ZFIN Person: Rajpurohit, Surendra

ZFIN ID: ZDB-PERS-080519-2

ZFIN ID: ZDB-PERS-080519-2

Rajpurohit, Surendra

Email:	srajpurohit@gru.edu
URL:	http://www.augusta.edu/faculty/directory/view.php?id=SRAJPUROHIT
Affiliation:	Rajpurohit Lab
Address:	Georgia Cancer Center, Medical College of Georgia at Augusta University 1410 Laney Walker Blvd I CN 3116A I Augusta, Georgia 30912
Country:	United States
Phone:
Fax:
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

Development of Zebrafish Microglia for health and disease. /SoubleEGFR Research. Role of HER3 isoform and extracellular domain of HER (sHER3)in Melanoma, Ovary and Breast Cancer Research. Role of soluble isoforms (extra cellular domains) of EGFR Family members in targeted therapeutics and establishment of sEGFR as Biomarker in Cancer Research. In-vivo automated HTS Drug Discovery by using Zebrafish model in Diabetes beta cell neogenesis and proliferation, Creation of acute hypoxia in zebrafish model and its impact on Cardiovascular Biology.

PUBLICATIONS

Rajpurohit, S.K., Ouellette, L., Sura, S., Appiah, C., O'Keefe, A., McCarthy, K., Kandepu, U., Ye Mon, M., Kimmerling, K., Arora, V., Lokeshwar, B.L. (2023) Development of a Transparent Transgenic Zebrafish Cellular Phenotype Tg(6xNF-kB:EGFP); Casper(roy^-/-, nacre^-/-) to Study NF-kB Activity. Biomedicines. 11(7):

White, D.T., Eroglu, A.U., Wang, G., Zhang, L., Sengupta, S., Ding, D., Rajpurohit, S.K., Walker, S.L., Ji, H., Qian, J., Mumm, J.S. (2016) ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates. Nature Protocols. 11:2432-2453

Wang, G., Rajpurohit, S.K., Delaspre, F., Walker, S.L., White, D.T., Ceasrine, A., Kuruvilla, R., Li, R.J., Shim, J.S., Liu, J.O., Parsons, M.J., Mumm, J.S. (2015) First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass. eLIFE. 4

Urban, B.E., Neogi, P., Senthilkumar, K., Rajpurohit, S.K., Jagadeeshwaran, P. Seongcheol, K., Fujita, Y., and Neogi, A. (2012) Bioimaging Using the Optimized Nonlinear Optical Properties of ZnO Nanoparticles. IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society. 18(4):1451 - 1456

Jagadeeswaran, P., Carrillo, M., Radhakrishnan, U.P., Rajpurohit, S.K., and Kim, S. (2011) Laser-induced thrombosis in zebrafish. Methods in cell biology. 101:197-203

Carrillo, M., Kim, S., Rajpurohit, S.K., Kulkarni, V., and Jagadeeswaran, P. (2010) Zebrafish von Willebrand factor. Blood cells, molecules & diseases. 45(4):326-333

Kim, S., Radhakrishnan, U.P., Rajpurohit, S.K., Kulkarni, V., and Jagadeeswaran, P. (2010) Vivo-Morpholino knockdown of alphaIIb: A novel approach to inhibit thrombocyte function in adult zebrafish. Blood cells, molecules & diseases. 44(3):169-174

Kim, S., Carlson, R., Zafreen, L., Rajpurohit, S.K., and Jagadeeswaran, P. (2009) Modular, Easy-To-Assemble, Low-Cost Zebrafish Facility. Zebrafish. 6(3):269-274

NON-ZEBRAFISH PUBLICATIONS
C Cai, M Zhu, SK Rajpurohit, NJ Maihle. The effect of p85-sHER3 on cancer cell growth and Migration in Melanoma derived cells. Molecular Biology of the Cell 27 (25 3947), P1941

P Jagadeeswaran, UP Radhakrishnan, S Kim, S K Rajpurohit, D Xie, J-T Hsieh (2011). Mammalian Prostate stem cells to the area of the prostate gland in zebrafish. brafishttp:// cancerres.aacrjournals.org/ content /71/8_Supplement/4377