ZFIN ID: ZDB-PERS-130408-1
Müller, Patrick
Email: pmueller@tuebingen.mpg.de
URL: http://www.eb.tuebingen.mpg.de/research/research-groups/patrick-mueller.html
Affiliation: Müller Lab
Address: Max Planck Institute for Developmental Biology Spemannstraße 35 72076 Tübingen Germany
Country: Germany
Phone: +49 7071 601-364
Fax: +49 7071 601-384

since 2013: Emmy Noether independent research group leader
2007-2013: Postdoctoral fellow and research associate at Harvard University
2004-2007: Ph.D. studies at the MPI for Biophysical Chemistry
1999-2004: Diploma studies in Göttingen, Berkeley, New York

2013-2016: HFSP Career Development Award
2013-2018: Emmy Noether Program Award
2008-2011: HFSP long-term postdoctoral fellowship
2008: Otto Hahn Medal of the Max Planck Society
2007-2008: EMBO long-term postdoctoral fellowship
2003-2006:German National Academic Foundation (Studienstiftung des Deutschen Volkes) undergraduate and graduate fellowships
2002-2003:International Max Planck Research School Scholarship
2001-2002:University of California Education Abroad Program

Rogers, K.W., ElGamacy, M., Jordan, B.M., Müller, P. (2020) Optogenetic investigation of BMP target gene expression diversity. eLIFE. 9:
Soh, G.H., Pomreinke, A.P., Müller, P. (2020) Integration of Nodal and BMP Signaling by Mutual Signaling Effector Antagonism. Cell Reports. 31:107487
Prummel, K.D., Hess, C., Nieuwenhuize, S., Parker, H.J., Rogers, K.W., Kozmikova, I., Racioppi, C., Brombacher, E.C., Czarkwiani, A., Knapp, D., Burger, S., Chiavacci, E., Shah, G., Burger, A., Huisken, J., Yun, M.H., Christiaen, L., Kozmik, Z., Müller, P., Bronner, M., Krumlauf, R., Mosimann, C. (2019) A conserved regulatory program initiates lateral plate mesoderm emergence across chordates. Nature communications. 10:3857
Morishima, T., Krahl, A.C., Nasri, M., Xu, Y., Aghaallaei, N., Findik, B., Klimiankou, M., Ritter, M., Hartmann, M.D., Gloeckner, C.J., Stefańczyk, S., Lindner, C., Oswald, B., Bernhard, R., Hähnel, K., Hermanutz-Klein, U., Ebinger, M., Handgretinger, R., Casadei, N., Welte, K., Andre, M., Müller, P., Bajoghli, B., Skokowa, J. (2019) LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. Blood. 134(14):1159-1175
Mörsdorf, D., Müller, P. (2019) Tuning Protein Diffusivity with Membrane Tethers. Biochemistry. 58:177-181
Piragyte, I., Clapes, T., Polyzou, A., Klein Geltink, R.I., Lefkopoulos, S., Yin, N., Cauchy, P., Curtis, J.D., Klaeylé, L., Langa, X., Beckmann, C.C.A., Wlodarski, M.W., Müller, P., Van Essen, D., Rambold, A., Kapp, F.G., Mione, M., Buescher, J.M., Pearce, E.L., Polyzos, A., Trompouki, E. (2018) A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nature communications. 9:3090
Almuedo-Castillo, M., Bläßle, A., Mörsdorf, D., Marcon, L., Soh, G.H., Rogers, K.W., Schier, A.F., Müller, P. (2018) Scale-invariant patterning by size-dependent inhibition of Nodal signalling. Nature cell biology. 20(9):1032-1042
Rogers, K.W., Müller, P. (2018) Nodal and BMP dispersal during early zebrafish development. Developmental Biology. 447(1):14-23
Soh, G.H., Müller, P. (2018) FRAP Analysis of Extracellular Diffusion in Zebrafish Embryos. Methods in molecular biology (Clifton, N.J.). 1863:107-124
Pomreinke, A.P., Soh, G.H., Rogers, K.W., Bergmann, J.K., Bläßle, A.J., Müller, P. (2017) Dynamics of BMP signaling and distribution during zebrafish dorsal-ventral patterning. eLIFE. 6
Sako, K., Pradhan, S.J., Barone, V., Inglés-Prieto, Á., Müller, P., Ruprecht, V., Čapek, D., Galande, S., Janovjak, H., Heisenberg, C.P. (2016) Optogenetic Control of Nodal Signaling Reveals a Temporal Pattern of Nodal Signaling Regulating Cell Fate Specification during Gastrulation. Cell Reports. 16(3):866-77
Marcon, L., Diego, X., Sharpe, J., Müller, P. (2016) High-throughput mathematical analysis identifies Turing networks for patterning with equally diffusing signals. eLIFE. 5
Rogers, K.W., Bläßle, A., Schier, A.F., Müller, P. (2015) Measuring Protein Stability in Living Zebrafish Embryos Using Fluorescence Decay After Photoconversion (FDAP). Journal of visualized experiments : JoVE. (95):52266

Mueller P, Rogers KW, Shuizi RY, Brand M, Schier AF (2013). Morphogen transport. Development 140 (8), 1621-1638.

Mueller P, Rogers KW, Jordan BM, Lee JS, Robson D, Ramanathan S, Schier AF (2012). Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science, 336(6082), 721-724.

Xu C, Fan ZP, Mueller P, Fogley R, DiBiase A, Trompouki E, Unternaehrer J, Xong F, Torregroza I, Evans T, Megason SG, Daley GQ, Schier AF, Young RA, Zon LI (2012). Nanog Regulates Endoderm Formation through the Mxtx2-Nodal Pathway. Dev Cell, 22(3), 625-638.

Mueller P, Pugazhendhi D, Zeidler MP (2012). Modulation of human JAK/STAT pathway signalling by functionally conserved regulators. JAK-STAT, 1(1), 34-43.

Mueller P, Schier AF (2011). Extracellular movement of signaling molecules. Dev Cell, 21(1), 145-58.

Mueller P, Boutros M, Zeidler MP (2008). Identification of JAK/STAT pathway regulators - Insights from RNAi screens. Semin Cell Dev Biol, 19(4), 360-369.

Ginsberg M, Czeko E, Mueller P, Ren Z, ChenX, Darnell JE Jr. (2007). Amino acid residues required for physical and cooperative interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Mol Cell Biol, 27(18), 6300-6308.

Dietz GP, Valbuena C, Dietz B, Meuer K, Mueller P, Weishaupt JH, Baehr M (2006). Application of a blood-brain-barrier-penetrating form of GDNF in a mouse model for Parkinson’s disease. Brain Res, 1082(1), 61-66.

Mueller P, Kuttenkeuler D, Gesellchen V, Zeidler MP, Boutros M (2005). Identification of JAK/STAT signaling components by genome-wide RNA interference. Nature, 436(7052), 871-875.