ZFIN Person: Prajsnar, Thomasz

ZFIN ID: ZDB-PERS-110404-2

Prajsnar, Thomasz

Email:	t.prajsnar@sheffield.ac.uk
URL:
Affiliation:	Renshaw Sheffield Lab
Address:	Renshaw Laboratory, D18 MRC Centre for Developmental and Biomedical Genetics Firth Court Western Bank Sheffield, S10 2TN United Kingdom
Country:	United Kingdom
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Elworthy, S., Rutherford, H.A., Prajsnar, T.K., Hamilton, N.M., Vogt, K., Renshaw, S.A., Condliffe, A.M. (2023) Activated PI3K Delta Syndrome-1 mutations cause neutrophilia in zebrafish larvae. Disease models & mechanisms. 16(3):

Masud, S., van der Burg, L., Storm, L., Prajsnar, T.K., Meijer, A.H. (2019) Rubicon-Dependent Lc3 Recruitment to Salmonella-Containing Phagosomes Is a Host Defense Mechanism Triggered Independently From Major Bacterial Virulence Factors. Frontiers in cellular and infection microbiology. 9:279

Smith, R.E., Salamaga, B., Szkuta, P., Hajdamowicz, N., Prajsnar, T.K., Bulmer, G.S., Fontaine, T., Kołodziejczyk, J., Herry, J.M., Hounslow, A.M., Williamson, M.P., Serror, P., Mesnage, S. (2019) Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system. PLoS pathogens. 15:e1007730

Buchan, K.D., Prajsnar, T.K., Ogryzko, N.V., de Jong, N.W.M., van Gent, M., Kolata, J., Foster, S.J., van Strijp, J.A.G., Renshaw, S.A. (2019) A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase. PLoS One. 14:e0215592

Masud, S., Prajsnar, T.K., Torraca, V., Lamers, G.E.M., Benning, M., Van Der Vaart, M., Meijer, A.H. (2019) Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model. Autophagy. 15(5):796-812

McVicker, G., Prajsnar, T.K., Foster, S.J. (2018) Construction and Use of Staphylococcus aureus Strains to Study Within-Host Infection Dynamics. Methods in molecular biology (Clifton, N.J.). 1736:17-27

Prajsnar, T.K., McVicker, G., Williams, A., Renshaw, S.A., Foster, S.J. (2018) Use of Larval Zebrafish Model to Study Within-Host Infection Dynamics. Methods in molecular biology (Clifton, N.J.). 1736:147-156

Zhang, X., de Maat, V., Guzmán Prieto, A.M., Prajsnar, T.K., Bayjanov, J.R., de Been, M., Rogers, M.R.C., Bonten, M.J.M., Mesnage, S., Willems, R.J.L., van Schaik, W. (2017) RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum. BMC Genomics. 18:893

Salamaga, B., Prajsnar, T.K., Jareño-Martinez, A., Willemse, J., Bewley, M.A., Chau, F., Ben Belkacem, T., Meijer, A.H., Dockrell, D.H., Renshaw, S.A., Mesnage, S. (2017) Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis. PLoS pathogens. 13:e1006526

Widziolek, M., Prajsnar, T.K., Tazzyman, S., Stafford, G.P., Potempa, J., Murdoch, C. (2016) Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases. Scientific Reports. 6:36023

Messad, N., Prajsnar, T.K., Lina, G., O'Callaghan, D., Foster, S.J., Renshaw, S.A., Skaar, E.P., Bes, M., Dunyach-Remy, C., Vandenesch, F., Sotto, A., Lavigne, J.P. (2015) Existence of a Colonizing Staphylococcus aureus Strain Isolated in Diabetic Foot Ulcers. Diabetes. 64:2991-5

Hepburn, L., Prajsnar, T.K., Klapholz, C., Moreno, P., Loynes, C.A., Ogryzko, N.V., Brown, K., Schiebler, M., Hegyi, K., Antrobus, R., Hammond, K.L., Connolly, J., Ochoa, B., Bryant, C., Otto, M., Surewaard, B., Seneviratne, S.L., Grogono, D.M., Cachat, J., Ny, T., Kaser, A., Török, M.E., Peacock, S.J., Holden, M., Blundell, T., Wang, L., Ligoxygakis, P., Minichiello, L., Woods, C.G., Foster, S.J., Renshaw, S.A., Floto, R.A. (2014) Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus. Science (New York, N.Y.). 346:641-6

McVicker, G., Prajsnar, T.K., Williams, A., Wagner, N.L., Boots, M., Renshaw, S.A., Foster, S.J. (2014) Clonal expansion during Staphylococcus aureus infection dynamics reveals the effect of antibiotic intervention. PLoS pathogens. 10:e1003959

Prajsnar, T.K., Renshaw, S.A., Ogryzko, N.V., Foster, S.J., Serror, P., and Mesnage, S. (2013) Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis. Infection and Immunity. 81(11):4271-4279

Prajsnar, T.K., Hamilton, R., Garcia-Lara, J., McVicker, G., Williams, A., Boots, M., Foster, S.J., and Renshaw, S.A. (2012) A privileged intraphagocyte niche is responsible for disseminated infection of Staphylococcus aureus in a zebrafish model. Cellular Microbiology. 14(10):1600-1619

NON-ZEBRAFISH PUBLICATIONS