ZFIN Person: Huang, Peng

ZFIN ID: ZDB-PERS-120502-1

Huang, Peng

Email:	huangp@ucalgary.ca
URL:	http://www.penghuanglab.com
Affiliation:	Peng Huang Lab
Address:	Department of Biochemistry and Molecular Biology University of Calgary Health Sciences Centre, Rm 2231 3330 Hospital Drive N.W. Calgary, Alberta, Canada T2N 4N1
Country:	Canada
Phone:	403-220-4612
Fax:
ORCID ID:	0000-0001-7954-8869

BIOGRAPHY AND RESEARCH INTERESTS

I am interested in understanding 1) how cell signaling pathways regulate progenitor cell differentiation and 2) how tissue integrity is maintained.

PUBLICATIONS

Rajan, A.M., Rosin, N.L., Labit, E., Biernaskie, J., Liao, S., Huang, P. (2023) Single-cell analysis reveals distinct fibroblast plasticity during tenocyte regeneration in zebrafish. Science advances. 9:eadi5771eadi5771

Ma, R.C., Kocha, K.M., Méndez-Olivos, E.E., Ruel, T.D., Huang, P. (2023) Origin and diversification of fibroblasts from the sclerotome in zebrafish. Developmental Biology. 498:35-48

Jacobs, C.T., Kejriwal, A., Kocha, K.M., Jin, K.Y., Huang, P. (2022) Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling. Developmental Biology. 489:1-13

Rajan, A.M., Ma, R.C., Kocha, K.M., Zhang, D.J., Huang, P. (2020) Dual function of perivascular fibroblasts in vascular stabilization in zebrafish. PLoS Genetics. 16:e1008800

Jacobs, C.T., Huang, P. (2019) Notch signalling maintains Hedgehog responsiveness via a Gli-dependent mechanism during spinal cord patterning in zebrafish. eLIFE. 8:

Sharma, P., Ruel, T.D., Kocha, K.M., Liao, S., Huang, P. (2019) Single cell dynamics of embryonic muscle progenitor cells in zebrafish. Development (Cambridge, England). 146(14):

Ma, R.C., Jacobs, C.T., Sharma, P., Kocha, K.M., Huang, P. (2018) Stereotypic generation of axial tenocytes from bipartite sclerotome domains in zebrafish. PLoS Genetics. 14:e1007775

Hanwell, D., Hutchinson, S.A., Collymore, C., Bruce, A.E., Louis, R., Ghalami, A., Allison, W.T., Ekker, M., Eames, B.F., Childs, S., Kurrasch, D.M., Gerlai, R., Thiele, T., Scott, I., Ciruna, B., Dowling, J.J., McFarlane, S., Huang, P., Wen, X.Y., Akimenko, M.A., Waskiewicz, A.J., Drapeau, P., Babiuk, L.A., Dragon, D., Smida, A., Buret, A.G., O'Grady, E., Wilson, J., Sowden-Plunkett, L., Tropepe, V. (2016) Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus. Zebrafish. 13 Suppl 1:S153-63

Hudish, L.I., Galati, D.F., Ravanelli, A.M., Pearson, C.G., Huang, P., Appel, B. (2016) miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development (Cambridge, England). 143(13):2292-304

Gagnon, J.A., Valen, E., Thyme, S.B., Huang, P., Ahkmetova, L., Pauli, A., Montague, T.G., Zimmerman, S., Richter, C., Schier, A.F. (2014) Efficient Mutagenesis by Cas9 Protein-Mediated Oligonucleotide Insertion and Large-Scale Assessment of Single-Guide RNAs. PLoS One. 9:e98186

Sittaramane, V., Pan, X., Glasco, D.M., Huang, P., Gurung, S., Bock, A., Li, S., Wang, H., Kawakami, K., Matise, M.P., and Chandrasekhar, A. (2013) The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function. Developmental Biology. 382(2):400-412

Xiong, F., Tentner, A.R., Huang, P., Gelas, A., Mosaliganti, K.R., Souhait, L., Rannou, N., Swinburne, I.A., Obholzer, N.D., Cowgill, P.D., Schier, A.F., and Megason, S.G. (2013) Specified neural progenitors sort to form sharp domains after noisy shh signaling. Cell. 153(3):550-561

Stooke-Vaughan, G.A., Huang, P., Hammond, K.L., Schier, A.F., and Whitfield, T.T. (2012) The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England). 139(10):1777-1787

Huang, P., Xiong, F., Megason, S.G., and Schier, A.F. (2012) Attenuation of notch and hedgehog signaling is required for fate specification in the spinal cord. PLoS Genetics. 8(6):e1002762

Huang, P., and Schier, A.F. (2009) Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England). 136(18):3089-3098

Mao, J., McGlinn, E., Huang, P., Tabin, C.J., and McMahon, A.P. (2009) Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb. Developmental Cell. 16(4):600-606

NON-ZEBRAFISH PUBLICATIONS