ZFIN Person: Melville, David

ZFIN ID: ZDB-PERS-090408-1

Melville, David

Email:	david.melville@vanderbilt.edu
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Affiliation:
Address:	Division of Genetic Medicine Department of Cell and Developmental Biology Developmental Biology Program Vanderbilt University 1165 Light Hall 2215 Garland Av. Nashville, TN 37232-0275 USA
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Unlu, G., Qi, X., Gamazon, E.R., Melville, D.B., Patel, N., Rushing, A.R., Hashem, M., Al-Faifi, A., Chen, R., Li, B., Cox, N.J., Alkuraya, F.S., Knapik, E.W. (2020) Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies. Nature medicine. 26:98-109

Levic, D.S., Minkel, J., Wang, W., Rybski, W.M., Melville, D.B., Knapik, E.W. (2015) Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease. Journal of molecular medicine (Berlin, Germany). 93(2):165-176

Niu, X., Hong, J., Zheng, X., Melville, D.B., Knapik, E.W., Meng, A., Peng, J. (2014) The Nuclear Pore Complex Function of Sec13 Protein Is Required for Cell Survival during Retinal Development. The Journal of biological chemistry. 289:11971-85

Venkateswaran, A., Sekhar, K.R., Levic, D.S., Melville, D.B., Clark, T.A., Rybski, W.M., Walsh, A.J., Skala, M.C., Crooks, P.A., Knapik, E.W., and Freeman, M.L. (2014) The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development. Cancer research. 74(1):38-43

Müller, I.I., Melville, D.B., Tanwar, V., Rybski, W.M., Mukherjee, A., Shoemaker, B.M., Wang, W.D., Schoenhard, J.A., Roden, D.M., Darbar, D., Knapik, E.W., and Hatzopoulos, A.K. (2013) Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Disease models & mechanisms. 6(2):332-341

Wang, W.D., Melville, D.B., Montero-Balaguer, M., Hatzopoulos, A.K., and Knapik, E.W. (2011) Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population. Developmental Biology. 360(1):173-85

Melville, D.B., Montero-Balaguer, M., Levic, D.S., Bradley, K., Smith, J.R., Hatzopoulos, A.K., and Knapik, E.W. (2011) The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis. Disease models & mechanisms. 4(6):763-76

Bradley, K.M., Breyer, J.P., Melville, D.B., Broman, K.W., Knapik, E.W., and Smith, J.R. (2011) An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci. G3 (Bethesda). 1(1):3-9

Liu, D., Wang, W.D., Melville, D.B., Cha, Y.I., Yin, Z., Issaeva, N., Knapik, E.W., and Yarbrough, W.G. (2011) Tumor suppressor Lzap regulates cell cycle progression, doming, and zebrafish epiboly. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(6):1613-1625

Melville, D.B., and Knapik, E.W. (2011) Traffic jams in fish bones: ER-to-Golgi protein transport during zebrafish development. Cell adhesion & migration. 5(2):114-118

Sarmah, S., Barrallo-Gimeno, A., Melville, D.B., Topczewski, J., Solnica-Krezel, L., and Knapik, E.W. (2010) Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis. PLoS One. 5(4):e10367

NON-ZEBRAFISH PUBLICATIONS