ZFIN ID: ZDB-PERS-960805-485
Sagerström, Charles
Email: charles.sagerstrom@cuanschutz.edu
URL: https://profiles.ucdenver.edu/display/21098457
Affiliation: Sagerström Lab
Address: Department of Pediatrics Research 1 South; Room 12105 University of Colorado Medical School Mail Stop 8108 12801 E. 17th Avenue Aurora, CO 80045
Country: United States
Phone: (303) 724 9760
Fax:
ORCID ID: 0000-0002-1509-5810


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Kim, Y.I., O'Rourke, R., Sagerström, C.G. (2023) scMultiome analysis identifies embryonic hindbrain progenitors with mixed rhombomere identities. eLIFE. 12:
Bhandari, S., Hong, K., Miyawaki-Kuwakado, A., Tomimatsu, K., Kim, Y.I., Nam, I.K., Sagerstrom, C.G., Nakamura, M., Choe, S.K. (2022) nudt7 gene depletion causes transcriptomic change in early development of zebrafish. Journal of biochemistry. 173(1):53-63
Stanney, W., Ladam, F., Donaldson, I.J., Parsons, T.J., Maehr, R., Bobola, N., Sagerström, C.G. (2019) Combinatorial action of NF-Y and TALE at embryonic enhancers defines distinct gene expression programs during zygotic genome activation in zebrafish. Developmental Biology. 459(2):161-180
Yildiz, O., Downes, G.B., Sagerström, C.G. (2019) Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain. Neural Development. 14:5
Ghosh, P., Maurer, J.M., Sagerström, C.G. (2018) Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish. Neural Development. 13:13
Ladam, F., Stanney, W., Donaldson, I.J., Yildiz, O., Bobola, N., Sagerström, C.G. (2018) TALE factors use two distinct functional modes to control an essential zebrafish gene expression program. eLIFE. 7
Maurer, J.M., Sagerström, C.G. (2018) A parental requirement for dual-specificity phosphatase 6 in zebrafish. BMC Developmental Biology. 18:6
Ghosh, P., Sagerström, C.G. (2018) Developing roles for Hox proteins in hindbrain gene regulatory networks. The International journal of developmental biology. 62:767-774
Zannino, D.A., Sagerström, C.G. (2015) An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system. Neural Development. 10:24
Amin, S., Donaldson, I.J., Zannino, D.A., Hensman, J., Rattray, M., Losa, M., Spitz, F., Ladam, F., Sagerström, C., Bobola, N. (2015) Hoxa2 selectively enhances Meis binding to change a branchial arch ground state. Developmental Cell. 32:265-77
Zannino, D.A., Downes, G.B., Sagerström, C.G. (2014) prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements. Developmental Biology. 390:247-60
Weicksel, S.E., Gupta, A., Zannino, D.A., Wolfe, S.A., Sagerström, C.G. (2014) Targeted germ line disruptions reveal general and species-specific roles for paralog group 1 hox genes in zebrafish. BMC Developmental Biology. 14:25
Choe, S.K., Ladam, F., and Sagerström, C.G. (2014) TALE factors poise promoters for activation by Hox proteins. Developmental Cell. 28(2):203-211
Ladam, F., Sagerström, C.G. (2014) Hox regulation of transcription: more complex(es). Developmental Dynamics : an official publication of the American Association of Anatomists. 243:4-15
Ladam, F., Sagerström, C.G. (2014) Functional analysis of hox genes in zebrafish. Methods in molecular biology (Clifton, N.J.). 1196:133-44
Weicksel, S.E., Xu, J., and Sagerström, C.G. (2013) Dynamic Nucleosome Organization at hox Promoters during Zebrafish Embryogenesis. PLoS One. 8(5):e63175
Choe, S.K., Nakamura, M., Ladam, F., Etheridge, L., and Sagerström, C.G. (2012) A Gal4/UAS system for conditional transgene expression in rhombomere 4 of the zebrafish hindbrain. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(6):1125-1132
Zannino, D.A., Sagerström, C.C., and Appel, B. (2012) Olig2-expressing hindbrain cells are required for migrating facial motor neurons. Developmental Dynamics : an official publication of the American Association of Anatomists. 241(2):315-326
Choe, S.K., Zhang, X., Hirsch, N., Straubhaar, J., and Sagerström, C.G. (2011) A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center. Developmental Biology. 358(2):356-67
Mallappa, C., Nasipak, B.T., Etheridge, L., Androphy, E.J., Jones, S.N., Sagerström, C.G., Ohkawa, Y., and Imbalzano, A.N. (2010) Myogenic microRNA expression requires ATP-dependent chromatin remodeling enzyme function. Molecular and cellular biology. 30(13):3176-3186
Alexa, K., Choe, S.K., Hirsch, N., Etheridge, L., Laver, E., and Sagerström, C.G. (2009) Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish. PLoS One. 4(12):e8261
Choe, S.K., Lu, P., Nakamura, M., Lee, J., and Sagerström, C.G. (2009) Meis cofactors control HDAC and CBP accessibility at Hox-regulated promoters during zebrafish embryogenesis. Developmental Cell. 17(4):561-567
Nakamura, M., Choe, S.K., Runko, A.P., Gardner, P.D., and Sagerström, C.G. (2008) Nlz1/Znf703 acts as a repressor of transcription. BMC Developmental Biology. 8:108
Choe, S.K., Hirsch, N., Zhang, X., and Sagerström, C.G. (2008) hnf1b genes in zebrafish hindbrain development. Zebrafish. 5(3):179-187
diIorio, P., Alexa, K., Choe, S.K., Etheridge, L., and Sagerström, C.G. (2007) TALE-Family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm. Developmental Biology. 304(1):221-231
Choe, S.K., and Sagerström, C.G. (2005) Variable Meis-dependence among paralog group-1 Hox proteins. Biochemical and Biophysical Research Communications. 331(4):1384-1391
Sagerström, C.G., Gammill, L.S., Veale, R., and Sive, H. (2005) Specification of the enveloping layer and lack of autoneuralization in zebrafish embryonic explants. Developmental Dynamics : an official publication of the American Association of Anatomists. 232(1):85-97
Nakamura, M., Runko, A.P., Sagerström, C.G. (2004) A novel subfamily of zinc finger genes involved in embryonic development. Journal of cellular biochemistry. 93:887-95
Choe, S.K., and Sagerström, C.G. (2004) Paralog group 1 hox genes regulate rhombomere 5/6 expression of vhnf1, a repressor of rostral hindbrain fates, in a meis-dependent manner. Developmental Biology. 271(2):350-361
Runko, A.P. and Sagerström, C.G. (2004) Isolation of nlz2 and characterization of essential domains in Nlz-family proteins. The Journal of biological chemistry. 279(12):11917-11925
Roy, N.M., and Sagerström, C.G. (2004) An early Fgf signal required for gene expression in the zebrafish hindbrain primordium. Dev. Brain Res.. 148(1):27-42
Runko, A.P. and Sagerström, C.G. (2003) Nlz belongs to a family of zinc-finger-containing repressors and controls segmental gene expression in the zebrafish hindbrain. Developmental Biology. 262(2):254-267
Lane, M.E., Runko, A.P., Roy, N.M., and Sagerström, C.G. (2002) Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4. Mechanisms of Development. (Suppl.) 119:S185-S189
Lane, M.E., Runko, A.P., Roy, N.M., and Sagerström, C.G. (2002) RETRACTED: Dynamic expression and regulation by Fgf8 and Pou2 of the zebrafish LIM-only gene, lmo4. Gene expression patterns : GEP. 2(3-4):207-211
Etheridge, L., diIorio, P. and Sagerström, C.G. (2002) A zebrafish unc-45 related gene expressed during muscle development. Developmental Dynamics : an official publication of the American Association of Anatomists. 224(4):457-460
Choe, S.K., Vlachakis, N., and Sagerström (2002) Meis proteins are essential for hindbrain development in the zebrafish. Developmental Biology. 247(2):495
Runko, A.P., and Sagerström, C.G. (2002) Roles of the nlz zinc finger protein in zebrafish development. Developmental Biology. 247(2):494-495
Choe, S.K., Vlachakis, N., and Sagerström, C.G. (2002) Meis family proteins are required for hindbrain development in the zebrafish. Development (Cambridge, England). 129(3):585-595
Sagerström, C.G., Kao, B.A., Lane, M.E., and Sive, H. (2001) Isolation and characterization of posteriorly restricted genes in the zebrafish gastrula. Developmental Dynamics : an official publication of the American Association of Anatomists. 220(4):402-408
Vlachakis, N., Choe, S.K., and Sagerström, C.G. (2001) Meis3 synergizes with Pbx4 and Hoxb1b in promoting hindbrain fates in the zebrafish. Development (Cambridge, England). 128(8):1299-1312
Vlachakis, N., Ellstrom, D.R., and Sagerström, C.G. (2000) A novel Pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b. Developmental Dynamics : an official publication of the American Association of Anatomists. 217(1):109-119
Grinblat, Y., Lane, M.E., Sagerström, C., and Sive, H. (1999) Analysis of zebrafish development using explant culture assays. In The Zebrafish: Biology. H.W. Detrich, L.I. Zon, and M. Westerfield, eds. Methods Cell Biol.. 59:127-156
Sagerström, C.G., Grinblat, Y., and Sive, H. (1996) Anteroposterior patterning in the zebrafish, Danio rerio: an explant assay reveals inductive and suppressive cell interactions. Development (Cambridge, England). 122:1873-1883

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