, S., and Braunbeck, T. (2013) Cartilage and bone malformations in the head of zebrafish (Danio rerio) embryos following exposure to disulfiram and acetic acid hydrazide. Toxicology and applied pharmacology. 268(2):221-231

Baumann, L., Holbech, H., Keiter, S., Kinnberg, K.L., Knörr, S., Nagel, T., and Braunbeck, T. (2013) The maturity index as a tool to facilitate the interpretation of changes in vitellogenin production and sex ratio in the Fish Sexual Development Test. Aquatic toxicology (Amsterdam, Netherlands). 128-129C:34-42

Keiter, S., Baumann, L., Färber, H., Holbech, H., Skutlarek, D., and Engwall, M., and Braunbeck, T. (2012) Long-term effects of a binary mixture of perfluorooctane sulfonate (PFOS) and bisphenol A (BPA) in zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 118-119C:116-129

Kosmehl, T., Otte, J.C., Yang, L., Legradi, J., Bluhm, K., Zinsmeister, C., Keiter, S.H., Reifferscheid, G., Manz, W., Braunbeck, T., Strähle, U., and Hollert, H. (2012) A combined DNA-microarray and mechanism-specific toxicity approach with zebrafish embryos to investigate the pollution of river sediments. Reproductive toxicology (Elmsford, N.Y.). 33(2):245-253

Strähle, U., Scholz, S., Geisler, R., Greiner, P., Hollert, H., Rastegar, S., Schumacher, A., Selderslaghs, I., Weiss, C., Witters, H., and Braunbeck, T. (2012) Zebrafish embryos as an alternative to animal experiments-A commentary on the definition of the onset of protected life stages in animal welfare regulations. Reproductive toxicology (Elmsford, N.Y.). 33(2):128-132

Weigt, S., Huebler, N., Strecker, R., Braunbeck, T., and Broschard, T.H. (2012) Developmental effects of coumarin and the anticoagulant coumarin derivative warfarin on zebrafish (Danio rerio) embryos. Reproductive toxicology (Elmsford, N.Y.). 33(2):133-141

Peddinghaus, S., Brinkmann, M., Bluhm, K., Sagner, A., Hinger, G., Braunbeck, T., Eisenträger, A., Tiehm, A., Hollertm, H., and Keiter, S.H. (2012) Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio). Reproductive toxicology (Elmsford, N.Y.). 33(2):224-232

Holbech, H., Kinnberg, K., Brande-Lavridsen, N., Bjerregaard, P., Petersen, G.I., Norrgren, L., Orn, S., Braunbeck, T., Baumann, L., Bomke, C., Dorgerloh, M., Bruns, E., Ruehl-Fehlert, C., Green, J.W., Springer, T.A., and Gourmelon, A. (2012) Comparison of zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) as test species in the Fish Sexual Development Test (FSDT). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 155(2):407-15

Schmidt, F., Schnurr, S., Wolf, R., and Braunbeck, T. (2012) Effects of the anti-thyroidal compound potassium-perchlorate on the thyroid system of the zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 109C:47-58

Boettcher, M., Kosmehl, T., and Braunbeck, T. (2011) Low-dose effects and biphasic effect profiles: Is trenbolone a genotoxicant?. Mutation research. 723(2):152-7

Osterauer, R., Faßbender, C., Braunbeck, T., and Köhler, H.R. (2011) Genotoxicity of platinum in embryos of zebrafish (Danio rerio) and ramshorn snail (Marisa cornuarietis). The Science of the total environment. 409(11):2114-2119

Strecker, R., Seiler, T.B., Hollert, H., and Braunbeck, T. (2011) Oxygen requirements of zebrafish (Danio rerio) embryos in embryo toxicity tests with environmental samples. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 153(3):318-327

Weigt, S., Huebler, N., Strecker, R., Braunbeck, T., and Broschard, T.H. (2011) Zebrafish (Danio rerio) embryos as a model for testing proteratogens. Toxicology. 281(1-3):25-36

Schmidt, F., and Braunbeck, T. (2011) Alterations along the Hypothalamic-Pituitary-Thyroid Axis of the Zebrafish (Danio rerio) after Exposure to Propylthiouracil. Journal of Thyroid Research. 2011:376243

Henn, K., and Braunbeck, T. (2011) Dechorionation as a tool to improve the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 153(1):91-98

Otte, J.C., Schmidt, A.D., Hollert, H., and Braunbeck, T. (2010) Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 100(1):38-50

Weigt, S., Huebler, N., Braunbeck, T., von Landenberg, F., and Broschard, T.H. (2010) Zebrafish teratogenicity test with metabolic activation (mDarT): Effects of phase I activation of acetaminophen on zebrafish Danio rerio embryos. Toxicology. 275(1-3):36-49

Embry, M.R., Belanger, S.E., Braunbeck, T.A., Galay-Burgos, M., Halder, M., Hinton, D.E., Léonard, M.A., Lillicrap, A., Norberg-King, T., and Whale, G. (2010) The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research. Aquatic toxicology (Amsterdam, Netherlands). 97(2):79-87

Lammer, E., Kamp, H.G., Hisgen, V., Koch, M., Reinhard, D., Salinas, E.R., Wendler, K., Zok, S., and Braunbeck, T. (2009) Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Toxicology in vitro : an international journal published in association with BIBRA. 23(7):1436-1442

Lammer, E., Carr, G.J., Wendler, K., Rawlings, J.M., Belanger, S.E., and Braunbeck, T. (2009) Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test?. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 149(2):196-209

Seitz, N., Böttcher, M., Keiter, S., Kosmehl, T., Manz, W., Hollert, H., and Braunbeck, T. (2008) A novel statistical approach for the evaluation of comet assay data. Mutation research. 652(1):38-45

Kosmehl, T., Hallare, A.V., Braunbeck, T., and Hollert, H. (2008) DNA damage induced by genotoxicants in zebrafish (Danio rerio) embryos after contact exposure to freeze-dried sediment and sediment extracts from Laguna Lake (The Philippines) as measured by the comet assay. Mutation research. 650(1):1-14

Keiter, S., Rastall, A., Kosmehl, T., Wurm, K., Erdinger, L., Braunbeck, T., and Hollert, H. (2006) Ecotoxicological assessment of sediment, suspended matter and water samples in the upper Danube River. A pilot study in search for the causes for the decline of fish catches. Environmental science and pollution research international. 13(5):308-319

Kosmehl, T., Hallare, A.V., Reifferscheid, G., Manz, W., Braunbeck, T., and Hollert, H. (2006) A novel contact assay for testing genotoxicity of chemicals and whole sediments in zebrafish embryos. Environmental toxicology and chemistry. 25(8):2097-2106

Diekmann, M., Waldmann, P,, Schnurstein, A., Grummt, T., Braunbeck, T., and Nagel, R. (2004) On the relevance of genotoxicity for fish populations II: genotoxic effects in zebrafish (Danio rerio) exposed to 4-nitroquinoline-1-oxide in a complete life-cycle test. Aquatic toxicology (Amsterdam, Netherlands). 68(1):27-37

Islinger, M., Willimski, D., Volkl, A., and Braunbeck, T. (2003) Effects of 17a-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 62(2):85-103

Strmac, M., Oberemm, A., and Braunbeck, T. (2002) Effects of sediment eluates and extracts from differently polluted small rivers on zebrafish embryos and larvae. Journal of Fish Biology. 61(1):24-38

Schnurstein, A. and Braunbeck, T. (2001) Tail moment versus tail length-application of an in vitro version of the comet assay in biomonitoring for genotoxicity in native surface waters using primary hepatocytes and gill cells from zebrafish (Danio rerio). Ecotoxicology and environmental safety. 49(2):187-196

Strmac, M. and Braunbeck, T. (1999) Effects of triphenyltin acetate on survival, hatching success, and liver ultrastructure of early life stages of zebrafish (Danio rerio). Ecotoxicology and environmental safety. 44(1):25-39

Burkhardt-Holm, P., Oulmi, Y., Schroeder, A., Storch, V., and Braunbeck, T. (1999) Toxicity of 4-chloroaniline in early life stages of zebrafish (Danio rerio): II. Cytopathology and regeneration of liver and gills after prolonged exposure to waterborne 4-chloroaniline. Archives of environmental contamination and toxicology. 37(1):85-102

Braunbeck, T. (1998) Cytological alterations in fish hepatocytes following in vivo and in vitro sublethal exposure to xenobiotics — structural biomarkers of environmental contamination. Fish Ecotoxicology. 86:61-140

Oulmi, Y. and Braunbeck, T. (1996) Toxicity of 4-chloroaniline in early life-stages of zebrafish (Brachydanio rerio): I. cytopathology of liver and kidney after microinjection. Archives of environmental contamination and toxicology. 30(3):390-402

Phromkunthong, W., Storch, V., Braunbeck, T. (1994) Sexual dimorphism in the reaction of zebrafish (Brachydanio rerio) to ascorbic acid deficiency: Induction of steatosis in hepatocytes of male fish. Zeitschrift fur angewandte Ichthyologie = Journal of applied ichthyology. 10(2-3):146-153

Braunbeck, T., Burkhardt-Holm, P., Gorge, G., Nagel, R., Negele, R.D., and Storch, V. (1992) Rainbow trout and zebrafish, two models for continuous toxicity tests: relative sensitivity species and organ specificity in cytopathologic reaction of liver and intestines to atrazine. Schriftenr-Ver-Wasser-Boden-Lufthyg.. 89:109-145

Braunbeck, T., Gorge, G., Storch, V., and Nagel, R. (1990) Hepatic steatosis in zebrafish (Brachydanio rerio) induced by long-term exposure to gamma-hexachlorocyclohexane. Ecotoxicology and environmental safety. 19(3):355-374

Braunbeck, T., Storch, V., and Bresch, H. (1990) Species-specific reaction of liver ultrastructure in zebrafish (Brachydanio rerio) and trout (Salmo gairdneri) after prolonged exposure to 4-chloroaniline. Archives of environmental contamination and toxicology. 19:405-418

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