ZFIN ID: ZDB-PERS-140722-4
Durbin, Adam
Email: Adam.durbin@childrens.harvard.edu
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BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Tao, T., Shi, H., Durbin, A.D., Look, A.T. (2021) Targeting ganglioneuromas with mTOR inhibitors. Molecular & cellular oncology. 8:1856621
Tao, T., Shi, H., Wang, M., Perez-Atayde, A.R., London, W.B., Gutierrez, A., Lemos, B., Durbin, A.D., Look, A.T. (2020) Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors. The Journal of experimental medicine. 217(10):
Tao, T., Shi, H., Mariani, L., Abraham, B.J., Durbin, A.D., Zimmerman, M.W., Powers, J.T., Missios, P., Ross, K.N., Perez-Atayde, A.R., Bulyk, M.L., Young, R.A., Daley, G.Q., Look, A.T. (2020) LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors. Proceedings of the National Academy of Sciences of the United States of America. 117(28):16516-16526
Ki, D.H., Oppel, F., Durbin, A.D., Look, A.T. (2019) Mechanisms underlying synergy between DNA topoisomerase I-targeted drugs and mTOR kinase inhibitors in NF1-associated malignant peripheral nerve sheath tumors. Oncogene. 38(39):6585-6598
Zimmerman, M.W., Liu, Y., He, S., Durbin, A.D., Abraham, B.J., Easton, J., Shao, Y., Xu, B., Zhu, S., Zhang, X., Li, Z., Weichert-Leahey, N., Young, R.A., Zhang, J., Look, A.T. (2018) MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification. Cancer discovery. 8:320-335
Ignatius, M.S., Hayes, M.N., Lobbardi, R., Chen, E.Y., McCarthy, K.M., Sreenivas, P., Motala, Z., Durbin, A.D., Molodtsov, A., Reeder, S., Jin, A., Sindiri, S., Beleyea, B.C., Bhere, D., Alexander, M.S., Shah, K., Keller, C., Linardic, C.M., Nielsen, P.G., Malkin, D., Khan, J., Langenau, D.M. (2017) The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma. Cell Reports. 19:2304-2318
Durbin, A.D., Ki, D.H., He, S., Look, A.T. (2016) Malignant Peripheral Nerve Sheath Tumors. Advances in experimental medicine and biology. 916:495-530

NON-ZEBRAFISH PUBLICATIONS