ZFIN Person: Gut, Philipp

ZFIN ID: ZDB-PERS-100823-6

Gut, Philipp

Email:	Philipp.Gut@rd.nestle.com
URL:
Affiliation:	Chemical Biology Nestlé Institute of Health Sciences
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Phone:	+41 21 632 6303
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Gut, P., Matilainen, S., Meyer, J.G., Pällijeff, P., Richard, J., Carroll, C.J., Euro, L., Jackson, C.B., Isohanni, P., Minassian, B.A., Alkhater, R.A., Østergaard, E., Civiletto, G., Parisi, A., Thevenet, J., Rardin, M.J., He, W., Nishida, Y., Newman, J.C., Liu, X., Christen, S., Moco, S., Locasale, J.W., Schilling, B., Suomalainen, A., Verdin, E. (2020) SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. Nature communications. 11:5927

Weger, M., Weger, B.D., Schink, A., Takamiya, M., Stegmaier, J., Gobet, C., Parisi, A., Kobitski, A.Y., Mertes, J., Krone, N., Strähle, U., Nienhaus, G.U., Mikut, R., Gachon, F., Gut, P., Dickmeis, T. (2020) MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly. eLIFE. 9:

Arribat, Y., Grepper, D., Lagarrigue, S., Richard, J., Gachet, M., Gut, P., Amati, F. (2019) Mitochondria in Embryogenesis: An Organellogenesis Perspective. Frontiers in cell and developmental biology. 7:282

Collodet, C., Foretz, M., Deak, M., Bultot, L., Metairon, S., Viollet, B., Lefebvre, G., Raymond, F., Parisi, A., Civiletto, G., Gut, P., Descombes, P., Sakamoto, K. (2019) AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(11):12374-12391

Dumesic, P.A., Egan, D.F., Gut, P., Tran, M.T., Parisi, A., Chatterjee, N., Jedrychowski, M., Paschini, M., Kazak, L., Wilensky, S.E., Dou, F., Bogoslavski, D., Cartier, J.A., Perrimon, N., Kajimura, S., Parikh, S.M., Spiegelman, B.M. (2019) An Evolutionarily Conserved uORF Regulates PGC1α and Oxidative Metabolism in Mice, Flies, and Bluefin Tuna. Cell Metabolism. 30:190-200.e6

Dickmeis, T., Feng, Y., Mione, M.C., Ninov, N., Santoro, M., Spaink, H.P., Gut, P. (2019) Nano-Sampling and Reporter Tools to Study Metabolic Regulation in Zebrafish. Frontiers in cell and developmental biology. 7:15

Blattmann, P., Stutz, V., Lizzo, G., Richard, J., Gut, P., Aebersold, R. (2019) Generation of a zebrafish SWATH-MS spectral library to quantify 10,000 proteins. Scientific data. 6:190011

Eubelen, M., Bostaille, N., Cabochette, P., Gauquier, A., Tebabi, P., Dumitru, A.C., Koehler, M., Gut, P., Alsteens, D., Stainier, D.Y.R., Garcia-Pino, A., Vanhollebeke, B. (2018) A molecular mechanism for Wnt ligand-specific signaling. Science (New York, N.Y.). 361(6403):

Weger, M., Diotel, N., Weger, B.D., Beil, T., Zaucker, A., Eachus, H.L., Oakes, J.A., do Rego, J.L., Storbeck, K.H., Gut, P., Straehle, U., Rastegar, S., Mueller, F., Krone, N. (2018) Expression and activity profiling of the steroidogenic enzymes of glucocorticoid biosynthesis and the fdx1 co-factors in zebrafish. Journal of neuroendocrinology. 30(4):e12586

Gut, P., Reischauer, S., Stainier, D.Y.R., Arnaout, R. (2017) Little Fish, Big Data: Zebrafish as a Model for Cardiovascular and Metabolic Disease. Physiological reviews. 97:889-938

Gut, P. (2015) Targeting mitochondrial energy metabolism with TSPO ligands. Biochemical Society transactions. 43:537-542

Schlegel, A., Gut, P. (2015) Metabolic insights from zebrafish genetics, physiology, and chemical biology. Cellular and molecular life sciences : CMLS. 72(12):2249-60

Gut, P., Stainier, D.Y. (2015) Whole-Organism Screening for Modulators of Fasting Metabolism Using Transgenic Zebrafish. Methods in molecular biology (Clifton, N.J.). 1263:157-165

Tsuji, N., Ninov, N., Delawary, M., Osman, S., Roh, A.S., Gut, P., Stainier, D.Y. (2014) Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-Cell Proliferation. PLoS One. 9:e104112

Ninov, N., Hesselson, D., Gut, P., Zhou, A., Fidelin, K., and Stainier, D.Y. (2013) Metabolic Regulation of Cellular Plasticity in the Pancreas. Current biology : CB. 23(13):1242-50

Gut, P., Baeza-Raja, B., Andersson, O., Hasenkamp, L., Hsiao, J., Hesselson, D., Akassoglou, K., Verdin, E., Hirschey, M.D., and Stainier, D.Y. (2013) Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nature Chemical Biology. 9(2):97-104

Andersson, O., Adams, B.A., Yoo, D., Ellis, G.C., Gut, P., Anderson, R.M., German, M.S., and Stainier, D.Y. (2012) Adenosine Signaling Promotes Regeneration of Pancreatic beta Cells In Vivo. Cell Metabolism. 15(6):885-894

Jurczyk, A., Roy, N., Bajwa, R., Gut, P., Lipson, K., Yang, C., Covassin, L., Racki, W.J., Rossini, A.A., Phillips, N., Stainier, D.Y., Greiner, D.L., Brehm, M.A., Bortell, R., and diIorio, P. (2011) Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. General and comparative endocrinology. 170(2):334-345

NON-ZEBRAFISH PUBLICATIONS