ZFIN Person: Otte, Jens

ZFIN ID: ZDB-PERS-090402-1

Otte, Jens

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Address:	Institute of Toxicology and Genetics Forschungszentrum Karlsruhe Postfach 3640 Karlsruhe, D-76021 Germany
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BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Takamiya, M., Stegmaier, J., Kobitski, A.Y., Schott, B., Weger, B.D., Margariti, D., Cereceda Delgado, A.R., Gourain, V., Scherr, T., Yang, L., Sorge, S., Otte, J.C., Hartmann, V., van Wezel, J., Stotzka, R., Reinhard, T., Schlunck, G., Dickmeis, T., Rastegar, S., Mikut, R., Nienhaus, G.U., Strähle, U. (2020) Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves. PLoS Genetics. 16:e1008774

Schott, B., Traub, M., Schlagenhauf, C., Takamiya, M., Antritter, T., Bartschat, A., Löffler, K., Blessing, D., Otte, J.C., Kobitski, A.Y., Nienhaus, G.U., Strähle, U., Mikut, R., Stegmaier, J. (2018) EmbryoMiner: A new framework for interactive knowledge discovery in large-scale cell tracking data of developing embryos. PLoS Computational Biology. 14:e1006128

Otte, J.C., Schultz, B., Fruth, D., Fabian, E., van Ravenzwaay, B., Hidding, B., Salinas, E.R. (2017) Intrinsic Xenobiotic Metabolizing Enzyme Activities in Early Life Stages of Zebrafish (Danio rerio). Toxicological sciences : an official journal of the Society of Toxicology. 159:86-93

Hausen, J., Otte, J.C., Legradi, J., Yang, L., Strähle, U., Fenske, M., Hecker, M., Tang, S., Hammers-Wirtz, M., Hollert, H., Keiter, S.H., Ottermanns, R. (2017) Fishing for contaminants: identification of three mechanism specific transcriptome signatures using Danio rerio embryos. Environmental science and pollution research international. 25(5):4023-4036

Hausen, J., Otte, J.C., Strähle, U., Hammers-Wirtz, M., Hollert, H., Keiter, S.H., Ottermanns, R. (2015) Fold-change threshold screening: a robust algorithm to unmask hidden gene expression patterns in noisy aggregated transcriptome data. Environmental science and pollution research international. 22(21):16384-92

Braunbeck, T., Kais, B., Lammer, E., Otte, J., Schneider, K., Stengel, D., Strecker, R. (2015) The fish embryo test (FET): origin, applications, and future. Environmental science and pollution research international. 22(21):16247-61

Kobitski, A.Y., Otte, J.C., Takamiya, M., Schäfer, B., Mertes, J., Stegmaier, J., Rastegar, S., Rindone, F., Hartmann, V., Stotzka, R., García, A., van Wezel, J., Mikut, R., Strähle, U., Nienhaus, G.U. (2015) An ensemble-averaged, cell density-based digital model of zebrafish embryo development derived from light-sheet microscopy data with single-cell resolution. Scientific Reports. 5:8601

Bluhm, K., Otte, J.C., Yang, L., Zinsmeister, C., Legradi, J., Keiter, S., Kosmehl, T., Braunbeck, T., Strähle, U., Hollert, H. (2014) Impacts of Different Exposure Scenarios on Transcript Abundances in Danio rerio Embryos when Investigating the Toxicological Burden of Riverine Sediments. PLoS One. 9:e106523

Stegmaier, J., Otte, J.C., Kobitski, A., Bartschat, A., Garcia, A., Nienhaus, G.U., Strähle, U., Mikut, R. (2014) Fast segmentation of stained nuclei in terabyte-scale, time resolved 3D microscopy image stacks. PLoS One. 9:e90036

Kosmehl, T., Otte, J.C., Yang, L., Legradi, J., Bluhm, K., Zinsmeister, C., Keiter, S.H., Reifferscheid, G., Manz, W., Braunbeck, T., Strähle, U., and Hollert, H. (2012) A combined DNA-microarray and mechanism-specific toxicity approach with zebrafish embryos to investigate the pollution of river sediments. Reproductive toxicology (Elmsford, N.Y.). 33(2):245-253

Otte, J.C., Schmidt, A.D., Hollert, H., and Braunbeck, T. (2010) Spatio-temporal development of CYP1 activity in early life-stages of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 100(1):38-50

NON-ZEBRAFISH PUBLICATIONS