ZFIN Person: Klemke, Richard

ZFIN ID: ZDB-PERS-070208-2

Klemke, Richard

Email:	rklemke@ucsd.edu
URL:
Affiliation:
Address:	University of California San Diego Department of Pathology and Moores Cancer Center Basic Science Building, Room 1040 9500 Gilman Drive, MC 0612 La Jolla, CA 92093 USA
Country:
Phone:	858-822-5610
Fax:	858-822-4566
ORCID ID:

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

Sahu, D., Huan, J., Wang, H., Sahoo, D., Casteel, D.E., Klemke, R.L., Boss, G.R., Hansel, D.E. (2021) Bladder Cancer Invasion is Mediated by mTORC2-Driven Regulation of Nitric Oxide and Invadopodia Formation. The American journal of pathology. 191(12):2203-2218

Melo, C.M., Wang, H., Fujimura, K., Strnadel, J., Meneghetti, M.C.Z., Nader, H.B., Klemke, R.L., Pinhal, M.A.S. (2021) The Heparan Sulfate Binding Peptide in Tumor Progression of Triple-Negative Breast Cancer. Frontiers in oncology. 11:697626

Strnadel, J., Wang, H., Carromeu, C., Miyanohara, A., Fujimura, K., Blahovcova, E., Nosal, V., Skovierova, H., Klemke, R., Halasova, E. (2018) Transplantation of Human-Induced Pluripotent Stem Cell-Derived Neural Precursors into Early-Stage Zebrafish Embryos. Journal of molecular neuroscience : MN. 65(3):351-358

Wang, H., Lapek, J., Fujimura, K., Strnadel, J., Liu, B., Gonzalez, D.J., Zhang, W., Watson, F., Yu, V., Liu, C., Melo, C.M., Miller, Y.I., Elliott, K.C., Cheresh, D.A., Klemke, R.L. (2018) Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription. Cell discovery. 4:26

Liu, C., Han, T., Stachura, D.L., Wang, H., Vaisman, B.L., Kim, J., Klemke, R.L., Remaley, A.T., Rana, T.M., Traver, D., Miller, Y.I. (2018) Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply. Nature communications. 9:1310

Stoletov, K., Strnadel, J., Zardouzian, E., Momiyama, M., Park, F.D., Kelber, J.A., Pizzo, D.P., Hoffman, R., Vandenberg, S.R., and Klemke, R.L. (2013) Role of connexins in metastatic breast cancer and melanoma brain colonization. Journal of Cell Science. 126(4):904-913

Stoletov, K., Kato, H., Zardouzian, E., Kelber, J., Yang, J., Shattil, S., and Klemke, R. (2010) Visualizing extravasation dynamics of metastatic tumor cells. Journal of Cell Science. 123(Pt 13):2332-2341

Murphy, E.A., Shields, D.J., Stoletov, K., Dneprovskaia, E., McElroy, M., Greenberg, J.I., Lindquist, J., Acevedo, L.M., Anand, S., Majeti, B.K., Tsigelny, I., Saldanha, A., Walsh, B., Hoffman, R.M., Bouvet, M., Klemke, R.L., Vogt, P.K., Arnold, L., Wrasidlo, W., and Cheresh, D.A. (2010) Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFR{beta}/B-RAF. Proceedings of the National Academy of Sciences of the United States of America. 107(9):4299-4304

Stoletov, K., Fang, L., Choi, S.H., Hartvigsen, K., Hansen, L.F., Hall, C., Pattison, J., Juliano, J., Miller, E.R., Almazan, F., Crosier, P., Witztum, J.L., Klemke, R.L., and Miller, Y.I. (2009) Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish. Circulation research. 104(8):952-960

Stoletov, K., and Klemke, R. (2008) Catch of the day: zebrafish as a human cancer model. Oncogene. 27(33):4509-4520

Wrasidlo, W., Mielgo, A., Torres, V.A., Barbero, S., Stoletov, K., Suyama, T.L., Klemke, R.L., Gerwick, W.H., Carson, D.A., and Stupack, D.G. (2008) The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8. Proceedings of the National Academy of Sciences of the United States of America. 105(7):2313-2318

Stoletov, K., Montel, V., Lester, R.D., Gonias, S.L., and Klemke, R. (2007) High-resolution imaging of the dynamic tumor cell vascular interface in transparent zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 104(44):17406-17411

NON-ZEBRAFISH PUBLICATIONS