ZFIN Person: Hortle, Elinor

ZFIN ID: ZDB-PERS-180129-1

Hortle, Elinor

Email:	e.hortle@centenary.org.au
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Address:	Centenary Institute, Locked Bag 6, Newtown, NSW 2042
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Kam, J.Y., Hortle, E., Krogman, E., Warner, S.E., Wright, K., Luo, K., Cheng, T., Manuneedhi Cholan, P., Kikuchi, K., Triccas, J.A., Britton, W.J., Johansen, M.D., Kremer, L., Oehlers, S.H. (2022) Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish. Nature communications. 13:952

Tran, W., Kusay, A.S., Hawkins, P.M.E., Cheung, C.Y., Nagalingam, G., Pujari, V., Ford, D.J., Stoye, A., Ochoa, J.L., Audette, R.E., Hortle, E., Oehlers, S.H., Charman, S.A., Linington, R.G., Rubin, E.J., Dowson, C.G., Roper, D.I., Crick, D.C., Balle, T., Cook, G.M., Britton, W.J., Payne, R.J. (2021) Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors. Journal of medicinal chemistry. 64(23):17326-17345

Oehlers, S.H., Hortle, E., Cook, K.M. (2020) A zebrafish model of tuberculosis comorbidity and the effects of HIF-activating intervention. The FEBS journal. 287(18):3917-3920

Hortle, E., Johnson, K.E., Johansen, M.D., Nguyen, T., Shavit, J.A., Britton, W.J., Tobin, D.M., Oehlers, S.H. (2019) Thrombocyte inhibition restores protective immunity to mycobacterial infection in zebrafish. The Journal of infectious diseases. 220(3):524-534

Black, H.D., Xu, W., Hortle, E., Roberston, S.I., Britton, W.J., Kaur, A., New, E.J., Witting, P.K., Chami, B., Oehlers, S.H. (2019) The cyclic nitroxide antioxidant 4-methoxy-TEMPO decreases mycobacterial burden in vivo through host and bacterial targets. Free radical biology & medicine. 135:157-166

Hogan, A.L., Don, E.K., Rayner, S.L., Lee, A., Laird, A.S., Watchon, M., Winnick, C., Tarr, I.S., Morsch, M., Fifita, J.A., Gwee, S.S.L., Formella, I., Hortle, E., Yuan, K.C., Molloy, M.P., Williams, K.L., Nicholson, G.A., Chung, R.S., Blair, I.P., Cole, N.J. (2018) Expression of ALS/FTD-linked mutant CCNF in zebrafish leads to increased cell death in the spinal cord and an aberrant motor phenotype. Human molecular genetics. 28(4):698

Johansen, M.D., Hortle, E., Kasparian, J.A., Romero, A., Novoa, B., Figueras, A., Britton, W.J., de Silva, K., Purdie, A.C., Oehlers, S.H. (2018) Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility. Fish & shellfish immunology. 83:238-242

Johansen, M.D., Kasparian, J.A., Hortle, E., Britton, W.J., Purdie, A.C., Oehlers, S.H. (2018) Mycobacterium marinum infection drives foam cell differentiation in zebrafish infection models. Developmental and comparative immunology. 88:169-172

Spain, M., Wong, J.K., Nagalingam, G., Batten, J.M., Hortle, E., Oehlers, S., Jiang, X.F., Murage, H.E., Orford, J.T., Crisologo, P., Triccas, J.A., Rutledge, P.J., Todd, M.H. (2018) Anti-Tubercular bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and In Vivo Studies. Journal of medicinal chemistry. 61(8):3595-3608

NON-ZEBRAFISH PUBLICATIONS