ZFIN Person: Speleman, Frank

ZFIN ID: ZDB-PERS-151106-6

Speleman, Frank

Email:	Franki.Speleman@UGent.be
URL:
Affiliation:	Center for Medical Genetics Ghent (CMGG) and also: Speleman Lab
Address:	Ghent University Hospital Medical Research Building (MRB) De Pintelaan 185, B-9000 Ghent, Belgium
Country:	Belgium
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Nunes, C., Depestel, L., Mus, L., Keller, K.M., Delhaye, L., Louwagie, A., Rishfi, M., Whale, A., Kara, N., Andrews, S.R., Dela Cruz, F., You, D., Siddiquee, A., Cologna, C.T., De Craemer, S., Dolman, E., Bartenhagen, C., De Vloed, F., Sanders, E., Eggermont, A., Bekaert, S.L., Van Loocke, W., Bek, J.W., Dewyn, G., Loontiens, S., Van Isterdael, G., Decaesteker, B., Tilleman, L., Van Nieuwerburgh, F., Vermeirssen, V., Van Neste, C., Ghesquiere, B., Goossens, S., Eyckerman, S., De Preter, K., Fischer, M., Houseley, J., Molenaar, J., De Wilde, B., Roberts, S.S., Durinck, K., Speleman, F. (2022) RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition. Science advances. 8:eabn1382

Loontiens, S., Dolens, A.C., Strubbe, S., Van de Walle, I., Moore, F.E., Depestel, L., Vanhauwaert, S., Matthijssens, F., Langenau, D.M., Speleman, F., Van Vlierberghe, P., Durinck, K., Taghon, T. (2020) PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation. Frontiers in cell and developmental biology. 8:599472

Garcia, E.G., Veloso, A., Oliveira, M.L., Allen, J.R., Loontiens, S., Brunson, D., Do, D., Yan, C., Morris, R., Iyer, S., Garcia, S.P., Iftimia, N., Van Loocke, W., Matthijssens, F., McCarthy, K., Barata, J.T., Speleman, F., Taghon, T., Gutierrez, A., Van Vlierberghe, P., Haas, W., Blackburn, J.S., Langenau, D.M. (2020) PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis. Leukemia. 35(3):679-690

Loontiens, S., Vanhauwaert, S., Depestel, L., Dewyn, G., Van Loocke, W., Moore, F.E., Garcia, E.G., Batchelor, L., Borga, C., Squiban, B., Malone-Perez, M., Volders, P.J., Olexiouk, V., Van Vlierberghe, P., Langenau, D.M., Frazer, J.K., Durinck, K., Speleman, F. (2020) A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models. Leukemia. 34(12):3398-3403

Loontiens, S., Depestel, L., Vanhauwaert, S., Dewyn, G., Gistelinck, C., Verboom, K., Van Loocke, W., Matthijssens, F., Willaert, A., Vandesompele, J., Speleman, F., Durinck, K. (2019) Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes. BMC Genomics. 20:228

Garcia, E.G., Iyer, S., Garcia, S.P., Loontiens, S., Sadreyev, R.I., Speleman, F., Langenau, D.M. (2018) Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia. Leukemia. 32:1860-1865

Renard, M., Vanhauwaert, S., Vanhomwegen, M., Rihani, A., Vandamme, N., Goossens, S., Berx, G., Van Vlierberghe, P., Haigh, J.J., Decaesteker, B., Van Laere, J., Lambertz, I., Speleman, F., Vandesompele, J., Willaert, A. (2018) Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice. Scientific Reports. 8:7642

Vanhauwaert, S., Lefever, S., Coucke, P., Speleman, F., De Paepe, A., Vandesompele, J., Willaert, A. (2016) RT-qPCR gene expression analysis in zebrafish: Preanalytical precautions and use of expressed repetitive elements for normalization. Methods in cell biology. 135:329-42

NON-ZEBRAFISH PUBLICATIONS