ZFIN Person: Novoa, Beatriz

ZFIN ID: ZDB-PERS-240215-1

ZFIN ID: ZDB-PERS-240215-1

Novoa, Beatriz

Email:	beatriznovoa@iim.csic.es
URL:
Affiliation:	Immunology and Genomics Lab
Address:	mmunology and Genomics Group Institute of Marine Research. CSIC. Eduardo Cabello 6. 36208 Vigo, Spain
Country:	Spain
Phone:	34 986 21 44 63
Fax:	34 986 29 27 62
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

González-Rodríguez, L., Pérez-Davila, S., Lama, R., López-Álvarez, M., Serra, J., Novoa, B., Figueras, A., González, P. (2023) 3D printing of PLA:CaP:GO scaffolds for bone tissue applications. RSC Advances. 13:159471595915947-15959

Pereiro, P., Rey-Campos, M., Figueras, A., Novoa, B. (2023) An environmentally relevant concentration of antibiotics impairs the immune system of zebrafish (Danio rerio) and increases susceptibility to virus infection. Frontiers in immunology. 13:11000921100092

Pérez-Davila, S., González-Rodríguez, L., Lama, R., López-Álvarez, M., Oliveira, A.L., Serra, J., Novoa, B., Figueras, A., González, P. (2022) 3D-Printed PLA Medical Devices: Physicochemical Changes and Biological Response after Sterilisation Treatments. Polymers. 14(19):

Lama, R., Pereiro, P., Figueras, A., Novoa, B. (2022) Zebrafish as a Vertebrate Model for Studying Nodavirus Infections. Frontiers in immunology. 13:863096

Sendra, M., Pereiro, P., Yeste, M.P., Novoa, B., Figueras, A. (2021) Surgical face masks as a source of emergent pollutants in aquatic systems: Analysis of their degradation product effects in Danio rerio through RNA-Seq. Journal of hazardous materials. 428:128186

Pereiro, P., Lama, R., Figueras, A., Novoa, B. (2021) Characterization of the turbot (Scophthalmus maximus) interleukin-18: Identification of splicing variants, phylogeny, synteny and expression analysis. Developmental and comparative immunology. 124:104199

Bello-Perez, M., Adamek, M., Coll, J., Figueras, A., Novoa, B., Falco, A. (2021) Modulation of the Tissue Expression Pattern of Zebrafish CRP-Like Molecules Suggests a Relevant Antiviral Role in Fish Skin. Biology. 10(2)

Sendra, M., Pereiro, P., Yeste, M.P., Mercado, L., Figueras, A., Novoa, B. (2020) Size matters: Zebrafish (Danio rerio) as a model to study toxicity of nanoplastics from cells to the whole organism. Environmental pollution (Barking, Essex : 1987). 268:115769

Pereiro, P., Figueras, A., Novoa, B. (2020) Zebrafish pten Genes Play Relevant but Distinct Roles in Antiviral Immunity. Vaccines. 8(2):

Pereiro, P., Librán-Pérez, M., Figueras, A., Novoa, B. (2020) Conserved function of zebrafish (Danio rerio) Gdf15 as a sepsis tolerance mediator. Developmental and comparative immunology. 109:103698

Pereiro, P., Álvarez-Rodríguez, M., Valenzuela-Muñoz, V., Gallardo-Escárate, C., Figueras, A., Novoa, B. (2020) RNA-Seq analysis reveals that spring viraemia of carp virus induces a broad spectrum of PIM kinases in zebrafish kidney that promote viral entry. Fish & shellfish immunology. 99:86-98

Bello-Perez, M., Pereiro, P., Coll, J., Novoa, B., Perez, L., Falco, A. (2020) Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol. Scientific Reports. 10:566

Rey-Campos, M., Moreira, R., Romero, A., Medina-Gali, R.M., Novoa, B., Gasset, M., Figueras, A. (2020) Transcriptomic Analysis Reveals the Wound Healing Activity of Mussel Myticin C. Biomolecules. 10(1):

Librán-Pérez, M., Pereiro, P., Figueras, A., Novoa, B. (2019) Antiviral activity of palmitic acid via autophagic flux inhibition in zebrafish (Danio rerio). Fish & shellfish immunology. 95:595-605

Valenzuela-Muñoz, V., Pereiro, P., Álvarez-Rodríguez, M., Gallardo-Escárate, C., Figueras, A., Novoa, B. (2019) Comparative modulation of lncRNAs in wild-type and rag1-heterozygous mutant zebrafish exposed to immune challenge with spring viraemia of carp virus (SVCV). Scientific Reports. 9:14174

Novoa, B., Pereiro, P., López-Muñoz, A., Varela, M., Forn-Cuní, G., Anchelin, M., Dios, S., Romero, A., Martinez-López, A., Medina-Gali, R.M., Collado, M., Coll, J., Estepa, A., Cayuela, M.L., Mulero, V., Figueras, A. (2019) Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress. Aging Cell. 18(5):e13020

Falco, A., Medina-Gali, R.M., Poveda, J.A., Bello-Perez, M., Novoa, B., Encinar, J.A. (2019) Antiviral Activity of a Turbot (Scophthalmus maximus) NK-Lysin Peptide by Inhibition of Low-pH Virus-Induced Membrane Fusion. Marine drugs. 17(2)

Bello-Perez, M., Falco, A., Novoa, B., Perez, L., Coll, J. (2019) Hydroxycholesterol binds and enhances the anti-viral activities of zebrafish monomeric c-reactive protein isoforms. PLoS One. 14:e0201509

Medina-Gali, R.M., Belló-Pérez, M., Ciordia, S., Mena, M.C., Coll, J., Novoa, B., Ortega-Villaizán, M.D.M., Perez, L. (2018) Plasma proteomic analysis of zebrafish following spring viremia of carp virus infection. Fish & shellfish immunology. 86:892-899

Johansen, M.D., Hortle, E., Kasparian, J.A., Romero, A., Novoa, B., Figueras, A., Britton, W.J., de Silva, K., Purdie, A.C., Oehlers, S.H. (2018) Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility. Fish & shellfish immunology. 83:238-242

M, R., Medina-Gali, ., Belló-Pérez, M., Martínez-López, A., Falcó, A., Ortega-Villaizan, M.M., Encinar, J.A., Novoa, B., Coll, J., Perez, L. (2018) Chromatin immunoprecipitation and high throughput sequencing of SVCV-infected zebrafish reveals novel epigenetic histone methylation patterns involved in antiviral immune response. Fish & shellfish immunology. 82:514-521

Álvarez-Rodríguez, M., Pereiro, P., Reyes-López, F.E., Tort, L., Figueras, A., Novoa, B. (2018) Analysis of the Long-Lived Responses Induced by Immunostimulants and Their Effects on a Viral Infection in Zebrafish (Danio rerio).. Frontiers in immunology. 9:1575

M Medina-Gali, R., Ortega-Villaizán, M.D.M., Mercado, L., Novoa, B., Coll, J., Perez, L. (2018) Beta-glucan enhances the response to SVCV infection in zebrafish. Developmental and comparative immunology. 84:307-314

Bello-Perez, M., Falco, A., Medina-Gali, R., Pereiro, P., Encinar, J.A., Novoa, B., Perez, L., Coll, J. (2017) Neutralization of viral infectivity by zebrafish c-reactive protein isoforms. Molecular immunology. 91:145-155

Pereiro, P., Forn-Cuní, G., Dios, S., Coll, J., Figueras, A., Novoa, B. (2017) Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish. Antiviral Research. 145:146-159

García-Valtanen, P., Martínez-López, A., López-Muñoz, A., Bello-Perez, M., Medina-Gali, R.M., Del Mar Ortega-Villaizán, M., Varela, M., Figueras, A., Mulero, V., Novoa, B., Estepa, A., Coll, J. (2017) Corrigendum: Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes. Frontiers in immunology. 8:668

Bello-Perez, M., Falco, A., Medina, R., Encinar, J.A., Novoa, B., Perez, L., Estepa, A., Coll, J. (2017) Structure and functionalities of the human c-reactive protein compared to the zebrafish multigene family of c-reactive-like proteins. Developmental and comparative immunology. 69:33-40

Varela, M., Figueras, A., Novoa, B. (2017) Modelling viral infections using zebrafish: Innate immune response and antiviral research. Antiviral Research. 139:59-68

García-Valtanen, P., Martínez-López, A., López-Muñoz, A., Bello-Perez, M., Medina-Gali, R.M., Ortega-Villaizán, M.D., Varela, M., Figueras, A., Mulero, V., Novoa, B., Estepa, A., Coll, J. (2017) Zebra Fish Lacking Adaptive Immunity Acquire an Antiviral Alert State Characterized by Upregulated Gene Expression of Apoptosis, Multigene Families, and Interferon-Related Genes. Frontiers in immunology. 8:121

Forn-Cuní, G., Varela, M., Pereiro, P., Novoa, B., Figueras, A. (2017) Conserved gene regulation during acute inflammation between zebrafish and mammals. Scientific Reports. 7:41905

Romero, A., Saraceni, P.R., Merino, S., Figueras, A., Tomás, J.M., Novoa, B. (2016) The Animal Model Determines the Results of Aeromonas Virulence Factors.. Frontiers in microbiology. 7:1574

Saraceni, P.R., Romero, A., Figueras, A., Novoa, B. (2016) Establishment of Infection Models in Zebrafish Larvae (Danio rerio) to Study the Pathogenesis of Aeromonas hydrophila. Frontiers in microbiology. 7:1219

Varela, M., Forn-Cuní, G., Dios, S., Figueras, A., Novoa, B. (2016) Proinflammatory Caspase A Activation and an Antiviral State Are Induced by a Zebrafish Perforin after Possible Cellular and Functional Diversification from a Myeloid Ancestor. Journal of Innate Immunity. 8(1):43-56

Kavaliauskis, A., Arnemo, M., Kim, S.H., Ulanova, L., Speth, M., Novoa, B., Dios, S., Evensen, Ø., Griffiths, G.W., Gjøen, T. (2015) Use of Poly(I:C) Stabilized with Chitosan As a Vaccine-Adjuvant Against Viral Hemorrhagic Septicemia Virus Infection in Zebrafish. Zebrafish. 12(6):421-31

Pereiro, P., Varela, M., Diaz-Rosales, P., Romero, A., Dios, S., Figueras, A., Novoa, B. (2015) Zebrafish Nk-lysins: first insights about their cellular and functional diversification. Developmental and comparative immunology. 51(1):148-59

Forn-Cuní, G., Varela, M., Fernández, C.M., Figueras, A., Novoa, B. (2015) Liver immune responses to inflammatory stimuli in a diet-induced obesity model of zebrafish. The Journal of endocrinology. 224(2):159-70

Dios, S., Balseiro, P., Costa, M.M., Romero, A., Boltaña, S., Roher, N., Mackenzie, S., Figueras, A., Novoa, B. (2014) The Involvement of Cholesterol in Sepsis and Tolerance to Lipopolysaccharide Highlighted by the Transcriptome Analysis of Zebrafish (Danio rerio). Zebrafish. 11(5):421-33

Varela, M., Romero, A., Dios, S., van der Vaart, M., Figueras, A., Meijer, A.H., Novoa, B. (2014) Cellular Visualization of Macrophage Pyroptosis and Interleukin-1β Release in a Viral Hemorrhagic Infection in Zebrafish Larvae. Journal of virology. 88(20):12026-40

Varela, M., Diaz-Rosales, P., Pereiro, P., Forn-Cuní, G., Costa, M.M., Dios, S., Romero, A., Figueras, A., Novoa, B. (2014) Interferon-Induced Genes of the Expanded IFIT Family Show Conserved Antiviral Activities in Non-Mammalian Species. PLoS One. 9:e100015

Forn-Cuní, G., Reis, E.S., Dios, S., Posada, D., Lambris, J.D., Figueras, A., Novoa, B. (2014) The Evolution and Appearance of C3 Duplications in Fish Originate an Exclusive Teleost c3 Gene Form with Anti-Inflammatory Activity. PLoS One. 9:e99673

Costa, M.M., Saraceni, P.R., Forn-Cuní, G., Dios, S., Romero, A., Figueras, A., and Novoa, B. (2013) IL-22 is a key player in the regulation of inflammation in fish and involves innate immune cells and PI3K signaling. Developmental and comparative immunology. 41(4):746-755

Ceinos, R.M., Torres-Nuñez, E., Chamorro, R., Novoa, B., Figueras, A., Ruane, N.M., and Rotllant, J. (2013) Critical Role of the Matricellular Protein SPARC in Mediating Erythroid Progenitor Cell Development in Zebrafish. Cells, tissues, organs. 197(3):196-208

Varela, M., Dios, S., Novoa, B., and Figueras, A. (2012) Characterisation, expression and ontogeny of interleukin-6 and its receptors in zebrafish (Danio rerio). Developmental and comparative immunology. 37(1):97-106

Novoa, B., and Figueras, A. (2012) Zebrafish: model for the study of inflammation and the innate immune response to infectious diseases. Advances in experimental medicine and biology. 946:253-275

Dios, S., Romero, A., Chamorro, R., Figueras, A., and Novoa, B. (2010) Effect Of The Temperature During Antiviral Immune Response Ontogeny In Teleosts. Fish & shellfish immunology. 29(6):1019-1027

Encinas, P., Rodriguez-Milla, M.A., Novoa, B., Estepa, A., Figueras, A., and Coll, J. (2010) Zebrafish fin immune responses during high mortality infections with viral haemorrhagic septicemia rhabdovirus. A proteomic and transcriptomic approach. BMC Genomics. 11:518

Novoa, B., Mackenzie, S., and Figueras, A. (2010) Inflammation and Innate Immune Response Against Viral Infections in Marine Fish. Current pharmaceutical design. 16(38):4175-4184

Rodríguez, I., Chamorro, R., Novoa, B., and Figueras, A. (2009) beta-Glucan administration enhances disease resistance and some innate immune responses in zebrafish (Danio rerio). Fish & shellfish immunology. 27(2):369-373

Novoa, B., Bowman, T.V., Zon, L., and Figueras, A. (2009) LPS response and tolerance in the zebrafish (Danio rerio). Fish & shellfish immunology. 26(2):326-331

Rodríguez, I., Novoa, B., and Figueras, A. (2008) Immune response of zebrafish (Danio rerio) against a newly isolated bacterial pathogen Aeromonas hydrophila. Fish & shellfish immunology. 25(3):239-249

Novoa, B., Romero, A., Mulero, V., Rodriguez, I., Fernandez, I., and Figueras, A. (2006) Zebrafish (Danio rerio) as a model for the study of vaccination against viral haemorrhagic septicemia virus (VHSV). Vaccine. 24(31-31):5806-5816

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