ZFIN Person: Payne, Elspeth M. (Beth)

ZFIN ID: ZDB-PERS-230926-1

Payne, Elspeth M. (Beth)

Email:	e.payne@ucl.ac.uk
URL:
Affiliation:	Payne Lab
Address:	UCL Cancer Institute Paul O’Gorman Building 72 Huntley Street London WC1E 6BT
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Lubin, A., Otterstrom, J., Hoade, Y., Bjedov, I., Stead, E., Whelan, M., Gestri, G., Paran, Y., Payne, E. (2021) A versatile, automated and high-throughput drug screening platform for zebrafish embryos. Biology Open. 10(9):

Peña, O.A., Lubin, A., Rowell, J., Hoade, Y., Khokhar, N., Lemmik, H., Mahony, C., Dace, P., Umamahesan, C., Payne, E.M. (2021) Differential Requirement of Gata2a and Gata2b for Primitive and Definitive Myeloid Development in Zebrafish. Frontiers in cell and developmental biology. 9:708113

Peña, O.A., Lubin, A., Hockings, C., Rowell, J., Jung, Y., Hoade, Y., Dace, P.E.I., Valdivia, L.E., Tuschl, K., Boiers, C., Virgilio, M., Richardson, S.E., Payne, E.M. (2021) TLR7 ligation augments hematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling. Blood advances. 5(20):4112-4124

Narla, A., Payne, E.M., Abayasekara, N., Hurst, S.N., Raiser, D.M., Look, A.T., Berliner, N., Ebert, B.L., Khanna-Gupta, A. (2014) L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way. British journal of haematology. 167(4):524-8

Payne, E., Virgilio, M., Narla, A., Sun, H., Levine, M., Paw, B.H., Berliner, N., Look, A.T., Ebert, B., and Khanna-Gupta, A. (2012) L-leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway. Blood. 120(11):2214-2224

Forrester, A.M., Grabher, C., McBride, E.R., Boyd, E.R., Vigerstad, M.H., Edgar, A., Kai, F.B., Da'as, S.I., Payne, E., Look, A.T., and Berman, J.N. (2011) NUP98-HOXA9-transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis. British journal of haematology. 155(2):167-81

Gutierrez, A., Grebliunaite, R., Feng, H., Kozakewich, E., Zhu, S., Guo, F., Payne, E., Mansour, M., Dahlberg, S.E., Neuberg, D.S., Hertog, J.D., Prochownik, E.V., Testa, J.R., Harris, M., Kanki, J.P., and Look, A.T. (2011) Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia. The Journal of experimental medicine. 208(8):1595-603

Payne, E.M., Bolli, N., Rhodes, J., Abdel-Wahab, O.I., Levine, R., Hedvat, C.V., Stone, R., Khanna-Gupta, A., Sun, H., Kanki, J.P., Gazda, H.T., Beggs, A.H., Cotter, F.E., and Look, A.T. (2011) Ddx18 is essential for cell cycle progression in zebrafish hematopoietic cells and is mutated in human acute myeloid leukemia. Blood. 118(4):903-15

Bolli, N., Payne, E.M., Rhodes, J., Gjini, E., Johnston, A.B., Guo, F., Lee, J.S., Stewart, R.A., Kanki, J.P., Chen, A.T., Zhou, Y., Zon, L.I., and Look, A.T. (2011) cpsf1 is required for definitive HSC survival in zebrafish. Blood. 117(15):3996-4007

Grabher, C., Payne, E.M., Johnston, A.B., Bolli, N., Lechman, E., Dick, J.E., Kanki, J.P., and Look, A.T. (2011) Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb. Leukemia. 25(3):506-514

Payne, E. (2011) Ribosomal proteins in zebrafish haematopoiesis and human disease. Ph.D. Thesis.

Bolli, N., Payne, E.M., Grabher, C., Lee, J.S., Johnston, A.B., Falini, B., Kanki, J.P., and Look, A.T. (2010) Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish. Blood. 115(16):3329-3340

Payne, E., and Look, T. (2009) Zebrafish modelling of leukaemias. British journal of haematology. 146(3):247-256

NON-ZEBRAFISH PUBLICATIONS