ZFIN Person: Ledin, Johan

ZFIN ID: ZDB-PERS-151015-3

Ledin, Johan

Email:	johan.ledin@ebc.uu.se
URL:
Affiliation:	Uppsala University Zebrafish Facility, Regional SciLifeLab Facility
Address:	Evolutionary Biology Centre, EBC Norbyvägen 18A, 75236 Uppsala Sweden
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ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Habicher, J., Varshney, G.K., Waldmann, L., Snitting, D., Allalou, A., Zhang, H., Ghanem, A., Öhman Mägi, C., Dierker, T., Kjellén, L., Burgess, S.M., Ledin, J. (2022) Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development. PLoS Genetics. 18:e1010067

Filipek-Górniok, B., Habicher, J., Ledin, J., Kjellén, L. (2020) Heparan Sulfate Biosynthesis in Zebrafish. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 69(1):49-60

Banote, R.K., Chebli, J., Şatır, T.M., Varshney, G.K., Camacho, R., Ledin, J., Burgess, S.M., Abramsson, A., Zetterberg, H. (2020) Amyloid precursor protein-b facilitates cell adhesion during early development in zebrafish. Scientific Reports. 10:10127

Morikawa, M., Mitani, Y., Holmborn, K., Kato, T., Koinuma, D., Maruyama, J., Vasilaki, E., Sawada, H., Kobayashi, M., Ozawa, T., Morishita, Y., Bessho, Y., Maeda, S., Ledin, J., Aburatani, H., Kageyama, R., Maruyama, K., Heldin, C.H., Miyazono, K. (2019) The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension. Science signaling. 12(607)

Rothenbücher, T.S.P., Ledin, J., Gibbs, D., Engqvist, H., Persson, C., Billström, G.H. (2019) Zebrafish embryo as a replacement model for initial biocompatibility studies of biomaterials and drug delivery systems. Acta biomaterialia. 100:235-243

Gudmundsson, S., Wilbe, M., Filipek-Górniok, B., Molin, A.M., Ekvall, S., Johansson, J., Allalou, A., Gylje, H., Kalscheuer, V.M., Ledin, J., Annerén, G., Bondeson, M.L. (2019) TAF1, associated with intellectual disability in humans, is essential for embryogenesis and regulates neurodevelopmental processes in zebrafish. Scientific Reports. 9:10730

Filipek-Górniok, B., Ledin, J., Aleström, P., Braeutigam, L. (2019) The Nordic Zebrafish and Husbandry Meeting 2018. Zebrafish. 16(3):329-330

Varshney, G.K., Carrington, B., Pei, W., Bishop, K., Chen, Z., Fan, C., Xu, L., Jones, M., LaFave, M.C., Ledin, J., Sood, R., Burgess, S.M. (2016) A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish. Nature Protocols. 11:2357-2375

Varshney, G.K., Zhang, S., Pei, W., Adomako-Ankomah, A., Fohtung, J., Schaffer, K., Carrington, B., Maskeri, A., Slevin, C., Wolfsberg, T., Ledin, J., Sood, R., Burgess, S.M. (2016) CRISPRz: a database of zebrafish validated sgRNAs. Nucleic acids research. 44(D1):D822-6

Filipek-Górniok, B., Carlsson, P., Haitina, T., Habicher, J., Ledin, J., Kjellén, L. (2015) The Ndst Gene Family in Zebrafish: Role of Ndst1b in Pharyngeal Arch Formation. PLoS One. 10:e0119040

Hayes, A.J., Reynolds, S., Nowell, M.A., Meakin, L.B., Habicher, J., Ledin, J., Bashford, A., Caterson, B., and Hammond, C.L. (2013) Spinal Deformity in Aged Zebrafish Is Accompanied by Degenerative Changes to Their Vertebrae that Resemble Osteoarthritis. PLoS One. 8(9):e75787

Filipek-Górniok, B., Holmborn, K., Haitina, T., Habicher, J., Oliveira, M.B., Hellgren, C., Eriksson, I., Kjellén, L., Kreuger, J., and Ledin, J. (2013) Expression of chondroitin/dermatan sulfate glycosyltransferases during early zebrafish development. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(8):964-75

Holmborn, K., Habicher, J., Kasza, Z., Eriksson, A.S., Filipek-Gorniok, B., Gopal, S., Couchman, J.R., Ahlberg, P., Wiweger, M., Spillman, D., Kreuger, J., and Ledin, J. (2012) On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis. The Journal of biological chemistry. 287(40):33905-33916

NON-ZEBRAFISH PUBLICATIONS