ZFIN Person: Li, Yun

ZFIN ID: ZDB-PERS-210121-2

ZFIN ID: ZDB-PERS-210121-2

Li, Yun

Email:	aquatics@swu.edu.cn
URL:	http://scxy.swu.edu.cn/s/scxy/zg/20200911/4245398.html
Affiliation:	Yun Li Lab
Address:	Room 104, Teaching Building 30 Laboratory of Fisheries and Aquaculture Biotechnology College of Fisheries Southwest University No.2 Tiansheng Road Beibei, Chongqing 400715
Country:	China
Phone:	+86-023-68251962
Fax:
ORCID ID:	0000-0002-6290-9522

BIOGRAPHY AND RESEARCH INTERESTS

Professor Yun Li got his Ph.D. in Marine Biotechnology from Institute of Oceanology, Chinese Academy of Sciences in 2005, worked his Ph.D. dissertation in Department of Molecular, Cellular and Developmental Biology, University of Michigan at Ann Arbor during 2002-2004. The main research interests of Prof. Li’s Lab are the interactions between fish and biotic and abiotic environmental factors and their molecular mechanism. Using developmental genetics, genomics and CRISPR / cas9 gene editing approaches, we constructed zebrafish homozygous mutants concerning nutrition metabolism and immune stress-related gene knockout aim at elucidating genetic mechanism of fish (including farmed fish) response to stress.

PUBLICATIONS

Xie, L., Tao, Y., Shen, Z., Deng, H., Duan, X., Xue, Y., Chen, D., Li, Y. (2023) Congenital asplenia impairs heme-iron recycling during erythropoiesis in zebrafish. Developmental and comparative immunology. 151:105108

Xu, H., Wang, W., Ouyang, H., Zhang, X., Miao, X., Feng, J., Tao, Y., Li, Y. (2023) Expression profiling and antibacterial analysis of cd36 in mandarin fish, Siniperca chuatsi. Fish & shellfish immunology. 139:108901

Xu, H., Mao, X., Nie, Z., Li, Y. (2023) Oxr1a prevents the premature ovarian failure by regulating oxidative stress and mitochondrial function in zebrafish. Free radical biology & medicine. 203:102-113

Tao, Y., Du, C., Duan, B., Wang, W., Guo, H., Feng, J., Xu, H., Li, Y. (2023) Eugenol exposure inhibits embryonic development and swim bladder formation in zebrafish. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 268:109602

Yang, H., Pu, Y., Liu, C., Gao, L., Duan, X., Liu, S., Chen, D., Zhong, L., Li, Y. (2022) Environmentally relevant concentrations of tris (1,3-dichloro-2-propyl) phosphate induce growth inhibition and oxidative stress in silver carp (Hypophthalmichthys molitrix) larvae. Ecotoxicology and environmental safety. 241:113798

Xu, H., Miao, X.M., Wang, W.B., Wang, G., Li, Y. (2022) Transcriptome analysis reveals the early resistance of zebrafish larvae to oxidative stress. Fish physiology and biochemistry. 48(4):1075-1089

Xu, H., Wang, G., Chi, Y.Y., Kou, Y.X., Li, Y. (2021) Expression profiling and functional characterization of the duplicated Oxr1b gene in zebrafish. Comparative biochemistry and physiology. Part D, Genomics & proteomics. 39:100857

Xu, H., Jiang, Y., Miao, X.M., Tao, Y.X., Xie, L., Li, Y. (2021) A Model Construction of Starvation Induces Hepatic Steatosis and Transcriptome Analysis in Zebrafish Larvae. Biology. 10(2):

Xu, H., Jiang, Y., Li, S., Xie, L., Tao, Y.X., Li, Y. (2020) Zebrafish Oxr1a Knockout Reveals Its Role in Regulating Antioxidant Defenses and Aging. Genes. 11(10):

Xie, L., Tao, Y., Wu, R., Ye, Q., Xu, H., Li, Y. (2019) Congenital asplenia due to a tlx1 mutation reduces resistance to Aeromonas hydrophila infection in zebrafish. Fish & shellfish immunology. 95:538-545

NON-ZEBRAFISH PUBLICATIONS
1.He C, Deng HT, Ba JW, Li S, Chen ZY, Tao YX, Duan XB, Liu SP, Li* Y, Chen DQ*. Food Chain length associated with environmental factors affected by large dam along the Yangtze River. Water, 2020,12,3157. https://www.mdpi.com/2073-4441/12/11/3157/pdf
2.Wu RH, Shen JY, Tian DD, Yu JQ, He T, Yi JH, Li Y*. A potential alternative to traditional antibiotics in aquaculture: yeast glycoprotein exhibits antimicrobial effect in vivo and in vitro on Aeromonas caviae isolated from Carassius auratus gibelio. Veterinary Medicine and Science, 6, 639-648. http://dx.doi.org/10.1002/vms3.253
3.Wu RH, Shen JY, Lai XL, He T, Li Y*. Development of monoclonal antibodies against serum immunoglobulins from gibel carp (Carassius auratus gibelio) and their applications in serodiagnosis of inapparent infection and evaluation of vaccination strategies. Fish and Shellfish Immunology, 2020,96, 69-77. https://doi.org/10.1016/j.fsi.2019.11.059 WOS: 000509617400008.
4.Wu RH, Zhang Q, Li Y *. Development, characterization of monoclonal antibodies specific for the ORF25 membrane protein of Cyprinid herpesvirus 2 and their applications in immunodiagnosis and neutralization of virus infection. Aquaculture, 2020，519, 734904.https://doi.org/10.1016/j.aquaculture.2019.734904.
5.Chen HJ, Wang DQ, Duan XB, Liu SP, Chen DQ*，Li Y*. Hatchery-reared enhancement program for silver carp (Hypophthalmichthys molitrix) in the middle Yangtze River: monitoring the effectiveness based on parentage analysis. Peer J, 2019, e6836. http://doi.org/10.7717/peerj.6836
6.Chen HJ, Wang DQ, Guo J, Duan XB, Liu SP, Chen DQ and Li Y*. Monitoring the genetic effects of broodstock enhancement of silver carp (Hypophthalmichthys molitrix) in middle Yangtze River based on cytb gene and D-loop sequences, Journal of Freshwater Ecology,2019, 34:1, 323-332.DOI:10.1080/02705060.2019.1588795
7.Tao YX, Yang F, Duan BC, He C, Xie L and Li Y*. Complete mitochondrial genome of Odontobutis potamophila (Teleostei, Perciformes, Odontobutidae) from the newly found population of the Upper Yangtze River. Mitochondrial DNA Part B. 2019, 4(1):1362–1363. https://doi.org/10.1080/23802359.2019.1598299
8.Yang F, Tao YX, Duan BC, Zhang Q, Zhai XL and Li Y*. Complete mitochondrial genome of the Yangtze grenadier anchovy, Coilia Brachygnathus (Clupeiformes: Engraulidae) from the upper Yangtze River. Mitochondrial DNA Part B, 2019，4(1):1140-1141. DOI: 10.1080/23802359.2019.1591181
9.Deng HT, Liu MD, Wang JH, Chen DQ, Duan XB, Liu SP Li Y*. Responses of trophic structure variation in fish assemblage to hydrologic regulation in a tributary of the Three Gorges reservoir, China. Applied Ecology and Environmental Research. 2019, 17(2):2085-2104. http://dx.doi.org/10.15666/aeer/1702_20852104
10.Deng HT, Li Y*, Liu MD, Duan XB, Liu SP and Chen DQ. Stable Isotope Analysis Reveals the Importance of Riparian Resources as Carbon Subsidies for Fish Species in the Daning River, a Tributary of Three Gorges Reservoir, China. Water, 2018, 10,1233. doi:10.3390/w10091233