Research
Search
Genes / Clones
Expression
Mutants / Tg
Antibodies
Anatomy / GO / Human Disease / Chemical
Publications
Data Mining
Downloads
Data Model
AllianceMine
BioMart
Genomics
BLAST
ZFIN
Ensembl
NCBI
UCSC
Genome Browsers
ZFIN
Ensembl
Vega
GRC
UCSC
NCBI
Resources
Zebrafish Genomics
Other Genome Databases
Resources
General
The Zebrafish Book
Protocol Wiki
Antibody Wiki
Anatomy Atlases
Resources for Students and Educators
Zebrafish Programs
ZF-Health
Husbandry Resources
More...
Resource Centers
Zebrafish International Resource Center (ZIRC)
China Zebrafish Resource Center (CZRC)
European Zebrafish Resource Center (EZRC)
Community
Announcements
News
Meetings
Jobs
Alliance Community Forum
Search
People
Labs
Companies
Societies
International Zebrafish Society (IZFS)
Zebrafish Disease Models Society (ZDMS)
Genetics Society of America (GSA)
Zebrafish Husbandry Association
Support
Nomenclature
Nomenclature Conventions
Line Designations
Wild-Type Lines
Submit a Proposed Gene Name
Submit a Proposed Mutant/Tg Line Name
Publications
Guidelines for Authors
Zebrashare
Citing ZFIN
Using ZFIN
Help & Tips
Glossary
Single Box Search Help
Submit Data
Terms of Use
About Us
About ZFIN
Contact Information
Statistics
Committees
Jobs at ZFIN
Sign In
ZFIN ID:
ZDB-PERS-120530-1
Semina, Elena
Email:
esemina@mcw.edu
URL:
http://www.chw.org/display/PPF/DocID/31793/Nav/0/router.asp
Affiliation:
Semina Lab
Address:
Department of Pediatrics Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee WI 53226 USA
Country:
United States
Phone:
414-955-4996 (office)
Fax:
414-955-6329
ORCID ID:
BIOGRAPHY AND RESEARCH INTERESTS
PUBLICATIONS
Seese, S.E., Muheisen, S., Gath, N., Gross, J.M., Semina, E.V. (2022) Identification of HSPA8 as an interacting partner of MAB21L2 and an important factor in eye development. Developmental Dynamics : an official publication of the American Association of Anatomists. 252(4):510-526
Ferre-Fernández, J.J., Muheisen, S., Thompson, S., Semina, E.V. (2022) CRISPR-Cas9-mediated functional dissection of the foxc1 genomic region in zebrafish identifies critical conserved cis-regulatory elements. Human genomics. 16:49
Seese, S.E., Reis, L.M., Deml, B., Griffith, C., Reich, A., Jamieson, R.V., Semina, E.V. (2021) Identification of missense MAB21L1 variants in microphthalmia and aniridia. Human Mutation. 42(7):877-890
Seese, S.E., Deml, B., Muheisen, S., Sorokina, E., Semina, E.V. (2021) Genetic disruption of zebrafish mab21l1 reveals a conserved role in eye development and affected pathways. Developmental Dynamics : an official publication of the American Association of Anatomists. 250(8):1056-1073
Ferre-Fernández, J.J., Sorokina, E.A., Thompson, S., Collery, R.F., Nordquist, E., Lincoln, J., Semina, E.V. (2020) Disruption of foxc1 genes in zebrafish results in dosage-dependent phenotypes overlapping Axenfeld-Rieger syndrome. Human molecular genetics. 29(16):2723-2735
Reis, L.M., Sorokina, E.A., Thompson, S., Muheisen, S., Velinov, M., Zamora, C., Aylsworth, A.S., Semina, E.V. (2019) De Novo Missense Variants in WDR37 Cause a Severe Multisystemic Syndrome. American journal of human genetics. 105(2):425-433
Hendee, K.E., Sorokina, E.A., Muheisen, S.S., Reis, L.M., Tyler, R.C., Markovic, V., Cuturilo, G., Link, B.A., Semina, E.V. (2018) PITX2 deficiency and associated human disease: insights from the zebrafish model. Human molecular genetics. 27(10):1675-1695
Weh, E., Takeuchi, H., Muheisen, S., Haltiwanger, R.S., Semina, E.V. (2017) Functional characterization of zebrafish orthologs of the human Beta 3-Glucosyltransferase B3GLCT gene mutated in Peters Plus Syndrome. PLoS One. 12:e0184903
Protas, M.E., Weh, E., Footz, T., Kasberger, J., Baraban, S.C., Levin, A.V., Katz, L.J., Ritch, R., Walter, M.A., Semina, E.V., Gould, D.B. (2017) Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma. Human molecular genetics. 26:3630-3638
Greenlees, R., Mihelec, M., Yousoof, S., Speidel, D., Wu, S.K., Rinkwitz, S., Prokudin, I., Perveen, R., Cheng, A., Ma, A., Nash, B., Gillespie, R., Loebel, D.A., Clayton-Smith, J., Lloyd, I.C., Grigg, J.R., Tam, P.P., Yap, A.S., Becker, T.S., Black, G.C., Semina, E., Jamieson, R.V. (2015) Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization. Human molecular genetics. 24(20):5789-804
Deml, B., Reis, L.M., Muheisen, S., Bick, D., Semina, E.V. (2015) EFTUD2 deficiency in vertebrates: Identification of a novel human mutation and generation of a zebrafish model. Birth defects research. Part A, Clinical and molecular teratology. 103(7):630-40
Schilter, K.F., Reis, L.M., Sorokina, E.A., Semina, E.V. (2015) Identification of an Alu-repeat-mediated deletion of OPTN upstream region in a patient with a complex ocular phenotype. Molecular genetics & genomic medicine. 3:490-9
Deml, B., Kariminejad, A., Borujerdi, R.H., Muheisen, S., Reis, L.M., Semina, E.V. (2015) Mutations in MAB21L2 Result in Ocular Coloboma, Microcornea and Cataracts. PLoS Genetics. 11:e1005002
Pathania, M., Semina, E.V., and Duncan, M.K. (2014) Lens extrusion from Laminin alpha 1 mutant zebrafish. TheScientificWorldJournal. 2014:524929
Reis, L.M., Tyler, R.C., Muheisen, S., Raggio, V., Salviati, L., Han, D.P., Costakos, D., Yonath, H., Hall, S., Power, P., and Semina, E.V. (2013) Whole exome sequencing in dominant cataract identifies a new causative factor, CRYBA2, and a variety of novel alleles in known genes. Human genetics. 132(7):761-70
Liu, Y., and Semina, E.V. (2012) pitx2 Deficiency Results in Abnormal Ocular and Craniofacial Development in Zebrafish. PLoS One. 7(1):e30896
Strungaru, M.H., Footz, T., Liu, Y., Berry, F.B., Belleau, P., Semina, E.V., Raymond, V., and Walter, M.A. (2011) PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3. Investigative ophthalmology & visual science. 52(10):7625-33
Volkmann, B.A., Zinkevich, N.S., Mustonen, A., Schilter, K.F., Bosenko, D.V., Reis, L.M., Broeckel, U., Link, B.A., and Semina, E. (2011) Potential novel mechanism for Axenfeld-Rieger syndrome: deletion of a distant region containing regulatory elements of PITX2. Investigative ophthalmology & visual science. 52(3):1450-1459
Sorokina, E.A., Muheisen, S., Mlodik, N., and Semina, E.V. (2011) MIP/Aquaporin 0 Represents a Direct Transcriptional Target of PITX3 in the Developing Lens. PLoS One. 6(6):e21122
NON-ZEBRAFISH PUBLICATIONS
Your Input Welcome
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Name:
Institution:
Email address:
Please leave blank:
Subject:
Comments:
Send your comments
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.