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ZFIN ID:
ZDB-PERS-121205-1
Mercader Huber, Nadia
Email:
nadia.mercader@unibe.ch
URL:
https://www.ana.unibe.ch/research/developmental_biology_and_regeneration/index_eng.html
Affiliation:
Mercader Lab
Address:
Country:
Switzerland
Phone:
+ 34 4531200 ext 3105
Fax:
+ 34 4531
ORCID ID:
0000-0002-0905-6399
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Marelli, F., Ernst, A., Mercader, N., Liebling, M. (2023) PAAQ: Paired Alternating AcQuisitions for virtual high frame rate multichannel cardiac fluorescence microscopy. Biological imaging. 3:e20e20
Ernst, A., Piragyte, I., Mp, A.M., Le, N.D., Grandgirard, D., Leib, S.L., Oates, A., Mercader, N. (2023) Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform. Scientific Reports. 13:1703717037
Botos, M.A., Arora, P., Chouvardas, P., Mercader, N. (2023) Transcriptomic data meta-analysis reveals common and injury model specific gene expression changes in the regenerating zebrafish heart. Scientific Reports. 13:54185418
Prummel, K.D., Crowell, H.L., Nieuwenhuize, S., Brombacher, E.C., Daetwyler, S., Soneson, C., Kresoja-Rakic, J., Kocere, A., Ronner, M., Ernst, A., Labbaf, Z., Clouthier, D.E., Firulli, A.B., Sánchez-Iranzo, H., Naganathan, S.R., O'Rourke, R., Raz, E., Mercader, N., Burger, A., Felley-Bosco, E., Huisken, J., Robinson, M.D., Mosimann, C. (2022) Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma. Nature communications. 13:1677
Marques, I.J., Ernst, A., Arora, P., Vianin, A., Hetke, T., Sanz-Morejón, A., Naumann, U., Odriozola, A., Langa, X., Andrés-Delgado, L., Zuber, B., Torroja, C., Osterwalder, M., Simões, F., Englert, C., Mercader, N. (2022) WT1 transcription factor impairs cardiomyocyte specification and drives a phenotypic switch from myocardium to epicardium. Development (Cambridge, England). 149(6):
Marques, I.J., Sanz-Morejón, A., Mercader, N. (2021) Ventricular Cryoinjury as a Model to Study Heart Regeneration in Zebrafish. Methods in molecular biology (Clifton, N.J.). 2158:51-61
Marques, I.J., Sanz-Morejón, A., Mercader, N. (2021) Correction to: Ventricular Cryoinjury as a Model to Study Heart Regeneration in Zebrafish. Methods in molecular biology (Clifton, N.J.). 2158:C1
Peralta, M., Ortiz Lopez, L., Jerabkova, K., Lucchesi, T., Vitre, B., Han, D., Guillemot, L., Dingare, C., Sumara, I., Mercader, N., Lecaudey, V., Delaval, B., Meilhac, S.M., Vermot, J. (2020) Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis. Cell Reports. 32:107932
Sanz-Morejón, A., Mercader, N. (2020) Recent insights into zebrafish cardiac regeneration. Current opinion in genetics & development. 64:37-43
García-Poyatos, C., Cogliati, S., Calvo, E., Hernansanz-Agustín, P., Lagarrigue, S., Magni, R., Botos, M., Langa, X., Amati, F., Vázquez, J., Mercader, N., Enríquez, J.A. (2020) Scaf1 promotes respiratory supercomplexes and metabolic efficiency in zebrafish. EMBO reports. 21(7):e50287
Rodius, S., de Klein, N., Jeanty, C., Sánchez-Iranzo, H., Crespo, I., Ibberson, M., Xenarios, I., Dittmar, G., Mercader, N., Niclou, S.P., Azuaje, F. (2020) Fisetin protects against cardiac cell death through reduction of ROS production and caspases activity. Scientific Reports. 10:2896
Bensimon-Brito, A., Ramkumar, S., Boezio, G.L.M., Guenther, S., Kuenne, C., Helker, C.S.M., Sánchez-Iranzo, H., Iloska, D., Piesker, J., Pullamsetti, S., Mercader, N., Beis, D., Stainier, D.Y.R. (2019) TGF-β Signaling Promotes Tissue Formation during Cardiac Valve Regeneration in Adult Zebrafish. Developmental Cell. 52(1):9-20.e7
Sande-Melón, M., Marques, I.J., Galardi-Castilla, M., Langa, X., Pérez-López, M., Botos, M.A., Sánchez-Iranzo, H., Guzmán-Martínez, G., Ferreira Francisco, D.M., Pavlinic, D., Benes, V., Bruggmann, R., Mercader, N. (2019) Adult sox10
+
Cardiomyocytes Contribute to Myocardial Regeneration in the Zebrafish. Cell Reports. 29:1041-1054.e5
Marques, I.J., Lupi, E., Mercader, N. (2019) Model systems for regeneration: zebrafish. Development (Cambridge, England). 146(18)
Sanz-Morejón, A., García-Redondo, A.B., Reuter, H., Marques, I.J., Bates, T., Galardi-Castilla, M., Große, A., Manig, S., Langa, X., Ernst, A., Piragyte, I., Botos, M.A., González-Rosa, J.M., Ruiz-Ortega, M., Briones, A.M., Salaices, M., Englert, C., Mercader, N. (2019) Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is Required for Organ Regeneration in the Zebrafish. Cell Reports. 28:1296-1306.e6
Andrés-Delgado, L., Ernst, A., Galardi-Castilla, M., Bazaga, D., Peralta, M., Münch, J., González-Rosa, J.M., Marques, I., Tessadori, F., de la Pompa, J.L., Vermot, J., Mercader, N. (2019) Actin dynamics and the Bmp pathway drive apical extrusion of proepicardial cells. Development (Cambridge, England). 146(13):
Conedera, F.M., Pousa, A.M.Q., Mercader, N., Tschopp, M., Enzmann, V. (2019) Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction. Glia. 67(6):1150-1166
Sánchez-Iranzo, H., Galardi-Castilla, M., Sanz-Morejón, A., González-Rosa, J.M., Costa, R., Ernst, A., Sainz de Aja, J., Langa, X., Mercader, N. (2018) Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart. Proceedings of the National Academy of Sciences of the United States of America. 115(16):4188-4193
Sánchez-Iranzo, H., Galardi-Castilla, M., Minguillón, C., Sanz-Morejón, A., González-Rosa, J.M., Felker, A., Ernst, A., Guzmán-Martínez, G., Mosimann, C., Mercader, N. (2018) Tbx5a lineage tracing shows cardiomyocyte plasticity during zebrafish heart regeneration. Nature communications. 9:428
Mercader, N., Serras, F. (2018) Can broken hearts be mended? Ken Poss, a pioneer on heart regeneration research. The International journal of developmental biology. 62:383-386
Awasthi Mishra, N., Drögemüller, C., Jagannathan, V., Keller, I., Wüthrich, D., Bruggmann, R., Beck, J., Schütz, E., Brenig, B., Demmel, S., Moser, S., Signer-Hasler, H., Pieńkowska-Schelling, A., Schelling, C., Sande, M., Rongen, R., Rieder, S., Kelsh, R.N., Mercader, N., Leeb, T. (2017) A structural variant in the 5'-flanking region of the TWIST2 gene affects melanocyte development in belted cattle. PLoS One. 12:e0180170
Vazão, H., Rosa, S., Barata, T., Costa, R., Pitrez, P.R., Honório, I., de Vries, M.R., Papatsenko, D., Benedito, R., Saris, D., Khademhosseini, A., Quax, P.H., Pereira, C.F., Mercader, N., Fernandes, H., Ferreira, L. (2017) High-throughput identification of small molecules that affect human embryonic vascular development. Proceedings of the National Academy of Sciences of the United States of America. 114(15):E3022-E3031
Kappel, S., Marques, I.J., Zoni, E., Stokłosa, P., Peinelt, C., Mercader, N., Kruithof-de Julio, M., Borgström, A. (2017) Store-Operated Ca
2+
Entry as a Prostate Cancer Biomarker - a Riddle with Perspectives.. Current molecular biology reports. 3:208-217
Andrés-Delgado, L., Mercader, N. (2016) Interplay between cardiac function and heart development. Biochimica et biophysica acta. Molecular cell research. 1863(7 Pt B):1707-16
Rodius, S., Androsova, G., Götz, L., Liechti, R., Crespo, I., Merz, S., Nazarov, P.V., de Klein, N., Jeanty, C., González-Rosa, J.M., Muller, A., Bernardin, F., Niclou, S.P., Vallar, L., Mercader, N., Ibberson, M., Xenarios, I., Azuaje, F. (2016) Analysis of the dynamic co-expression network of heart regeneration in the zebrafish. Scientific Reports. 6:26822
Di Donato, V., De Santis, F., Auer, T., Testa, N., Sánchez-Iranzo, H., Mercader, N., Concordet, J.P., Del Bene, F. (2016) 2C-Cas9: a versatile tool for clonal analysis of gene function. Genome research. 26(5):681-92
Bednarek, D., González-Rosa, J.M., Guzmán-Martínez, G., Gutiérrez-Gutiérrez, Ó., Aguado, T., Sánchez-Ferrer, C., Marques, I.J., Galardi-Castilla, M., de Diego, I., Gómez, M.J., Cortés, A., Zapata, A., Jiménez-Borreguero, L.J., Mercader, N., Flores, I. (2015) Telomerase Is Essential for Zebrafish Heart Regeneration. Cell Reports. 12(10):1691-703
González-Rosa, J.M., Guzmán-Martínez, G., Marques, I.J., Sánchez-Iranzo, H., Jiménez-Borreguero, L.J., Mercader, N. (2014) Use of Echocardiography Reveals Reestablishment of Ventricular Pumping Efficiency and Partial Ventricular Wall Motion Recovery upon Ventricular Cryoinjury in the Zebrafish. PLoS One. 9:e115604
Rodius, S., Nazarov, P.V., Nepomuceno-Chamorro, I.A., Jeanty, C., González-Rosa, J.M., Ibberson, M., da Costa, R.M., Xenarios, I., Mercader, N., Azuaje, F. (2014) Transcriptional response to cardiac injury in the zebrafish: systematic identification of genes with highly concordant activity across in vivo models. BMC Genomics. 15:852
Peralta, M., González-Rosa, J.M., Marques, I.J., Mercader, N. (2014) The Epicardium in the Embryonic and Adult Zebrafish. Journal of developmental biology. 2:101-116
Peralta, M., Steed, E., Harlepp, S., González-Rosa, J.M., Monduc, F., Ariza-Cosano, A., Cortés, A., Rayón, T., Gómez-Skarmeta, J.L., Zapata, A., Vermot, J., and Mercader, N. (2013) Heartbeat-Driven Pericardiac Fluid Forces Contribute to Epicardium Morphogenesis. Current biology : CB. 23(18):1726-35
Cavodeassi, F., Bene, F.D., Fürthauer, M., Grabher, C., Herzog, W., Lehtonen, S., Linker, C., Mercader, N., Mikut, R., Norton, W., Strähle, U., Tiso, N., and Foulkes, N.S. (2013) Report of the Second European Zebrafish Principal Investigator Meeting in Karlsruhe, Germany, March 21-24, 2012. Zebrafish. 10(1):119-23
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