ZFIN Person: Aleström, Peter

ZFIN ID: ZDB-PERS-960805-22

ZFIN ID: ZDB-PERS-960805-22

Aleström, Peter

Email:	peter.alestrom@nmbu.no
URL:	http://zebrafish.no
Affiliation:	Aleström Lab
Address:	Norwegian University of Life Sciences (NMBU) Faculty of Veterinary Medicine and Biosciences Department of Basic Science and Aquatic Medicine P.O. Box 8146 Dep. 0033 Oslo NORWAY
Country:	Norway
Phone:	47-229-64571
Fax:	47-225-97310
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Langa, X., Neuhaus, P., Lains, D., Stewart, T.J., Borel, N., Certal, A.C., Monteiro, J.F., Aleström, P., Diaz, E., Piragyte, I., Bräutigam, L., Vázquez, R., Hlushchuk, R., Gfeller, L., Mestrot, A., Bigalke, M., Varga, Z.M., Mercader, N. (2021) A Systematic Analysis of Metal and Metalloid Concentrations in Eight Zebrafish Recirculating Water Systems. Zebrafish. 18(4):252-264

Martín, L., Kamstra, J.H., Hurem, S., Lindeman, L.C., Brede, D.A., Aanes, H., Babiak, I., Arenal, A., Oughton, D., Salbu, B., Lyche, J.L., Aleström, P. (2021) Altered non-coding RNA expression profile in F₁ progeny 1 year after parental irradiation is linked to adverse effects in zebrafish. Scientific Reports. 11:4142

den Broeder, M.J., Ballangby, J., Kamminga, L.M., Aleström, P., Legler, J., Lindeman, L.C., Kamstra, J.H. (2020) Inhibition of methyltransferase activity of enhancer of zeste 2 leads to enhanced lipid accumulation and altered chromatin status in zebrafish. Epigenetics & chromatin. 13:5

Aleström, P., D'Angelo, L., Midtlyng, P.J., Schorderet, D.F., Schulte-Merker, S., Sohm, F., Warner, S. (2019) Zebrafish: Housing and husbandry recommendations. Laboratory animals. 54(3):213-224

Filipek-Górniok, B., Ledin, J., Aleström, P., Braeutigam, L. (2019) The Nordic Zebrafish and Husbandry Meeting 2018. Zebrafish. 16(3):329-330

Lindeman, L.C., Kamstra, J.H., Ballangby, J., Hurem, S., Martín, L.M., Brede, D.A., Teien, H.C., Oughton, D.H., Salbu, B., Lyche, J.L., Aleström, P. (2019) Gamma radiation induces locus specific changes to histone modification enrichment in zebrafish and Atlantic salmon. PLoS One. 14:e0212123

Kamstra, J.H., Hurem, S., Martin, L.M., Lindeman, L.C., Legler, J., Oughton, D., Salbu, B., Brede, D.A., Lyche, J.L., Aleström, P. (2018) Ionizing radiation induces transgenerational effects of DNA methylation in zebrafish. Scientific Reports. 8:15373

Hurem, S., Gomes, T., Brede, D.A., Mayer, I., Lobert, V.H., Mutoloki, S., Gutzkow, K.B., Teien, H.C., Oughton, D., Aleström, P., Lyche, J.L. (2018) Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects. Ecotoxicology and environmental safety. 154:19-26

Hurem, S., Martín, L.M., Lindeman, L., Brede, D.A., Salbu, B., Lyche, J.L., Aleström, P., Kamstra, J.H. (2017) Parental exposure to gamma radiation causes progressively altered transcriptomes linked to adverse effects in zebrafish offspring. Environmental pollution (Barking, Essex : 1987). 234:855-863

Hurem, S., Gomes, T., Brede, D.A., Lindbo Hansen, E., Mutoloki, S., Fernandez, C., Mothersill, C., Salbu, B., Kassaye, Y.A., Olsen, A.K., Oughton, D., Aleström, P., Lyche, J.L. (2017) Parental gamma irradiation induces reprotoxic effects accompanied by genomic instability in zebrafish (Danio rerio) embryos. Environmental research. 159:564-578

Hurem, S., Martín, L.M., Brede, D.A., Skjerve, E., Nourizadeh-Lillabadi, R., Lind, O.C., Christensen, T., Berg, V., Teien, H.C., Salbu, B., Oughton, D.H., Aleström, P., Lyche, J.L. (2017) Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression. PLoS One. 12:e0179259

Kamstra, J.H., Sales, L.B., Aleström, P., Legler, J. (2017) Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish. Epigenetics & chromatin. 10:20

Lyche, J.L., Grześ, I.M., Karlsson, C., Nourizadeh-Lillabadi, R., Aleström, P., Ropstad, E. (2016) Parental exposure to natural mixtures of persistent organic pollutants (POP) induced changes in transcription of apoptosis-related genes in offspring zebrafish embryos. Journal of toxicology and environmental health. Part A. 79:602-11

Kamstra, J.H., Aleström, P., Kooter, J.M., Legler, J. (2015) Zebrafish as a model to study the role of DNA methylation in environmental toxicology. Environmental science and pollution research international. 22(21):16262-76

Aceto, J., Nourizadeh-Lillabadi, R., Marée, R., Dardenne, N., Jeanray, N., Wehenkel, L., Aleström, P., van Loon, J.J., Muller, M. (2015) Zebrafish Bone and General Physiology Are Differently Affected by Hormones or Changes in Gravity. PLoS One. 10:e0126928

Kamstra, J.H., Løken, M., Aleström, P., Legler, J. (2015) Dynamics of DNA Hydroxymethylation in Zebrafish. Zebrafish. 12(3):230-7

Ostrup, O., Reiner, A.H., Aleström, P., Collas, P. (2014) The specific alteration of histone methylation profiles by DZNep during early zebrafish development. Biochimica et biophysica acta. Gene regulatory mechanisms. 1839(11):1307-15

Aanes, H., Collas, P., and Aleström, P. (2014) Transcriptome dynamics and diversity in the early zebrafish embryo. Briefings in Functional Genomics. 13(2):95-105

Aanes, H., Winata, C., Moen, L.F., Østrup, O., Mathavan, S., Collas, P., Rognes, T., and Aleström, P. (2014) Normalization of RNA-sequencing data from samples with varying mRNA levels. PLoS One. 9(2):e89158

Andersen, I.S., Lindeman, L.C., Reiner, A.H., Ostrup, O., Aanes, H., Aleström, P., and Collas, P. (2013) Epigenetic marking of the zebrafish developmental program. Current topics in developmental biology. 104:85-112

Cantas, L., Sørby, J.R., Aleström, P., and Sørum, H. (2012) Culturable gut microbiota diversity in zebrafish. Zebrafish. 9(1):26-37

Andersen, I.S., Ostrup, O., Lindeman, L.C., Aanes, H., Reiner, A.H., Mathavan, S., Aleström, P., and Collas, P. (2012) Epigenetic complexity during the zebrafish mid-blastula transition. Biochemical and Biophysical Research Communications. 417(4):1139-1144

Lindeman, L.C., Andersen, I.S., Reiner, A.H., Li, N., Aanes, H., Ostrup, O., Winata, C., Mathavan, S., Muller, F., Aleström, P., and Collas, P. (2011) Prepatterning of Developmental Gene Expression by Modified Histones before Zygotic Genome Activation. Developmental Cell. 21(6):993-1004

Aanes, H., Winata, C.L., Lin, C.H., Chen, J.P., Srinivasan, K.G., Lee, S.G., Lim, A.Y., Hajan, H.S., Collas, P., Bourque, G., Gong, Z., Korzh, V., Aleström, P., and Mathavan, S. (2011) Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. Genome research. 21(8):1328-38

Lindeman, L.C., Reiner, A.H., Mathavan, S., Aleström, P., and Collas, P. (2010) Tiling histone h3 lysine 4 and 27 methylation in zebrafish using high-density microarrays. PLoS One. 5(12):e15651

Nourizadeh-Lillabadi, R., Seilø Torgersen, J., Vestrheim, O., König, M., Aleström, P., and Syed, M. (2010) Early embryonic gene expression profiling of zebrafish prion protein (prp2) morphants. PLoS One. 5(10):e13573

Lindeman, L.C., Vogt-Kielland, L.T., Aleström, P., and Collas, P. (2009) Fish'n ChIPs: Chromatin Immunoprecipitation in the Zebrafish Embryo. Methods in molecular biology (Clifton, N.J.). 567:75-86

Holth, T.F., Nourizadeh-Lillabadi, R., Blaesbjerg, M., Grung, M., Holbech, H., Petersen, G.I., Aleström, P., and Hylland, K. (2008) Differential gene expression and biomarkers in zebrafish (Danio rerio) following exposure to produced water components. Aquatic toxicology (Amsterdam, Netherlands). 90(4):277-291

Aleström, P., Begemann, G., Carvan, M.J. 3rd, Cheng, K.C., Crosier, K., Crosier, P., Ekker, S., Huttenlocher, A., Kawakami, K., Kelly, G., Korzh, V., Lieschke, G., Mione, M., Neely, M.N., Neuhauss, S., and Trede, N.S. (2008) Views on four key questions about zebrafish research. Zebrafish. 5(1):9-24

Alestrom, P., Holter, J.L., and Nourizadeh-Lillabadi, R. (2006) Zebrafish in functional genomics and aquatic biomedicine. Trends in Biotechnology. 24(1):15-21

Fan, L., Crodian, J., Liu, X., Aleström, A., Aleström, P., and Collodi, P. (2004) Zebrafish Embryo Cells Remain Pluripotent and Germ-Line Competent for Multiple Passages in Culture. Zebrafish. 1(1):21-26

Fan, L., Aleström, A., Aleström, P., and Collodi, P. (2004) Development of cell cultures with competency for contributing to the zebrafish germ line. Critical reviews in eukaryotic gene expression. 14(1-2):43-52

Fan, L., Aleström, A., Aleström, P., and Collodi, P. (2004) Production of zebrafish germline chimeras from cultured cells. Methods in molecular biology (Clifton, N.J.). 254:289-300

Torgersen, J., Nouizadeh-Lillabadi, R., Husebye, H., and Aleström, P. (2002) In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene. BMC Genomics. 3(1):25

Torgersen, J., Collas, P., and Aleström, P. (2000) Gene-Gun-Mediated Transfer of Reporter Genes to Somatic Zebrafish (Danio rerio) Tissues. Marine biotechnology (New York, N.Y.). 2(3):293-300

Liang, M.-R., Aleström, P., and Collas, P. (2000) Glowing zebrafish: integration, transmission, and expression of a single luciferase transgene promoted by noncovalent DNA-nuclear transport peptide complexes. Molecular reproduction and development. 55(1):8-13

Collas, P., Liang, M.R., Vincent, M., and Aleström, P. (1999) Active transgenes in zebrafish are enriched in acetylated histone H4 and dynamically associate with RNA Pol II and splicing complexes. Journal of Cell Science. 112:1045-1054

Collas, P. and Aleström, P. (1998) Nuclear localization signals enhance germline transmission of a transgene in zebrafish. Transgenic Research. 7(4):303-309

Collas, P. and Aleström, P. (1998) Gene transfer into zebrafish embryo nuclei mediated by nuclear localization signals. In New Developments in Marine Biotechnology. :11-14

Aleström, P, Husebye H., and Collas, P. (1998) Efficiency of gene transfer and promoter specificity assayed by transient gene expression in zebrafish. In Gene Transfer in Aquatic Organisms, de la Fuente & Castro, eds., Springer Verlag. :75-82

Husebye, H., Collas, P., and Aleström, P. (1997) A functional study of the salmon GnRH promoter. Molecular marine biology and biotechnology. 6:357-363

Collas, P. and Aleström, P. (1997) Rapid targeting of plasmid DNA to zebrafish embryo nuclei by the nuclear localization signal of SV40 T antigen. Molecular marine biology and biotechnology. 6(1):48-58

Collas, P. and Aleström, P. (1997) Nuclear localization signals: a driving force for nuclear transport of plasmid DNA in zebrafish. Biochemistry and cell biology = Biochimie et biologie cellulaire. 75:633-640

Collas, P., Husebye, H., and Aleström. P. (1997) Transferring foreign genes into zebrafish eggs by microinjection. In Transgenic Animals - Generation and Use, Part II, Section D, L.M. Houdebine, ed., Harwood Academic Publ.. :119-122

Collas, P. and Aleström, P. (1997) Enhanced germline transmission of transgene with nuclear localizing signals. Molecular and cellular biology. (Suppl.) 8:233a

Collas, P., Husebye, H., and Aleström, P. (1996) The nuclear localization sequence of the SV40 T antigen promotes transgene uptake and expression in zebrafish embryo nuclei. Transgenic Research. 5(6):451-458

Collas, P., Sörensen, A., and Aleström, P. (1996) Fluorescence in situ hybridization analysis of NLS-mediated transgene uptake by zebrafish embryo nuclei. Molecular biology of the cell. (Suppl.) 12:334

Aleström, P., Husebye, H., Kavumpurath, S., and Kisen, G. (1995) Zebrafish, a vertebrate model for transgene expression and biological function. Animal biotechnology. 5:147-154

Kavumpurath, S., Andersen, O., Kisen, K., and Aleström, P. (1993) Gene transfer methods and luciferase gene expression in zebrafish, Brachydanio rerio (HAMILTON). Isr. J. Aquacult.. 45:154-163

Aleström, P., Kisen, G., Klungland, H., and Andersen, O. (1992) Fish gonadotropin-releasing hormone gene and molecular approaches for control of sexual maturation: development of a transgenic fish model. Molecular marine biology and biotechnology. 1:376-379

NON-ZEBRAFISH PUBLICATIONS
Klungland, H., Andersen, O., and Alestr�m, P. 1992. The salmon GnRH encoding gene in salmonids. Molecular Marine Biology and Biotechnology 1, 420-425.

Klungland, H., Andersen, O., Alestr�m, P., and Tora, L. 1993. Estrogen receptor bind to the salmon GnRH gene in a region with long palindromic sequences. Mol Cell Endocrinol, 95, 147-154 .

Kvingedal, A., Alestr�m, P., and R�rvik, K.-A. 1993. The Atlantic salmon (Salmo salar) transferrin cDNA cloning and characterization. Molecular Marine Biology and Biotechnology 2, 233-238.

Bailhache, T., Arazam, A., Klungland, H., Alestr�m, P., Breton, B., and Jego, P. 1994. Localization of salmon GnRH mRNA and peptide in the brain of Atlantic salmon and rainbow trout. Journal of Comparative Neurology, 346, 1-11.

Collas, P. and Alestr�m, P. 1996. The nuclear localization signal of SV40 T antigen directs import of plasmid DNA into Sea urchin male pronuclei in vitro. Mol Reprod Dev 45:431-438.

Husebye, H, Collas, P., and Alestr�m, P. 1997. A functional study of the salmon GnRH promoter . Mol Mar Biol Biotech 6, 357-363.