Our group is studying the molecular mechanisms that control asymmetric versus symmetric development, using the chick and the zebrafish embryos as model organisms. During embryonic development it is important to create left-right asymmetry in the lateral plate mesoderm to allow the correct positioning of the internal organs. In addition, it is fundamental to maintain symmetry between the left and the right sides of the presomitic mesoderm to ensure the perfect allocation of symmetric body structures such as the axial skeleton, skeletal muscles and peripheral nerves.