ZFIN ID: ZDB-PERS-111118-13
Appelbaum, Lior
Email: lior.appelbaum@biu.ac.il
Affiliation: Appelbaum Lab
Address: The Mina and Everard Goodman Faculty of Life Sciences The Nanotechnology Center, room B-938 Bar Ilan University, Ramat Gan 52900 Israel
Phone: 972-3-7384536


Buchumenski, I., Holler, K., Appelbaum, L., Eisenberg, E., Junker, J.P., Levanon, E.Y. (2021) Systematic identification of A-to-I RNA editing in zebrafish development and adult organs. Nucleic acids research. 49(8):4325-4337
Blitz, E., Matsuda, H., Guenther, S., Morikawa, T., Kubota, Y., Zada, D., Lerer-Goldshtein, T., Stainier, D.Y.R., Appelbaum, L. (2021) Thyroid hormones regulate goblet cell differentiation and Fgf19-Fgfr4 signaling. Endocrinology. 162(5):
Nakajo, H., Chou, M.Y., Kinoshita, M., Appelbaum, L., Shimazaki, H., Tsuboi, T., Okamoto, H. (2020) Hunger Potentiates the Habenular Winner Pathway for Social Conflict by Orexin-Promoted Biased Alternative Splicing of the AMPA Receptor Gene. Cell Reports. 31:107790
Biran, J., Gliksberg, M., Shirat, I., Swaminathan, A., Levitas-Djerbi, T., Appelbaum, L., Levkowitz, G. (2020) Splice-specific deficiency of the PTSD-associated gene PAC1 leads to a paradoxical age-dependent stress behavior. Scientific Reports. 10:9559
Admati, I., Wasserman-Bartov, T., Tovin, A., Rozenblat, R., Blitz, E., Zada, D., Lerer-Goldshtein, T., Appelbaum, L. (2019) Neural alterations and hyperactivity of the hypothalamic-pituitary-thyroid axis in Oatp1c1-deficiency. Thyroid : official journal of the American Thyroid Association. 30(1):161-174
Levitas-Djerbi, T., Sagi, D., Lebenthal-Loinger, I., Lerer-Goldshtein, T., Appelbaum, L. (2019) Neurotensin Enhances Locomotor Activity and Arousal, and Inhibits Melanin-Concentrating Hormone Signalings. Neuroendocrinology. 110(1-2):35-49
Zada, D., Bronshtein, I., Lerer-Goldshtein, T., Garini, Y., Appelbaum, L. (2019) Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons. Nature communications. 10:895
Dvir, H., Elbaz, I., Havlin, S., Appelbaum, L., Ivanov, P.C., Bartsch, R.P. (2018) Neuronal noise as an origin of sleep arousals and its role in sudden infant death syndrome. Science advances. 4:eaar6277
Levitas-Djerbi, T., Appelbaum, L. (2017) Modeling sleep and neuropsychiatric disorders in zebrafish. Current opinion in neurobiology. 44:89-93
Zada, D., Blitz, E., Appelbaum, L. (2017) Zebrafish - An emerging model system to explore thyroid hormone transporters. Molecular and Cellular Endocrinology. 459:53-58
Elbaz, I., Levitas-Djerbi, T., Appelbaum, L. (2017) The Hypocretin/Orexin Neuronal Networks in Zebrafish. Current topics in behavioral neurosciences. 33:75-92
Zada, D., Tovin, A., Lerer-Goldshtein, T., Appelbaum, L. (2016) Pharmacological and BBB-targeted genetic therapies for thyroid hormone-dependent hypomyelination. Disease models & mechanisms. 9(11):1339-1348
Elbaz, I., Zada, D., Tovin, A., Braun, T., Lerer-Goldshtein, T., Wang, G., Mourrain, P., Appelbaum, L. (2016) Sleep-Dependent Structural Synaptic Plasticity of Inhibitory Synapses in the Dendrites of Hypocretin/Orexin Neurons. Molecular neurobiology. 54(8):6581-6597
Shamay-Ramot, A., Khermesh, K., Porath, H.T., Barak, M., Pinto, Y., Wachtel, C., Zilberberg, A., Lerer-Goldshtein, T., Efroni, S., Levanon, E.Y., Appelbaum, L. (2015) Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish. PLoS Genetics. 11:e1005702
Yelin-Bekerman, L., Elbaz, I., Diber, A., Dahary, D., Gibbs-Bar, L., Alon, S., Lerer-Goldshtein, T., Appelbaum, L. (2015) Hypocretin neuron-specific transcriptome profiling identifies the sleep modulator Kcnh4a. eLIFE. 4:e08638
Elbaz, I., Lerer-Goldshtein, T., Okamoto, H., Appelbaum, L. (2015) Reduced synaptic density and deficient locomotor response in neuronal activity-regulated pentraxin 2a mutant zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(4):1220-34
Levitas-Djerbi, T., Yelin-Bekerman, L., Lerer-Goldshtein, T., Appelbaum, L. (2015) The Hypothalamic Leptin-Neurotensin-Hypocretin Neuronal Networks in Zebrafish. The Journal of comparative neurology. 523(5):831-48
Zada, D., Tovin, A., Lerer-Goldshtein, T., Vatine, G.D., Appelbaum, L. (2014) Altered Behavioral Performance and Live Imaging of Circuit-Specific Neural Deficiencies in a Zebrafish Model for Psychomotor Retardation. PLoS Genetics. 10:e1004615
Elbaz, I., Foulkes, N.S., Gothilf, Y., and Appelbaum, L. (2013) Circadian clocks, rhythmic synaptic plasticity and the sleep-wake cycle in zebrafish. Frontiers in neural circuits. 7:9
Vatine, G.D., Zada, D., Lerer-Goldshtein, T., Tovin, A., Malkinson, G., Yaniv, K., and Appelbaum, L. (2013) Zebrafish as a model for monocarboxyl transporter 8-deficiency. The Journal of biological chemistry. 288(1):169-180
Elbaz, I., Yelin-Bekerman, L., Nicenboim, J., Vatine, G., and Appelbaum, L. (2012) Genetic ablation of hypocretin neurons alters behavioral state transitions in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(37):12961-12972
Appelbaum, L., Wang, G., Yokogawa, T., Skariah, G.M., Smith, S.J., Mourrain, P., and Mignot, E. (2010) Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons. Neuron. 68(1):89-98