Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
ZFIN ID:
ZDB-PERS-140717-2
Bhatia, Shipra
Email:
shipra.bhatia@igmm.ed.ac.uk
URL:
http://www.hgu.mrc.ac.uk/index.html
Affiliation:
Bhatia Lab
Address:
MRC Human Genetics Unit The MRC Institute of Genetics and Molecular Medicine The University of Edinburgh Western General Hospital Crewe Road Edinburgh EH4 2XU Scotland United Kingdom
Country:
UK
Phone:
+44 (0)131 332 2471
Fax:
+44 (0)131 467 8456
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Uttley, K., Papanastasiou, A.S., Lahne, M., Brisbane, J.M., MacDonald, R.B., Bickmore, W.A., Bhatia, S. (2023) Unique activities of two overlapping
PAX6
retinal enhancers. Life science alliance. 6(11):
Bhatia, S., Kleinjan, D.J., Uttley, K., Mann, A., Dellepiane, N., Bickmore, W.A. (2021) Quantitative spatial and temporal assessment of regulatory element activity in zebrafish. eLIFE. 10:
Bengani, H., Grozeva, D., Moyon, L., Bhatia, S., Louros, S.R., Hope, J., Jackson, A., Prendergast, J.G., Owen, L.J., Naville, M., Rainger, J., Grimes, G., Halachev, M., Murphy, L.C., Spasic-Boskovic, O., van Heyningen, V., Kind, P., Abbott, C.M., Osterweil, E., Raymond, F.L., Roest Crollius, H., FitzPatrick, D.R. (2021) Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability. PLoS One. 16:e0256181
Ravi, V., Bhatia, S., Shingate, P., Tay, B.H., Venkatesh, B., Kleinjan, D.A. (2019) Lampreys, the jawless vertebrates, contain three Pax6 genes with distinct expression in eye, brain and pancreas. Scientific Reports. 9:19559
Mann, A., Bhatia, S. (2019) Zebrafish: A Powerful Model for Understanding the Functional Relevance of Noncoding Region Mutations in Human Genetic Diseases. Biomedicines. 7(3)
Bhatia, S., Gordon, C.T., Foster, R.G., Melin, L., Abadie, V., Baujat, G., Vazquez, M.P., Amiel, J., Lyonnet, S., Heyningen, V.V., Kleinjan, D.A. (2015) Functional Assessment of Disease-Associated Regulatory Variants In Vivo Using a Versatile Dual Colour Transgenesis Strategy in Zebrafish. PLoS Genetics. 11:e1005193
Gordon, C.T., Attanasio, C., Bhatia, S., Benko, S., Ansari, M., Tan, T.Y., Munnich, A., Pennacchio, L.A., Abadie, V., Temple, I.K., Goldenberg, A., van Heyningen, V., Amiel, J., FitzPatrick, D., Kleinjan, D.A., Visel, A., Lyonnet, S. (2014) Identification of novel craniofacial regulatory domains located far upstream of SOX9 and disrupted in Pierre Robin sequence. Human Mutation. 35(8):1011-20
Rainger, J.K., Bhatia, S., Bengani, H., Gautier, P., Rainger, J., Pearson, M., Ansari, M., Crow, J., Mehendale, F., Palinkasova, B., Dixon, M.J., Thompson, P.J., Matarin, M., Sisodiya, S.M., Kleinjan, D.A., and Fitzpatrick, D.R. (2014) Disruption of SATB2 or its long-range cis-regulation by SOX9 causes a syndromic form of Pierre Robin sequence. Human molecular genetics. 23(10):2569-79
Bhatia, S., Monahan, J., Ravi, V., Gautier, P., Murdoch, E., Brenner, S., van Heyningen, V., Venkatesh, B., and Kleinjan, D.A. (2014) A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos. Developmental Biology. 387(2):214-228
Bhatia, S., Bengani, H., Fish, M., Brown, A., Divizia, M.T., de Marco, R., Damante, G., Grainger, R., van Heyningen, V., Kleinjan, D.A. (2013) Disruption of autoregulatory feedback by a mutation in a remote, ultraconserved PAX6 enhancer causes aniridia. American journal of human genetics. 93:1126-34
Coutinho, P., Pavlou, S., Bhatia, S., Chalmers, K.J., Kleinjan, D.A., and Vanheyningen, V. (2011) Discovery and assessment of conserved Pax6 target genes and enhancers. Genome research. 21(8):1349-59
NON-ZEBRAFISH PUBLICATIONS
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.