ZFIN Person: Chu, Jaime

ZFIN ID: ZDB-PERS-101109-2

Chu, Jaime

Email:	jaime.chu@mssm.edu
URL:
Affiliation:	Chu Lab
Address:	Icahn School of Medicine at Mount Sinai 1 Gustave L. Levy Place, Box 1020 New York, New York 10029
Country:	United States
Phone:	212-241-1181
Fax:	212-860-9279
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Magnani, E., Nair, A.R., McBain, I., Delaney, P., Chu, J., Sadler, K.C. (2024) Methods to Study Liver Disease Using Zebrafish Larvae. Methods in molecular biology (Clifton, N.J.). 2707:436943-69

Morrison, J.K., DeRossi, C., Alter, I.L., Nayar, S., Giri, M., Zhang, C., Cho, J.H., Chu, J. (2022) Single-cell transcriptomics reveals conserved cell identities and fibrogenic phenotypes in zebrafish and human liver. Hepatology communications. 6(7):1711-1724

Nayar, S., Morrison, J.K., Giri, M., Gettler, K., Chuang, L.S., Walker, L.A., Ko, H.M., Kenigsberg, E., Kugathasan, S., Merad, M., Chu, J., Cho, J.H. (2021) A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease. Nature. 593(7858):275-281

Chuang, L.S., Morrison, J., Hsu, N.Y., Labrias, P.R., Nayar, S., Chen, E., Villaverde, N., Facey, J.A., Boschetti, G., Giri, M., Castillo-Martin, M., Thin, T.H., Sharma, Y., Chu, J., Cho, J.H. (2019) Zebrafish modeling of intestinal injury, bacterial exposures, and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease. Disease models & mechanisms. 12(8):

DeRossi, C., Bambino, K., Morrison, J., Sakarin, I., Villacorta-Martin, C., Zhang, C., Ellis, J.L., Fiel, M.I., Ybanez, M., Lee, Y.A., Huang, K.L., Yin, C., Sakaguchi, T.F., Friedman, S.L., Villanueva, A., Chu, J. (2019) Mannose Phosphate Isomerase and Mannose Regulate Hepatic Stellate Cell Activation and Fibrosis in Zebrafish and Humans. Hepatology (Baltimore, Md.). 70(6):2107-2122

Bambino, K., Morrison, J., Chu, J. (2019) Hepatotoxicity in Zebrafish Larvae. Methods in molecular biology (Clifton, N.J.). 1965:129-138

Bambino, K., Zhang, C., Austin, C., Amarasiriwardena, C., Arora, M., Chu, J., Sadler, K.C. (2017) Inorganic arsenic causes fatty liver and interacts with ethanol to cause alcoholic liver disease in zebrafish. Disease models & mechanisms. 11(2)

DeRossi, C., Shtraizent, N., Nayar, S., Sachidanandam, R., Katz, L.S., Prince, A., Koh, A.P., Vincek, A., Hadas, Y., Hoshida, Y., Scott, D.K., Eliyahu, E., Freeze, H.H., Sadler, K.C., Chu, J. (2017) MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect. eLIFE. 6

Bambino, K., Chu, J. (2017) Zebrafish in Toxicology and Environmental Health. Current topics in developmental biology. 124:331-367

DeRossi, C., Vacaru, A., Rafiq, R., Cinaroglu, A., Imrie, D., Nayar, S., Baryshnikova, A., Milev, M.P., Stanga, D., Kadakia, D., Gao, N., Chu, J., Freeze, H.H., Lehrman, M.A., Sacher, M., Sadler, K.C. (2016) trappc11 is required for protein glycosylation in zebrafish and humans. Molecular biology of the cell. 27(8):1220-34

Chu, J., Mir, A., Gao, N., Rosa, S., Monson, C., Sharma, V., Steet, R., Freeze, H.H., Lehrman, M.A., and Sadler, K.C. (2013) A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation. Disease models & mechanisms. 6(1):95-105

Chu, J., Loughlin, E.A., Gaur, N.A., Senbanerjee, S., Jacob, V., Monson, C., Kent, B., Oranu, A., Ding, Y., Ukomadu, C., and Sadler, K.C. (2012) UHRF1 phosphorylation by Cyclin A2/CDK2 is required for zebrafish embryogenesis. Molecular biology of the cell. 23(1):59-70

NON-ZEBRAFISH PUBLICATIONS