ZFIN Person: Tamplin, Owen

ZFIN ID: ZDB-PERS-100614-3

Tamplin, Owen

Email:	tamplin@wisc.edu
URL:	https://tamplin.crb.wisc.edu/
Affiliation:	Tamplin Lab
Address:	Department of Cell & Regenerative Biology School of Medicine and Public Health University of Wisconsin-Madison 1111 Highland Ave 4459 WIMR II Madison, WI 53705
Country:	United States
Phone:	1-608-890-0938
Fax:
ORCID ID:	0000-0001-9146-4860

BIOGRAPHY AND RESEARCH INTERESTS

In the Tamplin lab, we study the basic biology of hematopoietic stem cells and their microenvironment.

PUBLICATIONS

Agarwala, S., Kim, K.Y., Phan, S., Ju, S., Kong, Y.E., Castillon, G.A., Bushong, E.A., Ellisman, M.H., Tamplin, O.J. (2022) Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy. eLIFE. 11:

Schiavo, R.K., Tamplin, O.J. (2021) Vascular endothelial growth factor-c regulates hematopoietic stem cell fate in the dorsal aorta. Development (Cambridge, England). 149(2):

Tamplin, O.J. (2020) Making fish a little more human: a zebrafish hematopoietic xenotransplant model is improved by the expression of human cytokines. Haematologica. 105:2346-2347

Li, P., Lahvic, J.L., Binder, V., Pugach, E.K., Riley, E.B., Tamplin, O.J., Panigrahy, D., Bowman, T.V., Barrett, F.G., Heffner, G.C., McKinney-Freeman, S., Schlaeger, T.M., Daley, G.Q., Zeldin, D.C., Zon, L.I. (2019) Author Correction: Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 573:E1

Blaser, B.W., Moore, J.L., Hagedorn, E.J., Li, B., Riquelme, R., Lichtig, A., Yang, S., Zhou, Y., Tamplin, O.J., Binder, V., Zon, L.I. (2017) CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment. The Journal of experimental medicine. 214(4):1011

Anderson, H., Patch, T.C., Reddy, P.N., Hagedorn, E.J., Kim, P.G., Soltis, K.A., Chen, M.J., Tamplin, O.J., Frye, M., MacLean, G.A., Hübner, K., Bauer, D.E., Kanki, J.P., Vogin, G., Huston, N.C., Nguyen, M., Fujiwara, Y., Paw, B.H., Vestweber, D., Zon, L.I., Orkin, S.H., Daley, G.Q., Shah, D.I. (2015) Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression. Blood. 126(26):2811-20

Li, P., Lahvic, J.L., Binder, V., Pugach, E.K., Riley, E.B., Tamplin, O.J., Panigrahy, D., Bowman, T.V., Barrett, F.G., Heffner, G.C., McKinney-Freeman, S., Schlaeger, T.M., Daley, G.Q., Zeldin, D.C., Zon, L.I. (2015) Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. Nature. 523:468-71

Jing, L., Tamplin, O.J., Chen, M.J., Deng, Q., Patterson, S., Kim, P.G., Durand, E.M., McNeil, A., Green, J.M., Matsuura, S., Ablain, J., Brandt, M.K., Schlaeger, T.M., Huttenlocher, A., Daley, G.Q., Ravid, K., Zon, L.I. (2015) Adenosine signaling promotes hematopoietic stem and progenitor cell emergence. The Journal of experimental medicine. 212(5):649-63

Tamplin, O.J., Durand, E.M., Carr, L.A., Childs, S.J., Hagedorn, E.J., Li, P., Yzaguirre, A.D., Speck, N.A., Zon, L.I. (2015) Hematopoietic Stem Cell Arrival Triggers Dynamic Remodeling of the Perivascular Niche. Cell. 160:241-252

Cooney, J.D., Hildick-Smith, G.J., Shafizadeh, E., McBride, P.F., Carroll, K.J., Anderson, H., Shaw, G.C., Tamplin, O.J., Branco, D.S., Dalton, A.J., Shah, D.I., Wong, C., Gallagher, P.G., Zon, L.I., North, T.E., and Paw, B.H. (2013) Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis. Developmental Biology. 373(2):431-441

Tamplin, O.J., White, R.M., Jing, L., Kaufman, C.K., Lacadie, S.A., Li, P., Taylor, A.M., and Zon, L.I. (2012) Small molecule screening in zebrafish: swimming in potential drug therapies. Wiley Interdisciplinary Reviews: Developmental Biology. 1(3):459-468

Tamplin, O.J., Cox, B.J., and Rossant, J. (2011) Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Developmental Biology. 360(2):415-25

Mosimann, C., Kaufman, C.K., Li, P., Pugach, E.K., Tamplin, O.J., and Zon, L.I. (2011) Ubiquitous transgene expression and Cre-based recombination driven by the ubiquitin promoter in zebrafish. Development (Cambridge, England). 138(1):169-177

Tamplin, O.J., and Zon, L.I. (2010) Blood flow: metalloproteases cut loose in primitive erythrocytes. Current biology : CB. 20(13):R561-R562

NON-ZEBRAFISH PUBLICATIONS